Table of contents
Volume 389 Number 6653 pp767-889
Opinion
Spanish science is still at risk p767
Although it may well be the only country in Europe to increase research spending next year, Spain still faces the loss of outstanding researchers. Both the government and universities need to make difficult choices.
doi:10.1038/39660
Light in dark places p767
Despite cultural differences, countries face common challenges in confronting new biomedical advances.
doi:10.1038/39662
News
Fusion researchers seek US role as partner in EU's JET facility p769
Colin Macilwain
doi:10.1038/39664
Cassini mission blasts off for Saturn p769
Tony Reichhardt
doi:10.1038/39666
Nobel prizes honour atom-trappers ... p770
Philip Ball
doi:10.1038/39669
... and biologists' work on protein energy converters p771
Christopher Surridge
doi:10.1038/39674
Faulty solar panel jeopardizes Mars mapping project p772
Tony Reichhardt
doi:10.1038/39679
Genome research strategy splits Japanese scientists p772
Asako Saegusa
doi:10.1038/39681
Launch of Lunar Prospector delayed p772
Tony Reichhardt
doi:10.1038/39683
Spanish budget raises postdoc job hopes p773
Alison Abbott
doi:10.1038/39685
University rectors join task force on reforms p773
Alison Abbott
doi:10.1038/39688
Genome study maps chemical sensitivity p774
Meredith Wadman
doi:10.1038/39690
Diversity project 'does not merit federal funding' p774
Colin Macilwain
doi:10.1038/39693
'Bioethics needs better input from public' p775
Declan Butler
doi:10.1038/39695
Nobel backing for alternative health journal p775
Meredith Wadman
doi:10.1038/39698
News in Brief p776
doi:10.1038/39700
erratum Axel Kahn p776
doi:10.1038/39702
Correspondence
How to make Kyoto a success p777
David G. Victor, Gordon J. MacDonald and Michael Jefferson
doi:10.1038/39704
All sorts of authorship p777
Eugene Garfield
doi:10.1038/39706
Pest adaptation p778
Bruce Tabashnik
doi:10.1038/39708
Value for money in US laboratories p778
Robert D. Nicholls
doi:10.1038/39710
A probable paradox p779
P. T. Landsberg and J. N. Dewynne
doi:10.1038/39712
Harried hen harriers p780
Chris Mead
doi:10.1038/39714
Greenpeace and BP p780
Peter Melchett
doi:10.1038/39716
Natural selection and the sex ratio p780
A. W. F. Edwards
doi:10.1038/39718
Commentary
Testing the nuclear test-ban treaty p781
A recent earthquake near a former Soviet nuclear test site has tested mechanisms for monitoring the test-ban treaty. Technical systems passed with flying colours, but relevant US agencies could have done better.
doi:10.1038/39720
News and Views
Some like it hot: spicing up ion channels p783
David E. Clapham
doi:10.1038/39724
100 and 50 years ago p784
doi:10.1038/39727
Sensors New age crystals p784
David G. Grier
doi:10.1038/39729
Genomic imprinting Disomy and disease resolved? p785
Nicholas Hastie
doi:10.1038/39732
Avoided object p787
doi:10.1038/39735
Atmospheric chemistry A bad winter for Arctic ozone p788
Richard Stolarski
doi:10.1038/39737
Fluid dynamics How coffee leaves its mark p788
Philip Ball
doi:10.1038/39740
Developmental neurobiology Neurotrophins moving forward p789
John V. Heymach, Jr and Barbara A. Barres
doi:10.1038/39743
Synapses Plastic plasticity p791
John H. Byrne
doi:10.1038/39746
Earth science Probe of a plate interior p792
Bruce Yardley
doi:10.1038/39750
Daedalus Floating on nothing p793
David Jones
doi:10.1038/39753
Obituary Hans Jurgen Eysenck (1916-97) p794
Jeffrey Gray
doi:10.1038/39755
News and Views Feature
Prion research: the next frontiers p795
At the beginning of this month, Stanley Prusiner of the University of California, San Francisco, was awarded the Nobel Prize in Physiology or Medicine for his work on the infectious agent that causes spongiform encephalopathies _ the prion. His 'protein-only' theory now has many advocates, and the advances that have been made, the questions that remain and the ways in which these could be addressed are discussed in this feature.
Adriano Aguzzi and Charles Weissmann
doi:10.1038/39758
Art and Science
Lisa's laws p799
Leonardo da Vinci is almost as well remembered for his scientific investigations as for his paintings and sculpture. His work as an artist was informed by his insight into science, as his system of 'natural laws' demonstrates.
Martin Kemp
doi:10.1038/39762
Scientific Correspondence
Sex on the brain p801
S. Marc Breedlove
doi:10.1038/39764
First paragraph | Full Text | PDF (113K)
Antibiotic resistance spread in food p801
Vincent Perreten, Franziska Schwarz, Luana Cresta, Marianne Boeglin, Gottfried Dasen and Michael Teuber
doi:10.1038/39767
First paragraph | Full Text | PDF (113K)
Targeted disruption in Arabidopsis p802
Sherry A. Kempin, Sarah J. Liljegren, Laura M. Block, Steven D. Rounsley, Martin F. Yanofsky and Eric Lam
doi:10.1038/39770
First paragraph | Full Text | PDF (115K)
Speciation in the open ocean p803
Masaki Miya and Mutsumi Nishida
doi:10.1038/39774
First paragraph | Full Text | PDF (123K)
Extraterrestrial handedness p804
Stephen F. Mason
doi:10.1038/39777
First paragraph | Full Text | PDF (109K)
Book Reviews
Bringing order to mental disorders p805
Roy Porter
doi:10.1038/39779
Masked Baule p805
doi:10.1038/39781
Where has the billion trillion gone? p806
I. J. Good
doi:10.1038/39784
Body language p806
doi:10.1038/39786
Toy review Smaller, cheaper, more plasticky p807
Stephen Battersby
doi:10.1038/39789
Dangerous liaisons p807
Jack Cohen
doi:10.1038/39792
Sun, sea and life p808
Egil Sakshaug
doi:10.1038/39794
Articles
Transactivation of Igf2 in a mouse model of Beckwith–Wiedemann syndrome p809
Fang-Lin Sun, Wendy L. Dean, Gavin Kelsey, Nicholas D. Allen and Wolf Reik
doi:10.1038/39797
Abstract | Full Text | PDF (367K)
The capsaicin receptor: a heat-activated ion channel in the pain pathway p816
Michael J. Caterina, Mark A. Schumacher, Makoto Tominaga, Tobias A. Rosen, Jon D. Levine and David Julius
doi:10.1038/39807
Abstract | Full Text | PDF (606K)
Letters to Nature
Ambient acoustic imaging in helioseismology p825
Hsiang-Kuang Chang, Dean-Yi Chou, Barry LaBonte and the TON Team
doi:10.1038/39822
First paragraph | Full Text | PDF (359K)
Capillary flow as the cause of ring stains from dried liquid drops p827
Robert D. Deegan, Olgica Bakajin, Todd F. Dupont, Greb Huber, Sidney R. Nagel and Thomas A. Witten
doi:10.1038/39827
First paragraph | Full Text | PDF (342K)
Polymerized colloidal crystal hydrogel films as intelligent chemical sensing materials p829
John H. Holtz and Sanford A. Asher
doi:10.1038/39834
First paragraph | Full Text | PDF (290K)
Solvent-assisted proton transfer in catalysis by zeolite solid acids p832
James F. Haw, Teng Xu, John B. Nicholas and Patrick W. Goguen
doi:10.1038/39843
First paragraph | Full Text | PDF (302K)
Prolonged stratospheric ozone loss in the 1995–96 Arctic winter p835
Markus Rex, Neil R. P. Harris, Peter von der Gathen, Ralph Lehmann, Geir O. Braathen, Eberhard Reimer, Alexander Beck, Martyn P. Chipperfield, Reimond Alfier, Marc Allaart, Fiona O'Connor, Horst Dier, Valery Dorokhov, Hans Fast, Manuel Gil, Esko Kyrö, Zenobia Litynska, Ib Steen Mikkelsen, Mike G. Molyneux, Hideaki Nakane, Justus Notholt, Markku Rummukainen, Pierre Viatte and John Wenger
doi:10.1038/39849
First paragraph | Full Text | PDF (348K)
Timing of the Ethiopian flood basalt event and implications for plume birth and global change p838
C. Hofmann, V. Courtillot, G. Féraud, P. Rochette, G. Yirgu, E. Ketefo and R. Pik
doi:10.1038/39853
First paragraph | Full Text | PDF (290K)
Vanadium partitioning and the oxidation state of Archaean komatiite magmas p842
Dante Canil
doi:10.1038/39860
First paragraph | Full Text | PDF (299K)
Spatial invariance of visual receptive fields in parietal cortex neurons p845
Jean-René Duhamel, Frank Bremmer, Suliann BenHamed and Werner Graf
doi:10.1038/39865
First paragraph | Full Text | PDF (371K)
False perception of motion in a patient who cannot compensate for eye movements p849
Thomas Haarmeier, Peter Thier, Marc Repnow and Dirk Petersen
doi:10.1038/39872
First paragraph | Full Text | PDF (434K)
Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth p852
M. L. Condic and P. C. Letourneau
doi:10.1038/39878
First paragraph | Full Text | PDF (440K)
Anterograde transport of brain-derived neurotrophic factor and its role in the brain p856
C. Anthony Altar, Ning Cai, Tricia Bliven, Melissa Juhasz, James M. Conner, Ann L. Acheson, Ronald M. Lindsay and Stanley J. Wiegand
doi:10.1038/39885
First paragraph | Full Text | PDF (439K)
Metaplasticity at identified inhibitory synapses in Aplysia p860
Thomas M. Fischer, Diana E. J. Blazis, Naomi A. Priver and Thomas J. Carew
doi:10.1038/39892
First paragraph | Full Text | PDF (473K)
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene p865
Derek D. Yang, Chia-Yi Kuan, Alan J. Whitmarsh, Mercedes Rinócn, Timothy S. Zheng, Roger J. Davis, Pasko Rakic and Richard A. Flavell
doi:10.1038/39899
First paragraph | Full Text | PDF (512K)
Identification and characterization of the vesicular GABA transporter p870
Steven L. McIntire, Richard J. Reimer, Kim Schuske, Robert H. Edwards and Erik M. Jorgensen
doi:10.1038/39908
First paragraph | Full Text | PDF (547K)
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours p876
N. Dahmane, J. Lee, P. Robins, P. Heller and A. Ruiz i Altaba
doi:10.1038/39918
First paragraph | Full Text | PDF (561K)
A SNARE involved in protein transport through the Golgi apparatus p881
Stephen Loucian Lowe, Frank Peter, V. Nathan Subramaniam, Siew Heng Wong and Wanjin Hong
doi:10.1038/39923
First paragraph | Full Text | PDF (406K)
Crystallographic structure of the T domain–DNA complex of the Brachyury transcription factor p884
Christoph W. Müller and Bernhard G. Herrmann
doi:10.1038/39929
First paragraph | Full Text | PDF (609K)
New on the Market
Neuroscience mardi gras p889
With some 25,000 participants descending on New Orleans, attendees of the Society for Neuroscience meeting must be wondering how to cover such an event. Here are some ideas on new products that may be on exposition.
compiled by Brendan Horton from information provided by the manufacturers.
doi:10.1038/39938