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Nature 398, 462-463 (8 April 1999) | doi:10.1038/18970
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Full-Professor of Heart and Thoracic Surgery (W3) (f / m)
- Friedrich-Schiller-University Jena
- Jena Germany
Senior Scientist, Cellular & Molecular Pharmacology
- Cortex Search Inc.
- Vancouver, British Columbia
Neurobiology: Slit, the midline repellent
In bilaterally symmetric animals, communication between the left and right halves of the body is mediated by neurons that send axons across the midline of the central nervous system (CNS). These axons move along seams, or 'commissures', that are thought to be evolutionarily ancient1 — even very simple animals contract muscles on one side of their body to avoid a stimulus on the other side.
- W. A. Harris and C. E. Holt are in the Department of
Anatomy, University of Cambridge, Cambridge CB2 3DY
, UK.
e-mails: Email: harris@mole.bio.cam.ac.uk
Email: ceh@mole.bio.cam.ac.uk
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