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Nature 399, 413-416 (3 June 1999) | doi:10.1038/20810

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Retroviruses:  Closing the joint

John M. Coffin & Naomi Rosenberg

We are starting to understand much about how retroviruses integrate their DNA into host genomes. We know, for example, how the viral integrase carries out initial events in the process.

  1. John M. Coffin and Naomi Rosenberg are in the Departments of Molecular Biology, and Microbiology and Pathology, respectively, Tufts University, 136 Harrison Avenue, Boston, Massachusetts 02111, USA.
    e-mails: Email: jcoffin-par@opal.tufts.edu
    Email: nrosenbe@opal.tufts.edu