Opinion

A suitable case for treatment p183

The decision to reprimand a leading US medical school for failing adequately to monitor the protection of human research subjects is a salutary action. It also underlines the need to ensure that monitoring is properly funded.

doi:10.1038/20247

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Celebrations for some p183

A welcome boost to the refurbishment of Britain's research infrastructure must be supported by other measures.

doi:10.1038/20249

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News

French geneticists raise worries over use of new genome funds p185

Declan Butler

doi:10.1038/20251

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Big boost demanded for France's life sciences p185

Declan Butler

doi:10.1038/20254

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Increase in German science budget a boon for women and youth p186

Alison Abbott

doi:10.1038/20256

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Europe keeps space science budget level p187

Alison Abbott

doi:10.1038/20259

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Britain finds money to renew infrastructure p187

Natasha Loder

doi:10.1038/20262

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UK debates public's role in science advice p188

David Dickson

doi:10.1038/20264

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Royal Society: GM food hazard claim is 'flawed' p188

Natasha Loder

doi:10.1038/20267

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University museum seeks independence p189

Rex Dalton

doi:10.1038/20269

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More US labs may curb visits by foreigners p189

Colin Macilwain

doi:10.1038/20272

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NIH ethics office clamps down on Duke ... p190

Meredith Wadman

doi:10.1038/20274

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... as basic scientists feel the pinch in LA p190

Meredith Wadman

doi:10.1038/20277

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Chinese reform pushes R&D into market p191

Tian Xuewen

doi:10.1038/20279

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Japan's fast-breeder loses money fast too p191

Asako Saegusa

doi:10.1038/20282

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News in Brief p192

doi:10.1038/20284

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News

India plans to demand compensation for effect of brain drain p194

doi:10.1038/20286

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Access to scientific knowledge 'should be a basic human right' p194

doi:10.1038/20288

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University women seek a central role at Budapest p194

doi:10.1038/20290

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Correspondence

Stand up for the rights of professors too p195

F. W. Taylor

doi:10.1038/20292

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Grim reality of war... and plans for the peace p195

Ian Blake

doi:10.1038/20294

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Cancer fellowships awarded on merit p195

John Cairns

doi:10.1038/20296

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Commentary

What price ergonomics? p197

Ergonomists have a say in the design of almost everything in the modern world, but there is little evidence that their methods actually work. Here is an evaluation of those methods and of the worth of ergonomics in design.

doi:10.1038/20298

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News and Views

A shared but complex bridge p199

Robert E. Kingston

doi:10.1038/20302

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Particle physics: Only a matter of time p200

Ken Peach

doi:10.1038/20306

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Cancer:  Many vessels, faulty gene p203

William G. Kaelin, Jr

doi:10.1038/20309

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100 and 50 years ago p204

doi:10.1038/20312

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Apoptosis:  Dead end for neurodegeneration? p204

Christian Haass

doi:10.1038/20314

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Statistical physics: Glasses go critical p207

Philip Ball

doi:10.1038/20317

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Earth science: Excursions in geomagnetism p207

C. G. Langereis

doi:10.1038/20320

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Cell biology: Snail mail to the nucleus p208

Iain W. Mattaj and Elena Conti

doi:10.1038/20322

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Nanotube composites: A recipe for strength p210

Paul Calvert

doi:10.1038/20326

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Neurobiology: Rain Man's revelations p211

Niels Birbaumer

doi:10.1038/20329

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Daedalus: Shear chemistry p212

David Jones

doi:10.1038/20333

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Scientific Correspondence

Birds extend their ranges northwards p213

Chris D. Thomas and Jack J. Lennon

doi:10.1038/20335

First paragraph | Full Text | PDF (133K)

Transgenic pollen harms monarch larvae p214

John E. Losey, Linda S. Rayor and Maureen E. Carter

doi:10.1038/20338

First paragraph | Full Text | PDF (161K)

The mystery of female beauty p214

J. T. Manning, R. L. Trivers, D. Singh and R. Thornhill

doi:10.1038/20341

First paragraph | Full Text | PDF (161K)

The mystery of female beauty p215

M. J. Tovée and P. L. Cornelissen

doi:10.1038/20345

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reply: The mystery of female beauty p216

Douglas W. Yu and Glenn H. Shepard

doi:10.1038/20348

First paragraph | Full Text | PDF (359K)

Book Reviews

Looping the evolutionary loop p217

Gabby Dover reviews The Origins of Life: From the Birth of Life to the Origin of Language by John Maynard Smith and Eörs Szathmary

doi:10.1038/20350

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Home is what comes naturally p217

doi:10.1038/20352

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An expletive in academia p218

Malcolm Coe reviews Merde: Excursions in Scientific, Cultural and Socio-Historical Coprology by Ralph A. Lewin

doi:10.1038/20355

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Dip into the century's technological past p219

Henry Petroski reviews Visions of Technology by Richard Rhodes

doi:10.1038/20358

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A real whodunnit p219

doi:10.1038/20360

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A bragger's guide to fuzzy objects p220

Stephen P. Maran reviews Deep Sky Companions: The Messier Objects by Stephen James O'Meara

doi:10.1038/20363

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Tale of two disciplines p220

Bernadette Bensaude-Vincent reviews Before Big Science: The Pursuit of Modern Chemistry and Physics, 1800-1940 by Mary Jo Nye

doi:10.1038/20365

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Articles

Structure of importin- bound to the IBB domain of importin- p221

Gino Cingolani, Carlo Petosa, Karsten Weis and Christoph W. Müller

doi:10.1038/20367

Abstract | Full Text | PDF (879K)

See also: News and Views by Mattaj & Conti

Structure of the nuclear transport complex karyopherin-2–RanGppNHp p230

Yuh Min Chook and Günter Blobel

doi:10.1038/20375

Abstract | Full Text | PDF (1,249K)

See also: News and Views by Mattaj & Conti

Letters to Nature

Observation of quasiparticles with one-fifth of an electron's charge p238

M. Reznikov, R. de Picciotto, T. G. Griffiths, M. Heiblum and V. Umansky

doi:10.1038/20384

First paragraph | Full Text | PDF (551K)

Two types of avalanche behaviour in granular media p241

Adrian Daerr and Stéphane Douady

doi:10.1038/20392

First paragraph | Full Text | PDF (510K)

Desorption–ionization mass spectrometry on porous silicon p243

Jing Wei, Jillian M. Buriak and Gary Siuzdak

doi:10.1038/20400

First paragraph | Full Text | PDF (302K)

Growing range of correlated motion in a polymer melt on cooling towards the glass transition p246

Christoph Bennemann, Claudio Donati, Jörg Baschnagel and Sharon C. Glotzer

doi:10.1038/20406

First paragraph | Full Text | PDF (318K)

Global changes in intensity of the Earth's magnetic field during the past 800 kyr p249

Yohan Guyodo and Jean-Pierre Valet

doi:10.1038/20420

First paragraph | Full Text | PDF (312K) | Supplementary information

See also: News and Views by Ball

Nature of the Earth's earliest crust from hafnium isotopes in single detrital zircons p252

Yuri Amelin, Der-Chuen Lee, Alex N. Halliday and Robert T. Pidgeon

doi:10.1038/20426

First paragraph | Full Text | PDF (223K) | Supplementary information

A complete human pelvis from the Middle Pleistocene of Spain p255

Juan-Luis Arsuaga, Carlos Lorenzo, José-Miguel Carretero, Ana Gracia, Ignacio Martínez, Nuria García, José-María Bermúdez de Castro and Eudald Carbonell

doi:10.1038/20430

First paragraph | Full Text | PDF (308K)

Relative risk of extinction of passerine birds on continents and islands p258

Lisa L. Manne, Thomas M. Brooks and Stuart L. Pimm

doi:10.1038/20436

First paragraph | Full Text | PDF (293K) | Supplementary information

Non-commutativity in the brain p261

Douglas B. Tweed, Thomas P. Haslwanter, Vera Happe and Michael Fetter

doi:10.1038/20441

First paragraph | Full Text | PDF (254K)

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease p263

Victor O. Ona, Mingwei Li, Jean Paul G. Vonsattel, L. John Andrews, Sohail Q. Khan, Woosik M. Chung, Ariel S. Frey, Anil S. Menon, Xiao-Jiang Li, Philip E. Stieg, Junying Yuan, John B. Penney, Anne B. Young, Jang-Ho J. Cha and Robert M. Friedlander

doi:10.1038/20446

First paragraph | Full Text | PDF (378K)

See also: News and Views by Haass

In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins p267

Qiling Xu, Georg Mellitzer, Vicky Robinson and David G. Wilkinson

doi:10.1038/20452

First paragraph | Full Text | PDF (365K)

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis p271

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang, Steven C. Clifford, Emma C. Vaux, Matthew E. Cockman, Charles C. Wykoff, Christopher W. Pugh, Eamonn R. Maher and Peter J. Ratcliffe

doi:10.1038/20459

First paragraph | Full Text | PDF (397K) | Supplementary information

See also: News and Views by Kaelin

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein p276

Thomas G. Boyer, Michelle E. D. Martin, Emma Lees, Robert P. Ricciardi and Arnold J. Berk

doi:10.1038/20466

First paragraph | Full Text | PDF (773K)

See also: News and Views by Kingston

Correction: Elasticity and rheology of iron above 220 GPa and the nature of the Earth's inner core p280

Ho-kwang Mao, Jinfu Shu, Guoyin Shen, Russell J. Hemley, Baosheng Li and Anil K. Singh

doi:10.1038/20472

Full Text | PDF (385K)

New on the Market

The ABC of DNA p281

Amplification, blood DNA, cloning kits, detectors and other aids to handling or preparing DNA make up this week's selection of recently introduced products.
Compiled in the Nature office from information provided by the manufacturers.

doi:10.1038/20476

Full Text | PDF (415K)