Table of contents


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Opinion

Time to accept realities of bioweapon control p823

The costs of preventing the barbarity of biological warfare are not only financial but also include intrusiveness, at home as well as abroad. There is an urgent need to shoulder those costs to ensure an effective ban.

doi:10.1038/35930


Cloning's confused signals p823

Worries about failure to replicate Dolly are premature but stimulating.

doi:10.1038/35932


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News

Dolly researcher plans further experiments after challenges p825

Declan Butler

doi:10.1038/35934


French agency faces fresh controversy p825

Declan Butler and Olivier de Gandt

doi:10.1038/35937


Genome panel defends researchers' — and families' — interests p826

Meredith Wadman

doi:10.1038/35939


Medical researchers set up UK body to raise public profile p827

Asako Saegusa

doi:10.1038/35941


Japan backs carbon project in shift to applied research p827

Richard Nathan

doi:10.1038/35943


Germany seeks 'non-modified' food label p828

Alison Abbott and Burkhardt Roeper

doi:10.1038/35946


ANZAAS looks to grassroots for relaunch p828

Peter Pockley

doi:10.1038/35949


Ecologists seek flexible protection rules p829

Tony Reichhardt

doi:10.1038/35951


Boost to biodiversity research 'would strengthen US economy' p829

Colin Macilwain

doi:10.1038/35954


US urged to explore accelerator options p830

Colin Macilwain

doi:10.1038/35956


UK nuclear physicists set to lose their privileged funding status p830

Ehsan Masood

doi:10.1038/35958


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News Analysis

Iraq crisis spurs new bioweapons moves p831

Lack of provision in the Biological Weapons Convention for monitoring and verifying compliance has long been a worry. But negotiations for such provision have been given new momentum by recent events in Iraq.

David Dickson

doi:10.1038/35961


Individuals face weapons work indictment p831

David Dickson

doi:10.1038/35963


News in Brief p832

doi:10.1038/35965


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Correspondence

Flow of novel genes for R&D continues p834

David C. U'Prichard, (Chairman, Research and Development)

doi:10.1038/35967


New Zealand science p834

P. M. Hargreaves, President

doi:10.1038/35969


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Commentary

A test for the insurance industry p835

Life insurers claim they stand to lose unless allowed access to applicants' genetic information, but consumers insist such data should remain out of bounds. Could both sides be right?

doi:10.1038/35971


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News and Views

Clouds, contrails and climate p837

John H. Seinfeld

doi:10.1038/35974


Ecology:  Green policies for defence spending p838

Peter D. Moore

doi:10.1038/35977


Molecular physiology:  Key clockwork component cloned p839

Richard W. Tsien

doi:10.1038/35981


Optics:  A time-resolved glimpse of the terahertz glory p841

Philip L. Marston

doi:10.1038/35984


100 and 50 years ago p842

doi:10.1038/35988


Ecology:  Kiss of death p842

Alison Mitchell

doi:10.1038/35990


Protein metabolism:  Slow and fast dietary proteins p843

Gema Frühbeck

doi:10.1038/35993


Neurobiology:  Homeostasis or synaptic plasticity? p845

Yves Frégnac

doi:10.1038/35996


Diabetes:  A signal for beta-cell failure p846

Joseph Avruch

doi:10.1038/35998


Erratum:  Galileo at Jupiter — meetings with remarkable moons p847

doi:10.1038/36001


Erratum: Fixed hotspots gone with the wind p847

doi:10.1038/36003


Daedalus:  Cold porridge p847

David Jones

doi:10.1038/36005


Obituary:  Masaru Ibuka (1908-97) p848

Gerhard Fasol

doi:10.1038/36007


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Art and Science

Latham's life-forms p849

William Latham is working to establish a place for computers in the world of art. He sets the design rules to be followed and his program generates images in a process that could be called a simulation of evolution in action.

Martin Kemp

doi:10.1038/36010


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Scientific Correspondence

Skin immunization made possible by cholera toxin p851

Gregory M. Glenn, Mangala Rao, Gary R. Matyas and Carl R. Alving

doi:10.1038/36014


Rescuing Wolbachia have been overlooked... p852

Kostas Bourtzis, Stephen L. Dobson, Henk R. Braig and Scott L. O'Neill

doi:10.1038/36017


...and discovered on Mount Kilimanjaro p853

Hervé Merçot and Denis Poinsot

doi:10.1038/36021


Cranial surgery dates back to Mesolithic p854

Malcolm C. Lillie

doi:10.1038/36023


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Book Reviews

Celestial calculations p855

William R. Shea reviews Pierre-Simon Laplace (1749-1827): A Life in Exact Science by Charles Coulston Gillispie

doi:10.1038/36027


Figure heads p856

Brian Butterworth reviews The Number Sense: How the Mind Creates Mathematics by Stanislas Dehaene

doi:10.1038/36030


Old embryos and new developments p857

Jonathan Slack reviews Principles of Development by Lewis Wolpert, Rosa Beddington, Jeremy Brookes and Thomas Jessell and Embryology: Constructing the Organism edited by Scott F. Gilbert and Anne M. Raunio

doi:10.1038/36032


The great elusionist p858

Stephen Battersby reviews The Elusive Neutrino: A Subatomic Detective Story by Nickolas Solomey

doi:10.1038/36035


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Article

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7 p859

Jie-Oh Lee, Alicia A. Russo and Nikola P. Pavletich

doi:10.1038/36038


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Letters to Nature

A population of faint galaxies that contribute to the cosmic X-ray background p866

Y. Ueda, T. Takahashi, H. Inoue, T. Tsuru, M. Sakano, Y. Ishisaki, Y. Ogasaka, K. Makishima, T. Yamada, K. Ohta and M. Akiyama

doi:10.1038/36047


An oxygen-rich dust disk surrounding an evolved star in the Red Rectangle p868

L. B. F. M. Waters, C. Waelkens, H. van Winckel, F. J. Molster, A. G. G. M. Tielens, J. Th. van Loon, P. W. Morris, J. Cami, J. Bouwman, A. de Koter, T. de Jong and Th. de Graauw

doi:10.1038/36052


Dephasing in electron interference by a 'which-path' detector p871

E. Buks, R. Schuster, M. Heiblum, D. Mahalu and V. Umansky

doi:10.1038/36057


Two-dimensional ferroelectric films p874

A. V. Bune, V. M. Fridkin, Stephen Ducharme, L. M. Blinov, S. P. Palto, A. V. Sorokin, S. G. Yudin and A. Zlatkin

doi:10.1038/36069


Surface-induced structure formation of polymer blends on patterned substrates p877

Martin Böltau, Stefan Walheim, Jürgen Mlynek, Georg Krausch and Ullrich Steiner

doi:10.1038/36075


Origin of upper-ocean warming and El Niño change on decadal scales in the tropical Pacific Ocean p879

Rong-Hua Zhang, Lewis M. Rothstein and Antonio J. Busalacchi

doi:10.1038/36081


Evidence for pressure-release melting beneath magmatic arcs from basalt at Galunggung, Indonesia p883

T. W. Sisson and S. Bronto

doi:10.1038/36087


Foot posture in a primitive pterosaur p886

J. M. Clark, J. A. Hopson, R. Hernández R., D. E. Fastovsky and M. Montellano

doi:10.1038/36092


Explaining the geographic distributions of sexual and asexual populations p889

Joel R. Peck, Jonathan M. Yearsley and David Waxman

doi:10.1038/36099


Activity-dependent scaling of quantal amplitude in neocortical neurons p892

Gina G. Turrigiano, Kenneth R. Leslie, Niraj S. Desai, Lana C. Rutherford and Sacha B. Nelson

doi:10.1038/36103

See also: News and Views by Frégnac


Molecular characterization of a neuronal low-voltage-activated T-type calcium channel p896

Edward Perez-Reyes, Leanne L. Cribbs, Asif Daud, Antonio E. Lacerda, Jane Barclay, Magali P. Williamson, Margaret Fox, Michele Rees and Jung-Ha Lee

doi:10.1038/36110

See also: News and Views by Tsien


Disruption of IRS-2 causes type 2 diabetes in mice p900

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery, Deborah J. Burks, Jian-Ming Ren, Stephen Previs, Yitao Zhang, Dolores Bernal, Sebastian Pons, Gerald I. Shulman, Susan Bonner-Weir and Morris F. White

doi:10.1038/36116

See also: News and Views by Avruch


Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor p904

Anne E. Corcoran, Andrew Riddell, Danielle Krooshoop and Ashok R. Venkitaraman

doi:10.1038/36122


beta-Chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans p908

Ludwig Wagner, Otto O. Yang, Eduardo A. Garcia-Zepeda, Yimin Ge, Spyros A. Kalams, Bruce D. Walker, Mark S. Pasternack and Andrew D. Luster

doi:10.1038/36129


Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5 p912

Christian Sirrenberg, Maxi Endres, Heike Fölsch, Rosemary A. Stuart, Walter Neupert and Michael Brunner

doi:10.1038/36136


Group II intron splicing in vivo by first-step hydrolysis p915

Mircea Podar, Vi T. Chu, Anna Marie Pyle and Philip S. Perlman

doi:10.1038/36142


X-ray crystal structure of arrestin from bovine rod outer segments p918

Joachim Granzin, Ursula Wilden, Hui-Woog Choe, Jörg Labahn, Bianca Krafft and Georg Büldt

doi:10.1038/36147


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New on the Market

At the flick of a molecular switch p922

This week's product update features tools for the cell biologist, including electroporation and transfection systems, transcription and translation kits, new fluorescent markers and reagents for neuroscience.
compiled by Brendan Horton from information provided by the manufacturers.

doi:10.1038/36154


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