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Nature 394, 426-427 (30 July 1998) | doi:10.1038/28752
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BE / BC Gastroenterologist
- Meadville Medical Center
- Meadville, PA
Faculty Positions
- University of Texas Medical Branch
- Galveston, TX United States
Vesicular transport: Sticky fingers grab a lipid
Claudia Wiedemann1 & Shamshad Cockcroft1
Inositol lipids first came into the limelight in the 1980s when they were identified as a source of second messengers after cleavage by phospholipase C. In the 1990s they emerged under a different guise — intact inositol lipids were found to interact directly with proteins and to participate in exocytosis (release of messenger molecules from cells), cytoskeletal reorganization and vesicle transport.
- Claudia Wiedemann and Shamshad Cockcroft are in the Department of Physiology, Rockefeller Building, University College, London WC1E 6JJ, UK.
e-mails: Email: c.wiedemann@ucl.ac.uk Email: s.cockcroft@ucl.ac.uk
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