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Nature 394, 426-427 (30 July 1998) | doi:10.1038/28752

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Vesicular transport:  Sticky fingers grab a lipid

Claudia Wiedemann1 & Shamshad Cockcroft1

Inositol lipids first came into the limelight in the 1980s when they were identified as a source of second messengers after cleavage by phospholipase C. In the 1990s they emerged under a different guise — intact inositol lipids were found to interact directly with proteins and to participate in exocytosis (release of messenger molecules from cells), cytoskeletal reorganization and vesicle transport.

  1. Claudia Wiedemann and Shamshad Cockcroft are in the Department of Physiology, Rockefeller Building, University College, London WC1E 6JJ, UK.
    e-mails: Email: c.wiedemann@ucl.ac.uk Email: s.cockcroft@ucl.ac.uk