FIGURE 3. Repeated unfolding/refolding cycles of a single recombinant TNfnALL protein.
From the following article:
The molecular elasticity of the extracellular matrix protein tenascin
Andres F. Oberhauser, Piotr E. Marszalek, Harold P. Erickson and Julio M. Fernandez
Nature 393, 181-185(14 May 1998)
doi:10.1038/30270
A, Three consecutive unfolding/refolding cycles separated by 5 s (a, b) and 15 s (b, c). a, Upwards arrow indicates extension and downwards arrow indicates relaxation. B, Dependence of the unfolding forces on pulling speed. The filled circles show the result of five different experiments (n = 191). The solid line is the result of a Monte Carlo simulation of the speed dependency of the force peaks measured during the simulated unfolding of ten FN-III domains placed in series. The inset shows z-axis motion as a function of time.
