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Nature 393, 311-312 (28 May 1998) | doi:10.1038/30613

Gene silencing:  Methylation meets acetylation

Timothy H. Bestor1

Promoters can sometimes be oblivious to transcription factors. For example, the 'silent' alleles of imprinted mammalian genes clearly have all the factors needed for their transcription, as shown by the active transcription of the other allele in the same nucleus.