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Nature 396, 623-624 (17 December 1998) | doi:10.1038/25234

Open Innovation Challenges

  • Single-cell Analysis Platform

    • Deadline: Dec 02 2009
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    This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...

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    The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....

Structural biology:  The ABC of a versatile engine

Michael J. Welsh1, Andrew D. Robertson1 & Lynda S. Ostedgaard1

Early in evolution an engine called a nucleotide-binding domain (NBD) was created. As evolution progressed, this engine proved quite adaptable — it now powers an amazing variety of machines.

  1. Michael J. Welsh, Andrew D. Robertson and Lynda S. Ostedgaard are at the University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.
    e-mail: Email: mjwelsh@blue.weeg.uiowa.edu