Table of contents


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Opinion

A culture whose time is past p211

France's scientific and technological structures have no choice but to undergo a revolution. The government must encourage a climate of competitiveness and risk-taking required to ensure a strong scientific future.

doi:10.1038/32476


Competitiveness versus conferences? p211

A small rebellion reflects postdocs' dissatisfaction with meetings of questionable value.

doi:10.1038/32478


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News

German Greens soften views on biotech as power edges closer p213

Quirin Schiermeier

doi:10.1038/32480


Clinton told to speed up plutonium disposal p213

Colin Macilwain

doi:10.1038/32483


Innovation 'stifled' in France, says report p214

Declan Butler

doi:10.1038/32485


Allègre seeks boost for young researchers p214

Declan Butler

doi:10.1038/32488


Asteroid watchers debate false alarm p215

Tony Reichhardt

doi:10.1038/32490


Decline in Indian publications raises alarm p215

K. S. Jayaraman

doi:10.1038/32493


Canada's environment act under attack... p216

David Spurgeon

doi:10.1038/32495


...as federal agency is accused of undermining pollution watchdog p216

David Spurgeon

doi:10.1038/32498


UK physics 'must focus on breakthroughs' p217

Ehsan Masood

doi:10.1038/32500


Britain opens up science advisory panel p217

Colin Macilwain

doi:10.1038/32503


Dating in doubt as researcher is probed p218

Rex Dalton

doi:10.1038/32505


Japan's genome programme goes ahead, with protein analysis p219

Asako Saegusa

doi:10.1038/32510


News in Brief p220

doi:10.1038/32512


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Correspondence

Some issues for the biosafety protocol p221

Henry I. Miller, Charles J. Arntzen, Roger N. Beachy, R. James Cook, Susanne L. Huttner, Donald Kennedy, Calvin O. Qualset, Peter H. Raven and Anne K. Vidaver

doi:10.1038/32514


A pawn in a conspiracy? p221

George A. Mashour

doi:10.1038/32516


Early Alpine industry p221

A. J. (Tom) van Loon

doi:10.1038/32518


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News and Views

A checkpoint on the road to cancer p223

Terry L. Orr-Weaver and Robert A. Weinberg

doi:10.1038/32520


Geophysics:  Finding chaos in abyssal hills p224

John A. Goff

doi:10.1038/32524


100 and 50 years ago p225

doi:10.1038/32527


Malaria transmission:  Has the ignition key been found? p227

Richard Carter and Lisa Ranford-Cartwright

doi:10.1038/32529


Galaxy formation:  Clumps and bumps on the road p228

Melinda L. Weil

doi:10.1038/32532


Ecology:  Nipped in the bud p229

Tim Lincoln

doi:10.1038/32536


Visual processing:  How to know where to go p231

Roland Hengstenberg

doi:10.1038/32539


High-pressure physics:  The double identity of ice X p232

José Teixeira

doi:10.1038/32542


Neuroscience:  Right on in sign language p233

Eraldo Paulesu and Jacques Mehler

doi:10.1038/32546


Daedalus:  Free captive fish p234

David Jones

doi:10.1038/32549


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Art and Science

De Vries's varieties p235

Scientists have always had an irresistible urge to list and classify. But the work of the artist Herman de Vries reminds us that nature's variety will always defy our attempts at imposing a fixed order.

Martin Kemp

doi:10.1038/32551


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Scientific Correspondence

Carbon nano-cages created as cubes p237

Yahachi Saito and Takehisa Matsumoto

doi:10.1038/32555


Tight knot values deviate from linear relations p237

Jason Cantarella, Robert B. Kusner and John M. Sullivan

doi:10.1038/32558


Four-thirds power law for knots and links p238

Gregory Buck

doi:10.1038/32561


Heartbeat synchronized with ventilation p239

Carsten Schäfer, Michael G. Rosenblum, Jürgen Kurths and Hans-Henning Abel

doi:10.1038/32567


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Book Reviews

Teasing with winsome heresy p241

John Maddox reviews The Ascent of Science by Brian Silver

doi:10.1038/32571


Mesmerized by meteors p241

doi:10.1038/32573


Engineering branch p242

Julian Vincent reviews Design in Nature: Learning from Trees by Claus Mattheck

doi:10.1038/32576


Marrow of the skull bears fruit p242

doi:10.1038/32578


Decisive action p242

Valerie M. Chase reviews Sources of Power: How People Make Decisions by Gary Klein

doi:10.1038/32581


Benevolent nuclei p243

Robert W. Cahn reviews Tracks to Innovation by Robert L. Fleischer

doi:10.1038/32583


In retrospect:  chosen by Carl Djerassi p244

Carl Djerassi reviews The Struggles of Albert Woods by William Cooper

doi:10.1038/32585


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Article

Dendritic cells and the control of immunity p245

Jacques Banchereau and Ralph M. Steinman

doi:10.1038/32588


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Letters to Nature

Clumpy star-forming regions as the origin of the peculiar morphology of high-redshift galaxies p253

Masafumi Noguchi

doi:10.1038/32596

See also: News and Views by Weil


Evidence against turbulent and canopy-like magnetic fields in the solar chromosphere p256

Egidio Landi Degl'Innocenti

doi:10.1038/32603


Tunnelling and zero-point motion in high-pressure ice p258

Magali Benoit, Dominik Marx and Michele Parrinello

doi:10.1038/32609

See also: News and Views by Teixeira


Polarizing energy transfer in photoluminescent materials for display applications p261

Andrea Montali, Cees Bastiaansen, Paul Smith and Christoph Weder

doi:10.1038/32616


Total synthesis of brevetoxin A p264

K. C. Nicolaou, Zhen Yang, Guo-qiang Shi, Janet L. Gunzner, Konstantinos A. Agrios and Peter Gärtner

doi:10.1038/32623


An unusual mid-Pleistocene monsoon period over Africa and Asia p269

M. Rossignol-Strick, M. Paterne, F. C. Bassinot, K.-C. Emeis and G. J. De Lange

doi:10.1038/32631


Abyssal hills formed by stretching oceanic lithosphere p272

W. Roger Buck and Alexei N. B. Poliakov

doi:10.1038/32636

See also: News and Views by Goff


The skull of a relative of the stem-group bird Mononykus p275

Luis M. Chiappe, Mark A. Norell and James M. Clark

doi:10.1038/32642


Common reference frame for neural coding of translational and rotational optic flow p278

D. R. W. Wylie, W. F. Bischof and B. J. Frost

doi:10.1038/32648

See also: News and Views by Hengstenberg


Sniffing and smelling: separate subsystems in the human olfactory cortex p282

N. Sobel, V. Prabhakaran, J. E. Desmond, G. H. Glover, R. L. Goode, E. V. Sullivan and J. D. E. Gabrieli

doi:10.1038/32654


Nocistatin, a peptide that blocks nociceptin action in pain transmission p286

Emiko Okuda-Ashitaka, Toshiaki Minami, Shinro Tachibana, Yoshihiro Yoshihara, Yuji Nishiuchi, Terutoshi Kimura and Seiji Ito

doi:10.1038/32660


Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito p289

O. Billker, V. Lindo, M. Panico, A. E. Etienne, T. Paxton, A. Dell, M. Rogers, R. E. Sinden and H. R. Morris

doi:10.1038/32667

See also: News and Views by Carter & Ranford-Cartwright


Genetic basis and molecular mechanism for idiopathic ventricular fibrillation p293

Qiuyun Chen, Glenn E. Kirsch, Danmei Zhang, Ramon Brugada, Josep Brugada, Pedro Brugada, Domenico Potenza, Angel Moya, Martin Borggrefe, Günter Breithardt, Rocio Ortiz-Lopez, Zhiqing Wang, Charles Antzelevitch, Richard E. O'Brien, Eric Schulze-Bahr, Mark T. Keating, Jeffrey A. Towbin and Qing Wang

doi:10.1038/32675


Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1 p296

Jianke Zhang, Dragana Cado, Ann Chen, Nisha H. Kabra and Astar Winoto

doi:10.1038/32681


Mutations of mitotic checkpoint genes in human cancers p300

Daniel P. Cahill, Christoph Lengauer, Jian Yu, Gregory J. Riggins, James K. V. Willson, Sanford D. Markowitz, Kenneth W. Kinzler and Bert Vogelstein

doi:10.1038/32688

See also: News and Views by Orr-Weaver & Weinberg


Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeast p303

Masaki Mizunuma, Dai Hirata, Kohji Miyahara, Eiko Tsuchiya and Tokichi Miyakawa

doi:10.1038/32695


Human beta-tryptase is a ring-like tetramer with active sites facing a central pore p306

Pedro José Barbosa Pereira, Andreas Bergner, Sandra Macedo-Ribeiro, Robert Huber, Gabriele Matschiner, Hans Fritz, Christian P. Sommerhoff and Wolfram Bode

doi:10.1038/32703


Erratum:  Discovery of a supernova explosion at half the age of the Universe p311

S. Perlmutter, G. Aldering, M. Della Valle, S. Deustua, R. S. Ellis, S. Fabbro, A. Fruchter, G. Goldhaber, A. Goobar, D. E. Groom, I. M. Hook, A. G. Kim, M. Y. Kim, R. A. Knop, C. Lidman, R. G. McMahon, P. Nugent, R. Pain, N. Panagia, C. R. Pennypacker, P. Ruiz-Lapuente, B. Schaefer and N. Walton

doi:10.1038/32711


Retracted Correction:  CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma p311

Ofer Mandelboim, Gideon Berke, Mati Fridkin, Michael Feldman, Miriam Eisenstein and Lea Eisenbach

doi:10.1038/32713


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New on the Market

Genetics and genomics p312

This selection of products includes systems for high-throughput DNA preparation, mutation analysis and fragment screening, a variety of genetics and genomics software, as well as an assortment of probes and labels.
compiled by Brendan Horton from information provided by the manufacturers. For more details, fill in the reader service card bound inside the journal.

doi:10.1038/32715


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