Figures and Tables

From the following article:

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Haitao Zhu, Peter Kavsak, Shirin Abdollah, Jeffrey L. Wrana and Gerald H. Thomsen

Nature 400, 687-693(12 August 1999)

doi:10.1038/23293

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Smurf1 encodes an E3 ubiquitin ligase expressed in early Xenopus development.

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Figure 2

Smurf1 expression decreases the steady-state level of Smad1 and Smad5.

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Figure 3

hSmurf1 induces Smad1 turnover and ubiquitination.

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Figure 4

Interaction of Smurf1 and Smads.

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Figure 5

Smurf1 dorsalizes ventral mesoderm and neuralizes ectoderm of Xenopus embryos.

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Figure 6

Smurf1 alters embryonic cell competence to respond to Smad1 and Smad2.

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