Opinion

Towards the acceptance of embryo stem-cell therapies p279

A quick legislative fix to the question of the use of federal funds for research with human embryo stem cells has been rightly resisted. But clear thinking and communication are needed if the research is to achieve its potential.

doi:10.1038/16738

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Pig in the middle p279

A moratorium on clinical trials of animal transplants is justified.

doi:10.1038/16740

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News

Europe is urged to hold back on xenotransplant clinical trials p281

Declan Butler

doi:10.1038/16742

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Sequence 'terrorist genes', says Venter p281

Ehsan Masood

doi:10.1038/16745

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UK women lead the way on interdisciplinary research p282

Alison Mitchell

doi:10.1038/16747

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Cancer body 'must do more for minorities' p283

Meredith Wadman

doi:10.1038/16751

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German/Swedish venture creates plant biotechnology giant p283

Quirin Schiermeier

doi:10.1038/16754

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US life scientists seek 15 per cent rise to NIH research funds p284

Meredith Wadman

doi:10.1038/16756

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Japan to try to understand quakes, not predict them p284

Asako Saegusa

doi:10.1038/16758

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China clamps down on inaccurate warnings p284

Asako Saegusa

doi:10.1038/16760

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US unveils $366 million computing boost p285

Natasha Loder

doi:10.1038/16762

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Warning on pitfalls in measuring research p285

Natasha Loder

doi:10.1038/16766

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UK gets the green light on modified crops p286

Ehsan Masood

doi:10.1038/16768

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Hopes for reform rise as Spain replaces its hard-line minister p286

Xavier Bosch

doi:10.1038/16770

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'Inadequate science' in US habitat plans p287

Tony Reichhardt

doi:10.1038/16773

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Australia battles to mine heritage site p287

Peter Pockley

doi:10.1038/16776

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News in Brief p288

doi:10.1038/16778

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Correspondence

Keele book sell-off squanders heritage p290

David Singmaster

doi:10.1038/16780

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Green campaigners undermine the IWC p290

Dan Goodman

doi:10.1038/16782

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Don't put research in a goal-based straitjacket p290

Mike Berridge

doi:10.1038/16784

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Commentary

Who will mentor the mentors? p291

In the wake of the tragic suicide of a US graduate student, research universities need to adopt a different system of monitoring the quality of graduate students' supervision. Anonymous evaluation could be the answer.

doi:10.1038/16786

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News and Views

The odds of losing at genetic roulette p293

James F. Crow

doi:10.1038/16789

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Solid-state lasers:  Lasing from a molecular sieve p294

Stephen R. Forrest

doi:10.1038/16793

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Developmental biology:  A new spin on handed asymmetry p295

Kyle J. Vogan and Clifford J. Tabin

doi:10.1038/16796

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100 and 50 years ago p295

doi:10.1038/16800

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Astrophysics:  Stress drives gas into a black hole p298

Kartik Sheth and Peter J. Teuben

doi:10.1038/16802

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Atmospheric chemistry:  Bromine explosion p299

Paul Wennberg

doi:10.1038/16805

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Oceanography:  Colour renewal from space p301

Raymond Sambrotto

doi:10.1038/16808

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Bose-Einstein condensates:  Visions of vortices p301

Sarah Tomlin

doi:10.1038/16811

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Erratum:  Origins of life: Buried beginnings p302

doi:10.1038/16814

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Daedalus:  Ultra-light glazing p302

David Jones

doi:10.1038/16816

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News and Views Feature

Getting its from bits p303

The inventor of the term 'black hole', John Wheeler, has a gift for memorable phrases. 'Getting its from bits' is another of his creations. It refers not to an object, but to a vision of a world derived from pure logic and mathematics. That vision has to a remarkable extent been embodied in modern physics — here is a progress report.

Frank Wilczek

doi:10.1038/16818

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Scientific Correspondence

Genetic tracking of a protected whale p307

Frank Cipriano and Stephen R. Palumbi

doi:10.1038/16823

First paragraph | Full Text | PDF (108K)

Motion of vortices in superconductors p308

A. Tonomura, H. Kasai, O. Kamimura, T. Matsuda, K. Harada, J. Shimoyama, K. Kishio and K. Kitazawa

doi:10.1038/16826

First paragraph | Full Text | PDF (135K) | Supplementary information

Role of the giant panda's 'pseudo-thumb' p309

Hideki Endo, Daishiro Yamagiwa, Yoshihiro Hayashi, Hiroshi Koie, Yoshiki Yamaya and Junpei Kimura

doi:10.1038/16830

First paragraph | Full Text | PDF (112K)

Yeast cell-type regulation of DNA repair p310

Stefan U. Åström, Sara M. Okamura and Jasper Rine

doi:10.1038/16833

First paragraph | Full Text | PDF (73K)

Book Reviews

The child of unfulfilled expectations p311

Malcolm R. Dando reviews America's Achilles' Heel: Nuclear, Biological, and Chemical Terrorism and Covert Attack by Richard A. Falkenrath, Robert D. Newman and Bradley A. Thayer and Superterrorism: Assassins, Mobsters, and Weapons of Mass Destruction by Glenn E. Schweitzer and Carole C. Dorsch

doi:10.1038/16836

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Of rats and psychology students p312

Adam Kuper reviews The Importance of Psychological Traits: A Cross-Cultural Study by John E. Williams, Robert C. Satterwhite and José L. Saiz

doi:10.1038/16839

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From worms to prawns p313

Diethard Tautz reviews Arthropod Relationships edited by R. A. Fortey and R. H. Thomas

doi:10.1038/16842

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You looking at me? p313

doi:10.1038/16844

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Them bones p314

doi:10.1038/16847

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Remembering Big Blue and his kin p314

Rupert Goodwins reviews A History Of Modern Computing by Paul E. Ceruzzi

doi:10.1038/16850

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Article

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis p315

Young-Yun Kong, Hiroki Yoshida, Ildiko Sarosi, Hong-Lin Tan, Emma Timms, Casey Capparelli, Sean Morony, Antonio J. Oliveira-dos-Santos, Gwyneth Van, Annick Itie, Wilson Khoo, Andrew Wakeham, Colin R. Dunstan, David L. Lacey, Tak W. Mak, William J. Boyle and Josef M. Penninger

doi:10.1038/16852

Abstract | Full Text | PDF (1,023K)

Letters to Nature

Magnetic field as a tracer of sheared gas flow in barred galaxies p324

R. Beck, M. Ehle, V. Shoutenkov, A. Shukurov and D. Sokoloff

doi:10.1038/16861

First paragraph | Full Text | PDF (986K)

See also: News and Views by Sheth & Teuben

Predicted signatures of rotating Bose–Einstein condensates p327

D. A. Butts and D. S. Rokhsar

doi:10.1038/16865

First paragraph | Full Text | PDF (2,263K)

See also: News and Views by Sambrotto

Cluster-weighted modelling for time-series analysis p329

N. Gershenfeld, B. Schoner and E. Metois

doi:10.1038/16873

First paragraph | Full Text | PDF (781K)

Confirming the continuum theory of dynamic brittle fracture for fast cracks p333

Eran Sharon and Jay Fineberg

doi:10.1038/16891

First paragraph | Full Text | PDF (414K)

A controlled-release microchip p335

John T. Santini, Jr, Michael J. Cima and Robert Langer

doi:10.1038/16898

First paragraph | Full Text | PDF (207K)

Evidence for bromine monoxide in the free troposphere during the Arctic polar sunrise p338

C. T. McElroy, C. A. McLinden and J. C. McConnell

doi:10.1038/16904

First paragraph | Full Text | PDF (252K)

See also: News and Views by Wennberg

Seismic reflection image revealing offset of Andean subduction-zone earthquake locations into oceanic mantle p341

The ANCORP Working Group

doi:10.1038/16909

First paragraph | Full Text | PDF (885K)

High genomic deleterious mutation rates in hominids p344

Adam Eyre-Walker and Peter D. Keightley

doi:10.1038/16915

First paragraph | Full Text | PDF (236K)

See also: News and Views by Crow

Monocular deprivation induces homosynaptic long-term depression in visual cortex p347

Cynthia D. Rittenhouse, Harel Z. Shouval, Michael A. Paradiso and Mark F. Bear

doi:10.1038/16922

First paragraph | Full Text | PDF (325K)

In vivo regulation of axon extension and pathfinding by growth-cone calcium transients p350

Timothy M. Gomez and Nicholas C. Spitzer

doi:10.1038/16927

First paragraph | Full Text | PDF (791K)

Secondary V(D)J recombination in B-1 cells p355

Xiao-Feng Qin, Stephan Schwers, Wong Yu, Fotini Papavasiliou, Heikyung Suh, Andre Nussenzweig, Klaus Rajewsky and Michel C. Nussenzweig

doi:10.1038/16933

First paragraph | Full Text | PDF (450K)

The 5-HT_3B subunit is a major determinant of serotonin-receptor function p359

Paul A. Davies, Marco Pistis, Michael C. Hanna, John A. Peters, Jeremy J. Lambert, Tim G. Hales and Ewen F. Kirkness

doi:10.1038/16941

First paragraph | Full Text | PDF (310K)

TPL-2 kinase regulates the proteolysis of the NF-B-inhibitory protein NF-B1 p105 p363

Mônica P. Belich, Andrés Salmerón, Leland H. Johnston and Steven C. Ley

doi:10.1038/16946

First paragraph | Full Text | PDF (470K) | Supplementary information

New on the Market

Getting into automatic gear p369

Recent additions to the market for lab automation equipment include barcode-based processors and further refinements of LIMS — lab information systems.

compiled by Brendan Horton from information provided by the manufacturers.

doi:10.1038/16955

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