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Nature 395, 625 (15 October 1998) | doi:10.1038/27023

Hidden role of a gas of many parts

Rory Howlett

Interest in nitric oxide has exploded in recent years due to the recognition that the gas plays an important role in many physiological processes, and that manipulating the nitric oxide signalling pathway can have major medical benefits. But, only 30 years ago, the idea that a gas could have biological functions would have seemed far-fetched.