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Nature 396, 111-113 (12 November 1998) | doi:10.1038/24036
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John Innes Centre Project Leader in Plant or Microbial Sciences
- University of East Anglia
- Norwich, NR4 7TJ, UK
Academic Surgical Pathologists GI / Breast / GYN
- Medical College of Wisconsin
- Milwaukee, Wisconsin, USA
Protein transport: Life and death of a signal peptide
Gunnar von Heijne1
Signal peptides target proteins for secretion in both prokaryotic and eukaryotic cells. A deceptively simple-looking amino-terminal extension on the newly synthesized polypeptide chain, the signal peptide takes part in an array of protein-protein and protein-lipid interactions.
- Gunnar von Heijne is in the Department of Biochemistry, Arrhenius Laboratories, Stockholm University, S-106 91 Stockholm, Sweden.
e-mail: Email: gunnar@biokemi.su.se
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