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Nature 395, 221-223 (17 September 1998) | doi:10.1038/26111

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Mutagenesis:  Purposeful mutations

Myron F. Goodman1

When DNA is passed from mother to daughter cells during replication, several mechanisms ensure that this occurs with a minimum of mutations. These include proofreading exonucleases and post-replication mismatch-repair enzymes1.

  1. Myron F. Goodman is in the Department of Biology, Program in Molecular Biology, Stauffer Hall of Science 172, University of Southern California, Los Angeles, California 90089-1340, USA.
    e-mail: Email: mgoodman@rcf.usc.edu