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Nature 391, 845-846 (26 February 1998) | doi:10.1038/35996
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Paleobiologist / Biogeochemist
- University of Cincinnati
- Cincinnati, Ohio, USA
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Neurobiology: Homeostasis or synaptic plasticity?
Yves Frégnac1
Almost 50 years ago, Hebb1 proposed that during development, learning and perception, correlated activity induces long-lasting strengthening in synaptic transmission. Remarkably, however, neurobiologists inspired by Hebb's principle have sought only one side of the regulatory process — that is, synapse-specific changes in synaptic strengths.
- Yves Frégnac is in the Equipe Cognisciences, Institut Alfred Fessard, CNRS, 91198 Gif sur Yvette, France.
e-mail: Email: Yves.Fregnac@iaf.cnrs.gif.fr
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