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Nature 389, 668-669 (16 October 1997) | doi:10.1038/39453
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Molecular Biologists and Biochemists
- University of Minnesota
- Minnesota, USA
Faculty - Plant Cellular & Molecular Biology, Molecular Genetics & the Plant Molecular Biology / Biotechnology Program
- The Ohio State University
- Columbus, Ohio
Developmental neurobiology: Unscrambling a disabled brain
André M. Goffinet1
The orderly development of neurons in the mammalian brain is a conundrum that defies imagination: the billions of neurons that are generated around the cerebral ventricles must migrate through the tissue to find their destination, before forming exquisite cell patterns. The formation of these patterns is abnormal in mice with the reeler phenotype, showing that it is controlled by the reeler, scrambler and, probably, several other genes.
- André M. Goffinet is in the Département de Physiologie Humaine, Facultés Universitaires Notre-Dame de la Paix, 61 rue de Bruxelles, B-5000 Namur, Belgium.
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