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Nature 398, 660-661 (22 April 1999) | doi:10.1038/19412
Open Innovation Challenges
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Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
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Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
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Dermapathologist
- Indiana University School of Medicine
- Indiana, USA
Head-Preclinical
- Syngene International
- Bangalore, Karnataka 560099 India
Biochemical sensors: Adapting to nanoscale events
Daniel Branton1 & Jene Golovchenko1
A hallmark of twentieth-century science has been the continual development of experimental strategies to observe individual atomic-scale 'events'. These strategies ultimately rely on significantly amplifying the consequences of a selective microscopic interaction, for example the chemical development of a silver halide grain in a photographic emulsion, the condensation of a droplet around a single ion in a cloud chamber, or the charge amplification in electron multiplier devices.
- Daniel Branton and Jene Golovchenko are in the Department of Molecular and Cellular Biology and the Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA.
e-mail: Email: dbranton@harvard.edu
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