Table of contents


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Opinion

A timely boost to research on carbon sequestration p309

Removing carbon dioxide from the atmosphere is as important as controlling emissions. Basic and applied research need to be pursued in the face of political obstacles.

doi:10.1038/43718


Reclusion to be discouraged p309

A survey has revealed that many Japanese researchers are disconnected from the outside world. Their institutions can help.

doi:10.1038/43720


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News

Gene estimate rises as US and UK discuss freedom of access p311

David Dickson

doi:10.1038/43722


Putting a price on research reading p311

Declan Butler

doi:10.1038/43725


Bombing of embassy bolsters support for science in China... p312

Tian Xuewen

doi:10.1038/43727


... as government sets sights on an 'innovation economy' p312

Tian Xuewen

doi:10.1038/43729


Japan boosts proteomics and cell biology... p313

Asako Saegusa

doi:10.1038/43732


... while France gives more power to the centre p313

Heather McCabe

doi:10.1038/43735


US Senate restores proposed cut in science budgets p314

Colin Macilwain

doi:10.1038/43738


Survey finds deep insularity among Japanese scientists p314

Asako Saegusa

doi:10.1038/43740


Celebratory pictures from Subaru p314

Asako Saegusa

doi:10.1038/43742


US warms to carbon sequestration research p315

Rex Dalton

doi:10.1038/43745


German museums face cuts p315

Quirin Schiermeier

doi:10.1038/43748


US university finds use for Air Force research reactor p316

Rex Dalton

doi:10.1038/43751


UK universities look to enterprise p316

Natasha Loder

doi:10.1038/43754


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News Analysis

Portugal's science plots its future p317

Research in Portugal has grown apace over the past decade, and the government is reviewing its achievements, problems and prospects.

Xavier Bosch

doi:10.1038/43756


News in brief p318

doi:10.1038/43759


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Correspondence

Taxonomists are an endangered species in Europe p321

Bart Buyck

doi:10.1038/43762


Don't leave the biology out of bioinformatics p321

Peter Campbell

doi:10.1038/43764


Courage could win back confidence in science p321

Susan Daenke

doi:10.1038/43766


Sprucing up one's impact factor p321

J. Gowrishankar and P. Divakar

doi:10.1038/43768


No dirty tricks in merger ballot p322

Elaine Gansz Bobo

doi:10.1038/43770


Call a halt to strong-arm tactics over GM crops p322

Manfred Philipp

doi:10.1038/43772


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Commentary

Balancing the Earth's accounts p323

Governments could safeguard the world's biodiversity with a small fraction of the money they spend on environmentally harmful subsidies.

doi:10.1038/43774


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Book Reviews

Up the river without a paddle? p325

The theory that polio-vaccine researchers are responsible for AIDS is leaky.

John P. Moore reviews The River: A Journey Back to the Source of HIV and AIDS by Edward Hooper

doi:10.1038/43778


And some big steps for science p326

Jack O. Burns reviews Exploring the Moon: The Apollo Expeditions by David M. Harland

doi:10.1038/43781


Taking the horror out of shocks p327

Hugh Freeman reviews Electroshock: Restoring the Mind by Max Fink

doi:10.1038/43784


Border control at the frontiers of science p328

N. David Mermin reviews Cultural Boundaries of Science: Credibility on the Line by Thomas F. Gieryn

doi:10.1038/43787


New in paperback p328

doi:10.1038/43789


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Millennium Essay

From horsehair to lightning rods p329

Analogy is a powerful tool in Benjamin Franklin's natural philosophy.

J.L. Heilbron

doi:10.1038/43791


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News and Views

The devil is in the distance p331

An apparent discrepancy between two different distance measurements to a faraway galaxy may lead to a revised value for the age of the Universe.

Bohdan Paczynski

doi:10.1038/43794


Biophysics: Fungus punches its way in p332

Nicholas P. Money

doi:10.1038/43797


100 and 50 years ago p332

doi:10.1038/43799


High-temperature superconductivity: Electrons pair themselves p333

Joe Orenstein

doi:10.1038/43801


Genetics: Engineering a broken heart p335

Peter J. Scambler

doi:10.1038/43804


Climatology: Extremes in the Indian Ocean p337

David Anderson

doi:10.1038/43807


Signal transduction: Mating, channels and kidney cysts p339

Scott W. Emmons and Stefan Somlo

doi:10.1038/43810


Daedalus: Fertile competition p340

David Jones

doi:10.1038/43813


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Brief Communications

Discovery of tetraploidy in a mammal p341

The red viscacha rat is unaffected by having double the usual number of chromosomes.

Milton H. Gallardo, J. W. Bickham, R. L. Honeycutt, R. A. Ojeda and N. Köhler

doi:10.1038/43815


Psychophysics: Putting plaids in perspective p342

Barton L. Anderson

doi:10.1038/43819


reply: Psychophysics: Putting plaids in perspective p342

Bart Farell

doi:10.1038/43822


Nutrition: Effect of vegetables on bone metabolism p343

Roman C. Mühlbauer and Feng Li

doi:10.1038/43824


Genetic recombination: Intron size and natural selection p344

Antonio Bernardo Carvalho and Andrew G. Clark

doi:10.1038/43827


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Article

Casein kinase I transduces Wnt signals p345

John M. Peters, Renée M. McKay, James P. McKay and Jonathan M. Graff

doi:10.1038/43830


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Letters to Nature

A distance to the galaxy NGC4258 from observations of Cepheid variable stars p351

Eyal Maoz, Jeffrey A. Newman, Laura Ferrarese, Peter B. Stetson, Stephen E. Zepf, Marc Davis, Wendy L. Freedman and Barry F. Madore

doi:10.1038/43838

See also: News and Views by Paczynski


Coupling strength of charge carriers to spin fluctuations in high-temperature superconductors p354

J. P. Carbotte, E. Schachinger and D. N. Basov

doi:10.1038/43843

See also: Letter by Carbotte et al.


Coupled ocean–atmosphere dynamics in the Indian Ocean during 1997–98 p356

Peter J. Webster, Andrew M. Moore, Johannes P. Loschnigg and Robert R. Leben

doi:10.1038/43848

See also: News and Views by Anderson


A dipole mode in the tropical Indian Ocean p360

N. H. Saji, B. N. Goswami, P. N. Vinayachandran and T. Yamagata

See also: News and Views by Anderson


Tribosphenic mammal from the North American Early Cretaceous p363

Richard L. Cifelli


Oldest playable musical instruments found at Jiahu early Neolithic site in China p366

Juzhong Zhang, Garman Harbottle, Changsui Wang and Zhaochen Kong


Incorporating rules for responding into evolutionary games p368

John M. McNamara, Catherine E. Gasson and Alasdair I Houston


The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans p371

Mei Zhen and Yishi Jin


Familial dementia caused by polymerization of mutant neuroserpin p376

Richard L. Davis, Antony E. Shrimpton, Peter D. Holohan, Charles Bradshaw, David Feiglin, George H. Collins, Peter Sonderegger, Jochen Kinter, Lyn Marie Becker, Felicitas Lacbawan, Donna Krasnewich, Maximilian Muenke, Daniel A. Lawrence, Mark S. Yerby, Cheng-Mei Shaw, Bibek Gooptu, Peter R. Elliott, John T. Finch, Robin W. Carrell and David A. Lomas


Congenital heart disease in mice deficient for the DiGeorge syndrome region p379

Elizabeth A. Lindsay, Annalisa Botta, Vesna Jurecic, Sandra Carattini-Rivera, Yin-Chai Cheah, Howard M. Rosenblatt, Allan Bradley and Antonio Baldini

See also: News and Views by Scambler


Polycystin-L is a calcium-regulated cation channel permeable to calcium ions p383

Xing-Zhen Chen, Peter M. Vassilev, Nuria Basora, Ji-Bin Peng, Hideki Nomura, Yoav Segal, Edward M. Brown, Stephen T. Reeders, Matthias A. Hediger and Jing Zhou

See also: News and Views by Emmons & Somlo


A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans p386

Maureen M. Barr and Paul W. Sternberg


Dystrophin expression in the mdx mouse restored by stem cell transplantation p390

Emanuela Gussoni, Yuko Soneoka, Corinne D. Strickland, Elizabeth A. Buzney, Mohamed K. Khan, Alan F. Flint, Louis M. Kunkel and Richard C. Mulligan


Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle p394

Steven B. Haase and Steven I. Reed


Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination p397

Roger D. Johnson, Nan Liu and Maria Jasin


Interpreting the folding kinetics of helical proteins p400

Yaoqi Zhou and Martin Karplus


Binding of double-strand breaks in DNA by human Rad52 protein p403

Eric Van Dyck, Alicja Z. Stasiak, Andrzej Stasiak and Stephen C. West


errata Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist p403

Maria Pilla, Sylvie Perachon, François Sautel, Fabrice Garrido, André Mann, Camille G. Wermuth, Jean-Charles Schwartz, Barry J. Everitt and Pierre Sokoloff


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New on the Market

E-commerce is a gas p405

Meet Noggin, and get some wheels for your glassware.


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Careers and Recruitment

How head-hunters track down the winners for science's top jobs p407

The star performers are not just head-hunted, they can write their own job descriptions. But how can a scientist reach this enviable position?

Alison Goddard


Keeping in touch with research p410

Brendan Horton


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