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Correspondence

Nature 395, 431 (1 October 1998) | doi:10.1038/26602

Hope or hype for lexipafant?

Fikri M. Abu-Zidan1

  1. Department of Surgery, Auckland Hospital, Faculty of Medicine and Health Science, University of Auckland, Park Road, Auckland, New Zealand
    e-mail: Email: f.abu-zidan@auckland.ac.nz

I read the News article on the large multicentre trial of lexipafant (Zacutex) in severe pancreatitis and the response of the chief executive of British Biotechnology (Nature 393, 291; 1998, Nature 393, 299; 1998 & Nature 393, 509; 1998). I used lexipafant to block platelet-activating factor in different models of shock and sepsis during 1993-95 at Linköping University, Sweden.