Table of contents
Volume 396 Number 6712 pp603-707
Opinion
Setting a bad example on AIDS p603
South Africa has a unique opportunity to play a key role in creating effective health-care systems in sub-Saharan Africa. It must not squander this opportunity by rejecting the help offered by science.
doi:10.1038/25174
Protest in Paris p603
The successful reform of French science needs a greater commitment to openness and consultation.
doi:10.1038/25176
News
More foreign research students stay in US to cash in on boom p605
Colin Macilwain
doi:10.1038/25178
UN stands up for East German scientists p605
Quirin Schiermeier
doi:10.1038/25181
Budget block on US bid to rejoin Unesco... p606
Ehsan Masood
doi:10.1038/25183
... as Australian minister hits out at agency over heritage sites p606
Peter Pockley
doi:10.1038/25185
France's scientists rally to oppose Allègre's reforms p607
Declan Butler
doi:10.1038/25188
UK set to back industrial spin-offs from research p607
Natasha Loder
doi:10.1038/25191
Claims of hidden agenda on French waste p608
Eric Glover
doi:10.1038/25193
Search hopes to detect laser signals from extraterrestrial life p608
Steve Nadis
doi:10.1038/25195
European physicists split on new magnet p609
Alison Abbott
doi:10.1038/25198
German standstill as fewer chairs available p609
Tilmann Kiessling
doi:10.1038/25201
Italy backs Third World science body ... p610
David Dickson
doi:10.1038/25203
... as African women get research career boost p610
Natasha Loder
doi:10.1038/25205
News Analysis
Israeli industry asks for boost to R&D p611
High-technology industry makes up most of Israel's industrial exports. But leading companies, worried by the government's failure to invest in research and development, are threatening to take this work abroad.
Haim Watzman
doi:10.1038/25208
News in Brief p612
doi:10.1038/25211
Correction: Japanese science ministry expects large funding boost p613
doi:10.1038/25213
Correspondence
Protest at Nobel omission of Moncada p614
José Benjamín López Guillén, Eduardo A. Espinoza Fiallos, Ana Belén Castillo, Gustavo A. Vallejo, Jack R. Lancaster, Jr and Bo G. Malmström
doi:10.1038/25215
Bitter pill to swallow over medical education p614
Hartmut H. Glossmann and Bernhard A. Peskar
doi:10.1038/25217
Commentary
Benchmarking international research p615
doi:10.1038/25219
Abstract | Full Text | PDF (186K)
News and Views
C-quest in the Amazon Basin p619
I. Colin Prentice and Jon Lloyd
doi:10.1038/25224
Genome sequencing: The worm revealed p620
Martin Chalfie
doi:10.1038/25228
Biomechanics: The quirks of jerks p621
M. A. R. Koehl
doi:10.1038/25231
Structural biology: The ABC of a versatile engine p623
Michael J. Welsh, Andrew D. Robertson and Lynda S. Ostedgaard
doi:10.1038/25234
Antigen presentation: A protease draws first blood p625
Matthew Bogyo and Hidde L. Ploegh
doi:10.1038/25238
Superconductivity: An analogue of superfluid 3He p627
Maurice Rice
doi:10.1038/25241
100 and 50 years ago p627
doi:10.1038/25243
Atmospheric chemistry: Smelly cats p628
Sarah Tomlin
doi:10.1038/25245
Apoptosis: Death deceiver p629
Douglas R. Green
doi:10.1038/25248
Immunology: The thymus in the age of retirement p630
Hans-Reimer Rodewald
doi:10.1038/25251
Daedalus: Boxing the compass p631
David Jones
doi:10.1038/25255
Obituary: Nicholas Kurti (1908-98) p632
W. Graham Richards
doi:10.1038/25257
Science and Image
Stilled splashes p633
The physicist Arthur Worthington was intrigued by the beauty to be found in photographs of splashes produced when bodies of various shapes and sizes fall into fluids. The legacy of his enthusiasm is with us today.
Martin Kemp
doi:10.1038/25260
Scientific Correspondence
Do all freshwater eels migrate? p635
Katsumi Tsukamoto, Izumi Nakai and W-.V. Tesch
doi:10.1038/25264
First paragraph | Full Text | PDF (203K)
Trick or treat from food endocannabinoids? p636
Vincenzo Di Marzo, Nunzio Sepe, Luciano De Petrocellis, Alvin Berger, Gayle Crozier, Ester Fride and Raphael Mechoulam
doi:10.1038/25267
First paragraph | Full Text | PDF (258K)
Reply: Trick or treat from food endocannabinoids? p636
Massimiliano Beltramo and Daniele Piomelli
doi:10.1038/25270
First paragraph | Full Text | PDF (258K)
Honeybees link sights to smells p637
M. V. Srinivasan, S. W. Zhang and H. Zhu
doi:10.1038/25272
First paragraph | Full Text | PDF (243K)
Immobile plasticizer in flexible PVC p638
A. Jayakrishnan and S. Lakshmi
doi:10.1038/25275
First paragraph | Full Text | PDF (156K)
Book Reviews
The secret life of the Neanderthal p639
Nicolaas A. Rupke
doi:10.1038/25278
An army of zombies p639
Raymond J. Dolan
doi:10.1038/25281
Knowing your roots p640
Simon Hillson
doi:10.1038/25284
Far beneath in the abysmal sea p641
Martin Wells
doi:10.1038/25287
The cosmic rain p642
David Miller
doi:10.1038/25290
Review
Genetic instabilities in human cancers p643
Christoph Lengauer, Kenneth W. Kinzler and Bert Vogelstein
doi:10.1038/25292
Abstract | Full Text | PDF (515K) | Supplementary information
Letters to Nature
Coexisting conical bipolar and equatorial outflows from a high-mass protostar p650
L. J. Greenhill, C. R. Gwinn, C. Schwartz, J. M. Moran and P. J. Diamond
doi:10.1038/25299
First paragraph | Full Text | PDF (544K)
Experimental observation of relativistic nonlinear Thomson scattering p653
Szu-yuan Chen, Anatoly Maksimchuk and Donald Umstadter
doi:10.1038/25303
First paragraph | Full Text | PDF (249K)
Electrostatically driven charge-ordering in Fe2OBO3 p655
J. P. Attfield, A. M. T. Bell, L. M. Rodriguez-Martinez, J. M. Greneche, R. J. Cernik, J. F. Clarke and D. A. Perkins
doi:10.1038/25309
First paragraph | Full Text | PDF (290K) | Supplementary information
Spin-triplet superconductivity in Sr2RuO4 identified by 17O Knight shift p658
K. Ishida, H. Mukuda, Y. Kitaoka, K. Asayama, Z. Q. Mao, Y. Mori and Y. Maeno
doi:10.1038/25315
First paragraph | Full Text | PDF (296K) | Supplementary information
See also: News and Views by Rice
Polysaccharide elasticity governed by chair–boat transitions of the glucopyranose ring p661
Piotr E. Marszalek, Andres F. Oberhauser, Yuan-Ping Pang and Julio M. Fernandez
doi:10.1038/25322
First paragraph | Full Text | PDF (1,357K)
Effect of interannual climate variability on carbon storage in Amazonian ecosystems p664
Hanqin Tian, Jerry M. Melillo, David W. Kicklighter, A. David McGuire, John V. K. Helfrich, III, Berrien Moore, III and Charles J. Vörösmarty
doi:10.1038/25328
First paragraph | Full Text | PDF (220K)
See also: News and Views by Prentice & Lloyd
Ratios of ferrous to ferric iron from nanometre-sized areas in minerals p667
Laurence A. J. Garvie and Peter R. Buseck
doi:10.1038/25334
First paragraph | Full Text | PDF (403K)
Mice lacking melanin-concentrating hormone are hypophagic and lean p670
Masako Shimada, Nicholas A. Tritos, Bradford B. Lowell, Jeffrey S. Flier and Eleftheria Maratos-Flier
doi:10.1038/25341
First paragraph | Full Text | PDF (385K)
GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2 p674
Kenneth A. Jones, Beth Borowsky, Joe A. Tamm, Douglas A. Craig, Margaret M. Durkin, Meng Dai, Wen-Jeng Yao, Mary Johnson, Caryn Gunwaldsen, Ling-Yan Huang, Cheng Tang, Quanrong Shen, John A. Salon, Kelley Morse, Thomas Laz, Kelli E. Smith, Dhanapalan Nagarathnam, Stewart A. Noble, Theresa A. Branchek and Christophe Gerald
doi:10.1038/25348
First paragraph | Full Text | PDF (1,455K)
Heterodimerization is required for the formation of a functional GABAB receptor p679
Julia H. White, Alan Wise, Martin J. Main, Andrew Green, Neil J. Fraser, Graham H. Disney, Ashley A. Barnes, Piers Emson, Steven M. Foord and Fiona H. Marshall
doi:10.1038/25354
First paragraph | Full Text | PDF (1,082K)
GABAB-receptor subtypes assemble into functional heteromeric complexes p683
Klemens Kaupmann, Barbara Malitschek, Valerie Schuler, Jakob Heid, Wolfgang Froestl, Pascal Beck, Johannes Mosbacher, Serge Bischoff, Akos Kulik, Ryuichi Shigemoto, Andreas Karschin and Bernhard Bettler
doi:10.1038/25360
First paragraph | Full Text | PDF (2,341K)
Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy p687
Björn C. Schroeder, Christian Kubisch, Valentin Stein and Thomas J. Jentsch
doi:10.1038/25367
First paragraph | Full Text | PDF (2,903K)
Changes in thymic function with age and during the treatment of HIV infection p690
Daniel C. Douek, Richard D. McFarland, Philip H. Keiser, Earl A. Gage, Janice M. Massey, Barton F. Haynes, Michael A. Polis, Ashley T. Haase, Mark B. Feinberg, John L. Sullivan#, Beth D. Jamieson, Jerome A. Zack, Louis J. Picker and Richard A. Koup
doi:10.1038/25374
First paragraph | Full Text | PDF (551K)
See also: News and Views by Rodewald
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation p695
Bénédicte Manoury, Eric W. Hewitt, Nick Morrice, Pam M. Dando, Alan J. Barrett and Colin Watts
doi:10.1038/25379
First paragraph | Full Text | PDF (380K)
See also: News and Views by Bogyo & Ploegh
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer p699
Robert M. Pitti, Scot A. Marsters, David A. Lawrence, Margaret Roy, Frank C. Kischkel, Patrick Dowd, Arthur Huang, Christopher J. Donahue, Steven W. Sherwood, Daryl T. Baldwin, Paul J. Godowski, William I. Wood, Austin L. Gurney, Kenneth J. Hillan, Robert L. Cohen, Audrey D. Goddard, David Botstein and Avi Ashkenazi
doi:10.1038/25387
First paragraph | Full Text | PDF (1,800K)
See also: News and Views by Green
Crystal structure of the ATP-binding subunit of an ABC transporter p703
Li-Wei Hung, Iris Xiaoyan Wang, Kishiko Nikaido, Pei-Qi Liu, Giovanna Ferro-Luzzi Ames and Sung-Hou Kim
doi:10.1038/25393
First paragraph | Full Text | PDF (1,811K)
See also: News and Views by Welsh et al.
Erratum: Visible viruses p707
Martin Kemp
doi:10.1038/25401
Correction: Crystal structure of a bacterial
signal peptidase in complex with a 
-lactam inhibitor p707
Mark Paetzel, Ross E. Dalbey and Natalie C. J. Strynadka
doi:10.1038/25403
