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Nature 396, 625-627 (17 December 1998) | doi:10.1038/25238
Antigen presentation: A protease draws first blood
Matthew Bogyo1 & Hidde L. Ploegh1
Biologists used to approach proteolysis with ambivalence and apprehension. Proteolytic cleavages cannot be predicted from a cloned sequence and, because it can destroy or confound one's favourite subjects, proteolysis is ignored at one's peril.
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