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Nature 389, 437-438 (2 October 1997) | doi:10.1038/38876

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Human BSE

Jeffrey Almond1 & John Pattison2

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Two sets of studies, using different approaches, provide convincing evidence that the new variant of Creutzfeldt — Jakob disease is caused by the agent that is responsible for BSE in cattle. But they cannot tell us anything about the future number of cases of this variant disease.

On 20 March 1996 the UK government announced that a distinct variant of Creutzfeldt-Jakob disease (vCJD) had occurred in ten people in the United Kingdom over the previous 14 months1. Like CJD, the variant form results in brain damage and death; but it is pathologically and clinically distinct, not least in afflicting comparatively young people.

  1. Jeffrey Almond is in the School of Animal and Microbial Sciences, University of Reading, Reading RG6 6AJ, UK.
  2. John Pattison is in the Medical School, University College London, Gower Street, London WC1E 6BT, UK.