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Nature 393, 413-414 (4 June 1998) | doi:10.1038/30845

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Immunology:  Licence to kill

Antonio Lanzavecchia1

When the body's own cells become infected, the immune system can take the extreme step of killing them to preserve the rest of the organism. It is no surprise that this potentially dangerous mechanism has to be kept under strict control, and on pages 4741, 4782 and 4803 of this issue, three groups suggest a new mechanism by which this control operates.

  1. Antonio Lanzavecchia is at the Basel Institute for Immunology, Grenzacherstrasse 487, CH 4005 Basel, Switzerland.
    e-mail: Email: lanzavecchia@bii.ch