Access

News and Views

Nature 401, 339-340 (23 September 1999) | doi:10.1038/43810

Signal transduction: Mating, channels and kidney cysts

Scott W. Emmons1 & Stefan Somlo2

Advances in human genetics have meant that the genes mutated in human diseases can be identified exclusively by their location in the genome. But how do we work out the cellular functions of the associated protein products?

  1. Scott W. Emmons is in the Department of Molecular Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.
    e-mail: Email: emmons@aecom.yu.edu
  2. Stefan Somlo is in the Section of Nephrology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520-8029, USA.
    e-mail: Email: stefan.somlo@yale.edu