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Nature 393, 311-312 (28 May 1998) | doi:10.1038/30613
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Gene silencing: Methylation meets acetylation
Timothy H. Bestor1
Promoters can sometimes be oblivious to transcription factors. For example, the 'silent' alleles of imprinted mammalian genes clearly have all the factors needed for their transcription, as shown by the active transcription of the other allele in the same nucleus.
- Timothy H. Bestor is in the Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, 701 West 168th Street, New York, New York 10032, USA.
e-mail: Email: THB12@columbia.edu
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