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Nature 394, 515 (6 August 1998) | doi:10.1038/28927

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Pesticide tests on humans cause concern

Meredith Wadman

The US Environmental Protection Agency (EPA) said last week that it was "deeply concerned" that some pesticide manufacturers appeared to be engaging in health-effects studies on human subjects "as a way to avoid more protective results from animal tests".The statement came as it emerged that a Californian pesticide company has helped to pay for a study at the University of California, Davis, of human volunteers who were exposed to methyl isothiocyanate, the active ingredient in metam sodium, a potent soil fumigant (see box).