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Volume 397 Issue 6719, 11 February 1999

Opinion

  • The sharing of data by researchers ought to be encouraged. But a compulsion to release raw data and notes in current US openness laws is the wrong way to achieve it, as is a proposed amendment.

    Opinion

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News

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News in Brief

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Correspondence

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Commentary

  • Why did a light-hearted experiment attract so much attention from the media? The episode is an interesting lesson for those wanting to explain science to the wider public -- equations do not always scare people away.

    • Len Fisher
    Commentary
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News & Views

  • Many transplant patients are given the drug cyclosporine to suppress their immune systems and prevent rejection. But cyclosporine also increases the risk of cancer, always thought to be a side effect of the depressed immune system. A new study shows that cyclosporine directly affects tumour growth and may be the culprit.

    • Gary J. Nabel
    News & Views
  • What flavour are the short-lived virtual quarks inside the nucleon? Two experiments have reported an excess of down- over up-antiquarks in the proton, contradicting expectations that the two flavours should be present in equal numbers.

    • David J. Miller
    News & Views
  • Primates — humans, monkeys and apes — have a very different retinal structure to that of other mammals. We use a trichromatic system, made up of three types of cone cell with peak sensitivities in different regions of the visual spectrum. Now, using an imaginative new technique, we can take our first look at the arrangement of these cones in the living human retina.

    • Heinz Wässle
    News & Views
  • An experimental study shows that the silica shells of diatoms, a hugely important component of the oceans' phytoplankton, can be enzymatically attacked and dissolved by bacteria. The finding extends knowledge of marine cycling of nutrients, that of silicic acid in particular, and helps explain certain patterns of shell deposition in sediments.

    • Victor Smetacek
    News & Views
  • Quasars - the most luminous type of active galactic nuclei in the Universe - may not be active all the time. There is a growing consensus that quasars may have unstable galactic disks and therefore radiate only 10% of the time. If all observed quasars represent the outburst state, then this would explain how they can be so luminous without running out of fuel.

    • Aneta Siemiginowska
    • Martin Elvis
    News & Views
  • Most cells need to be attached, through integrins, to a semi-solid meshwork called the extracellular matrix in order to survive. But if peptides with the sequence arginine-glycine-aspartic acid are added, the cells detach and die. The reason was always thought to be a blockade of integrin signalling, but a new mechanism has emerged. It seems that the RGD peptide activates caspases directly inside the cell.

    • Erkki Ruoslahti
    • John Reed
    News & Views
  • The question of whether DNA is like a wire or an insulator is a controversial one, with some experiments finding DNA is conducting and some not. A new experiment suggests that it may all depend on the DNA sequence — electron transfer in DNA only occurs with high efficiency between guanine bases. This mechanism may help explain previous disparate results.

    • Mark Ratner
    News & Views
  • Plants contain many useful substances — sugar, nicotine and steroids, for example — that are often tricky to extract, so Daedalus is developing supercritical cell culture. Because supercritical fluids are wonderful solvents, product molecules will diffuse out through the plant cell walls at an incredible rate. The technique could have applications in herbal medicine and even in genetic engineering.

    • David Jones
    News & Views
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Scientific Correspondence

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Book Review

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Review Article

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Letter

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New on the Market

  • Made-to-order proteins, a system to seek out RNA-protein interactions, new kit for enzyme kinetics and PCR-grade proteinase-K are among this selection of recent products. Compiled in the C i t Nature office from information provided by the manufacturers.

    New on the Market
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Careers and Recruitment

  • Canada needs scientists from almost all disciplines to fuel its economy. In the past, the country's attractiveness to job-seekers has been overshadowed by that of the United States, but things are changing.

    • Potter Wickware
    Careers and Recruitment
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