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Nature 394, 125-126 (9 July 1998) | doi:10.1038/28039
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Cell motility: Actin branches out
Laura M. Machesky1 & Michael Way2
The ability of cells to move is essential for the development and survival of multicellular organisms, yet it can also be detrimental — when cancer cells migrate to distant parts of the body and colonize new tumours, for example. Cell movement is thought to be driven largely by the polymerization of actin monomers into filaments near the plasma membrane, and by the contractile forces of myosin motors found deeper in the cell.
- Laura M. Machesky is at the MRC Laboratory for Molecular Cell Biology, Gower Street, London WC1E 6BT, UK.
e-mail: Email: dmcblam@ucl.ac.uk - Michael Way is at the European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.
e-mail: Email: way@embl-heidelberg.de
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