Opinion

Potential weaknesses in unaccustomed generosity p303

The large boost of funds for British science is an essential means to arrest its decline. Attention now needs to focus on ensuring these funds are distributed fairly.

doi:10.1038/28443

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Adult cloning marches on p303

New results on cloning technology increase the urgency for regulations to ensure its responsible use.

doi:10.1038/28445

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News

Gore calls for action on climate change as Congress stalls p305

Colin Macilwain

doi:10.1038/28447

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Indian atomic chief is refused US visa p305

K. S. Jayaraman

doi:10.1038/28450

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NIH streamlines research grants process p306

Meredith Wadman

doi:10.1038/28452

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Bill tightens law against genetic discrimination by health insurers p306

Meredith Wadman

doi:10.1038/28454

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UK universities get another funding boost p307

David Dickson

doi:10.1038/28457

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New Zealand enjoys science jamboree p307

Peter Pockley

doi:10.1038/28460

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Plan for government researchers in Japan to work in industry p308

Asako Saegusa

doi:10.1038/28462

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Fraud squad files report to prosecutor in Inserm case p308

Declan Butler

doi:10.1038/28464

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France sets high targets for impact factors and patents p309

Declan Butler

doi:10.1038/28466

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Congress revives hopes for solar power satellites p309

Tony Reichhardt

doi:10.1038/28468

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Accelerator project digs itself into a hole p309

Carl Levitin

doi:10.1038/28470

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News Analysis

Hungary pushes for further reform p310

Hungarian science has undergone considerable post-communist reform, but the country's academy of sciences feels that further change is needed to allow it to take tough decisions on spending priorities.

Alison Abbott

doi:10.1038/28472

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News in Brief p311

doi:10.1038/28475

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Correspondence

Leading scientists still reject God p313

Edward J. Larson and Larry Witham

doi:10.1038/28478

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Dilemma over genetics and population in China p313

Sun-Wei Guo, Chang-Jiang Zheng and C. C. Li

doi:10.1038/28481

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Science in the firing line in Argentina p314

Marcelino Cereijido

doi:10.1038/28483

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News and Views

Dolly is a clone — and no longer alone p315

Davor Solter

doi:10.1038/28485

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Nonlinear dynamics:  Death by delay p316

Steven H. Strogatz

doi:10.1038/28488

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Ras signalling:  Caught in the act of the switch-on p317

Fred Wittinghofer

doi:10.1038/28492

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100 and 50 years ago p319

doi:10.1038/28496

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Earthquakes:  Cracking Los Angeles p320

John H. Shaw

doi:10.1038/28498

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Palaeontology:  An Asian Grande Coupure p321

Jean-Louis Hartenberger

doi:10.1038/28501

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Pulsars:  A period of change p323

Nicholas E. White

doi:10.1038/28503

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Molecular motors:  Keeping up with the F₁-ATPase p324

Howard C. Berg

doi:10.1038/28506

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Combinatorial chemistry:  Connecting with catalysis p325

Ian E. Maxwell

doi:10.1038/28510

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Palaeoanthropology:  Lucy takes a stroll p325

Tim Lincoln

doi:10.1038/28512

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Daedalus:  Wet metallic hydrogen p326

David Jones

doi:10.1038/28515

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Science and Image

Wheatstone's waves p327

The nineteenth-century creative genius Sir Charles Wheatstone invented a wave machine and other 'philosophical toys' that had a serious purpose in demonstrating the laws of physics.

Martin Kemp

doi:10.1038/28517

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Scientific Correspondence

DNA microsatellite analysis of Dolly p329

David Ashworth, Matthew Bishop, Keith Campbell, Alan Colman, Alex Kind, Angelika Schnieke, Sarah Blott, Harry Griffin, Chris Haley, Jim McWhir and Ian Wilmut

doi:10.1038/28521

First paragraph | Full Text | PDF (285K)

See also: News and Views by Solter

DNA fingerprinting Dolly p329

Esther N. Signer, Yuri E. Dubrova, Alec J. Jeffreys, Colin Wilde, Lynn M. B. Finch, Michelle Wells and Malcolm Peaker

doi:10.1038/28524

First paragraph | Full Text | PDF (285K)

See also: News and Views by Solter

A cellulase gene of termite origin p330

Hirofumi Watanabe, Hiroaki Noda, Gaku Tokuda and Nathan Lo

doi:10.1038/28527

First paragraph | Full Text | PDF (428K)

Arctic springtime depletion of mercury p331

W. H. Schroeder, K. G. Anlauf, L. A. Barrie, J. Y. Lu, A. Steffen, D. R. Schneeberger and T. Berg

doi:10.1038/28530

First paragraph | Full Text | PDF (466K)

Book Reviews

The joy of secants p333

Jeremy Gray

doi:10.1038/28533

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Carnivores in living colour p334

Adrian M. Lister

doi:10.1038/28536

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Instrumental insects p335

Darryl T. Gwynne and Glenn K. Morris

doi:10.1038/28540

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Holy prehistory p335

Nicholas J. Saunders reviews From Black Land To Fifth Sun: The Science of Sacred Sites by Brian Fagan

doi:10.1038/28542

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Is anybody out there? p336

David W. Hughes

doi:10.1038/28546

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Article

The structural basis of the activation of Ras by Sos p337

P. Ann Boriack-Sjodin, S. Mariana Margarit, Dafna Bar-Sagi and John Kuriyan

doi:10.1038/28548

Abstract | Full Text | PDF (643K)

See also: News and Views by Wittinghofer

Letters to Nature

A millisecond pulsar in an X-ray binary system p344

Rudy Wijnands and Michiel van der Klis

doi:10.1038/28557

First paragraph | Full Text | PDF (232K)

See also: News and Views by White

The two-hour orbit of a binary millisecond X-ray pulsar p346

Deepto Chakrabarty and Edward H. Morgan

doi:10.1038/28561

First paragraph | Full Text | PDF (244K)

See also: News and Views by White

Optical alignment and spinning of laser-trapped microscopic particles p348

M. E. J. Friese, T. A. Nieminen, N. R. Heckenberg and H. Rubinsztein-Dunlop

doi:10.1038/28566

First paragraph | Full Text | PDF (493K)

High-throughput screening of solid-state catalyst libraries p350

Selim M. Senkan

doi:10.1038/28575

First paragraph | Full Text | PDF (297K)

See also: News and Views by Maxwell

Unexpectedly high concentrations of molecular chlorine in coastal air p353

C. W. Spicer, E. G. Chapman, B. J. Finlayson-Pitts, R. A. Plastridge, J. M. Hubbe, J. D. Fast and C. M. Berkowitz

doi:10.1038/28584

First paragraph | Full Text | PDF (288K)

Escape tectonics in the Los Angeles metropolitan region and implications for seismic risk p356

Christian Walls, Thomas Rockwell, Karl Mueller, Yehuda Bock, Simon Williams, John Pfanner, James Dolan and Peng Fang

doi:10.1038/28590

First paragraph | Full Text | PDF (601K)

See also: News and Views by Shaw

Evidence from the asymmetry of fast-spreading ridges that the axial topographic high is due to extensional stresses p360

Michael A. Eberle and Donald W. Forsyth

doi:10.1038/28596

First paragraph | Full Text | PDF (223K)

Faunal turnovers of Palaeogene mammals from the Mongolian Plateau p364

Jin Meng and Malcolm C. McKenna

doi:10.1038/28603

First paragraph | Full Text | PDF (394K) | Supplementary information

See also: News and Views by Hartenberger

Veil architecture in a sulphide-oxidizing bacterium enhances countercurrent flux p367

Tom Fenchel and Ronnie N. Glud

doi:10.1038/28609

First paragraph | Full Text | PDF (560K)

Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei p369

T. Wakayama, A. C. F. Perry, M. Zuccotti, K. R. Johnson and R. Yanagimachi

doi:10.1038/28615

First paragraph | Full Text | PDF (600K)

See also: News and Views by Solter

Defects in somite formation in lunatic fringe-deficient mice p374

Nian Zhang and Thomas Gridley

doi:10.1038/28625

First paragraph | Full Text | PDF (486K)

lunatic fringe is an essential mediator of somite segmentation and patterning p377

Yvonne A. Evrard, Yi Lun, Alexander Aulehla, Lin Gan and Randy L. Johnson

doi:10.1038/28632

First paragraph | Full Text | PDF (768K)

A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock p381

Jian M. Ding, Gordon F. Buchanan, Shelley A. Tischkau, Dong Chen, Liana Kuriashkina, Lia E. Faiman, Joan M. Alster, Peter S. McPherson, Kevin P. Campbell and Martha U. Gillette

doi:10.1038/28639

First paragraph | Full Text | PDF (268K)

High-frequency firing helps replenish the readily releasable pool of synaptic vesicles p384

Lu-Yang Wang and Leonard K. Kaczmarek

doi:10.1038/28645

First paragraph | Full Text | PDF (301K)

An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy p388

Kazuhiro Kobayashi, Yutaka Nakahori, Masashi Miyake, Kiichiro Matsumura, Eri Kondo-Iida, Yoshiko Nomura, Masaya Segawa, Mieko Yoshioka, Kayoko Saito, Makiko Osawa, Kenzo Hamano, Youichi Sakakihara, Ikuya Nonaka, Yasuo Nakagome, Ichiro Kanazawa, Yusuke Nakamura, Katsushi Tokunaga and Tatsushi Toda

doi:10.1038/28653

First paragraph | Full Text | PDF (413K)

Developmental selection of var gene expression in Plasmodium falciparum p392

Qijun Chen, Victor Fernandez, Annika Sundström, Martha Schlichtherle, Santanu Datta, Per Hagblom and Mats Wahlgren

doi:10.1038/28660

First paragraph | Full Text | PDF (340K)

Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor p395

Thomas P. J. Garrett, Neil M. McKern, Meizhen Lou, Maurice J. Frenkel, John D. Bentley, George O. Lovrecz, Thomas C. Elleman, Leah J. Cosgrove and Colin W. Ward

doi:10.1038/28668

First paragraph | Full Text | PDF (474K)

New on the Market

Instrumental advances p401

doi:10.1038/28676

Abstract | Full Text | PDF (464K)