Table of contents


Top

Opinion

Referendum's challenge to transgenic research p103

The Swiss have embarked on a national debate about the use of transgenic animals, threatening devastation of biological science and industry in their country. Are they a barometer of wider public antipathy?

doi:10.1038/38052


Quantity is not enough p103

Japan's scientifically weaker neighbours are outperforming it in the pursuit of quality.

doi:10.1038/38054


Top

News

Gene therapist accused of fraud to seek redress in German court p105

Quirin Schiermeier

doi:10.1038/38056


Accidents prompt Los Alamos closure p105

Sally Lehrman

doi:10.1038/38059


Santa Fe centre seeks second wind p106

Colin Macilwain

doi:10.1038/38061


Japan struggles towards emissions targets p107

Robert Triendl

doi:10.1038/38064


'Slick' new company eyes medical diagnostics market p107

Sally Lehrman

doi:10.1038/38067


Respite for NASA's troubled data system p108

Tony Reichhardt

doi:10.1038/38069


Earth scientists count the cost of loss of Lewis demo satellite p108

Tony Reichhardt

doi:10.1038/38072


UK reaffirms commitment to independent food agency p109

Ehsan Masood

doi:10.1038/38074


DNA fingerprinting evidence questioned p109

K. S. Jayaraman

doi:10.1038/38077


Australia plans new research reactor but no reprocessing p109

Peter Pockley

doi:10.1038/38079


Bidder for Brookhaven centre bails out p110

Colin Macilwain

doi:10.1038/38081


US DoE laboratories need 'compelling' missions p111

David Kramer

doi:10.1038/38084


News in Brief p112

doi:10.1038/38086


Top

Briefing

Western research assessment meets Asian cultures p113

The emerging economies of the Pacific Rim of Asia are applying research assessment to boost the quantity and quality of their research, while Japan is just awakening to the need for such processes. But cultural obstacles have led to diverse approaches across the region.

doi:10.1038/38088


Top

Correspondence

Thalidomide is not a mutagen p118

John Ashby

doi:10.1038/38096


Contaminated water p118

Lynn Jones

doi:10.1038/38098


No politics, please p118

David Gershon

doi:10.1038/38100


As others see us p118

Michael Gro

doi:10.1038/38102


Top

News and Views

A shot in the arm for fractional charge p119

Charles L. Kane and Matthew P. A. Fisher

doi:10.1038/38104


E. coligenome sequence:  A blueprint for life p120

E. Richard Moxon and Christopher F. Higgins

doi:10.1038/38107


Functions for orphan genes p120

E. Richard Moxon and Christopher F. Higgins

doi:10.1038/38110


Materials science:  Percolation frustrated p121

Robert W. Cahn

doi:10.1038/38113


Tumour-suppressor genes:  Killer in search of a motive? p122

Bruce Clurman and Mark Groudine

doi:10.1038/38116


Defining tumour-suppressor genes p123

Bruce Clurman and Mark Groudine

doi:10.1038/38119


100 and 50 years ago p125

doi:10.1038/38121


Solar System:  Pipelines to the planets p125

Donald M. Hunten

doi:10.1038/38123


Agriculture:  In search of perennial solutions p126

Stuart L. Pimm

doi:10.1038/38126


Quantum mechanics:  Statistics given a spin p127

Jason Twamley

doi:10.1038/38130


Eukaryotic ribosomal RNA:  Guides to 95 new angles p129

B. Edward H. Maden

doi:10.1038/38134


Ecology:  Venus firefly traps p130

Allison Mitchell

doi:10.1038/38138


Erratum:  HIV-cell fusion: The viral mousetrap p131

doi:10.1038/38141


Daedalus:  Droplets of gas p131

David Jones

doi:10.1038/38143


Obituary:  Eugene M. Shoemaker (1928-97) p132

Thomas J. Ahrens

doi:10.1038/38145


Top

Scientific Correspondence

Middle-aged mothers live longer p133

Thomas T. Perls, Laura Alpert and Ruth C. Fretts

doi:10.1038/38148


Has BCG attenuated to impotence? p133

Marcel A. Behr and Peter M. Small

doi:10.1038/38151


Inhibition of carcinogenesis by tea p134

Chung S. Yang

doi:10.1038/38154


A plant cold-induced uncoupling protein p135

Maryse Laloi, Mathieu Klein, Jörg W. Riesmeier, Bernd Müller-Röber, Christophe Fleury, Frédéric Bouillaud and Daniel Ricquier

doi:10.1038/38156


Caffeine alters plasma adenosine levels p136

Lydia A. Conlay, Jeffrey A. Conant, Fred deBros and Richard Wurtman

doi:10.1038/38160


Top

New Journals

Plugging into electronic journals p137

James Porteous

doi:10.1038/38164


Highways and byways in biology p139

Lisa Satterwhite

doi:10.1038/38167


Journals index p139

doi:10.1038/38170


New Journals review 1997 p140

doi:10.1038/38173


More development than advertised p140

Gary L. Westbrook reviews MCN: Molecular and Cellular Neuroscience Editors-in-chief Greg Lemke and Frank S. Walsh

doi:10.1038/38175


Fundamentals of fertility p141

Roger Gosden reviews Molecular Human Reproduction Editor-in-chief Robert G. Edwards

doi:10.1038/38177


Cells in distress p141

Helen Saibil and Peter Lund review Cell Stress and Chaperones Editor-in-chief Lawrence E. Hightower

doi:10.1038/38180


Mind and molecules p141

Leslie Iversen reviews Molecular Psychiatry Editor Julio Licinio

doi:10.1038/38182


Hearing and balance p142

S. M. Khanna reviews Audiology and Neuro-Otology: Basic Research and Clinical Applications Editor-in-chief Manfried Hoke

doi:10.1038/38184


Brain terrain p142

Jonathan D. Cohen reviews NeuroImage: A Journal of Brain Function Editors-in-chief Arthur W. Toga, Richard S. J. Frackowiak and John C. Mazziotta

doi:10.1038/38186


Lateral thinking p142

Dale Purves and Leonard E. White review Laterality Editors Michael Corballis, Chris McManus and Michael Peters

doi:10.1038/38189


Green shoots p143

Axel Brennicke reviews Trends in Plant Sciences Editor Hugh Blackbourn

doi:10.1038/38191


On the move p143

Peter D. Moore reviews Global Change Biology Editor-in-chief Steve Long

doi:10.1038/38194


Global control p144

Lawrence M. Hanks reviews Integrated Pest Management Reviews Editor David Dent

doi:10.1038/38196


Find that molecule p144

Neal S. Burres reviews Journal of Biomolecular Screening: The Official Journal of the Society for Biomolecular Screening Editor Mark Crawford

doi:10.1038/38199


A suitable treatment p144

Robin A. Weiss reviews Antiviral Therapy Editors-in-chief Joep M. A. Lange and Douglas D. Richman

doi:10.1038/38202


Out of Africa p145

Robert Desowitz reviews Tropical Medicine and International Health: A European Journal Coordinating editor D. J. Bradley

doi:10.1038/38204


Development ladder p145

Ziauddin Sardar reviews Science, Technology and Society: An International Journal Devoted to the Developing World by V. V. Krishna and Roland Waast

doi:10.1038/38207


What's it all worth? p146

Neil Adger reviews Environment and Development Economics Editor Charles Perrings

doi:10.1038/38210


Physics matters p146

David Goodstein and Judith Goodstein review Studies in History and Philosophy of Modern Physics: Part B of Studies in History and Philosophy of Science Editors Jeremy Butterfield,, Peter Gallison and Michael Redhead

doi:10.1038/38213


Opinions in science? p147

Donald W. Murphy reviews Current Opinions in Solid State and Materials Science Editors Anthony K. Cheetham, Hiroo Inokuchi and John Meurig Thomas

doi:10.1038/38215


Spice of life p147

R. J. P. Williams reviews JBIC: Journal of Biological Inorganic Chemistry Editor-in-chief Ivano Bertini

doi:10.1038/38218


Bright spark p148

Michael Rowan-Robinson reviews New Astronomy: An International, Electronic Journal in Astronomy and Astrophysics Editors Donald C. Backeret al.

doi:10.1038/38220


Journal reincarnate p148

Duncan Steel reviews Astronomy and Geophysics: The Journal of the Royal Astronomical Society Editor Sue Bowler

doi:10.1038/38223


Top

Progress

Regulation of transcription by proteins that control the cell cycle p149

Brian D. Dynlacht

doi:10.1038/38225


Top

Article

Global vegetation change through the Miocene/Pliocene boundary p153

Thure E. Cerling, John M. Harris, Bruce J. MacFadden, Meave G. Leakey, Jay Quade, Vera Eisenmann and James R. Ehleringer

doi:10.1038/38229


Top

Letters to Nature

External supply of oxygen to the atmospheres of the giant planets p159

H. Feuchtgruber, E. Lellouch, T. de Graauw, B. Bézard, T. Encrenaz and M. Griffin

doi:10.1038/38236


Direct observation of a fractional charge p162

R. de-Picciotto, M. Reznikov, M. Heiblum, V. Umansky, G. Bunin and D. Mahalu

doi:10.1038/38241


Application of scanning SQUID petrology to high-pressure materials science p164

Bruce A. Scott, John R. Kirtley, David Walker, Bai-Hao Chen and Yanhui Wang

doi:10.1038/38249


Smectic ordering in solutions and films of a rod-like polymer owing to monodispersity of chain length p167

Seungju M. Yu, Vincent P. Conticello, Guanghui Zhang, Christoph Kayser, Maurille J. Fournier, Thomas L. Mason and David A. Tirrell

doi:10.1038/38254


Mineral control of soil organic carbon storage and turnover p170

Margaret S. Torn, Susan E. Trumbore, Oliver A. Chadwick, Peter M. Vitousek and David M. Hendricks

doi:10.1038/38260


Eclogite xenoliths in west African kimberlites as residues from Archaean granitoid crust formation p173

Hugh Rollinson

doi:10.1038/38266


Stochastic seasonality and nonlinear density-dependent factors regulate population size in an African rodent p176

Herwig Leirs, Nils Chr. Stenseth, James D. Nichols, James E. Hines, Ron Verhagen and Walter Verheyen

doi:10.1038/38271


Functional relevance of cross-modal plasticity in blind humans p180

Leonardo G. Cohen, Pablo Celnik, Alvaro Pascual-Leone, Brian Corwell, Lala Faiz, James Dambrosia, Manabu Honda, Norihiro Sadato, Christian Gerloff, M. Dolores Catala´ and Mark Hallett

doi:10.1038/38278


Defective platelet activation in Galphaq-deficient mice p183

Stefan Offermanns, Christopher F. Toombs, Yi-Hui Hu and Melvin I. Simon

doi:10.1038/38284


Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiPl p187

Kumaravel Somasundaram, Hongbing Zhang, Yi-Xin Zeng, Yariv Houvras, Yi Peng, Hongxiang Zhang, Gen Sheng Wu, Jonathan D. Licht, Barbara L. Weber and Wafik S. El-Deiry

doi:10.1038/38291


p73 is a human p53-related protein that can induce apoptosis p191

Christine A. Jost, Maria C. Marin and William G. Kaelin Jr

doi:10.1038/38298


Steroid receptor coactivator-1 is a histone acetyltransferase p194

Thomas E. Spencer, Guido Jenster, Mark M. Burcin, C. David Allis, Jianxin Zhou, Craig A. Mizzen, Neil J. McKenna, Sergio A. Onate, Sophia Y. Tsai, Ming-Jer Tsai and Bert W. O'Malley

doi:10.1038/38304


Molecular mechanics of calcium–myristoyl switches p198

James B. Ames, Rieko Ishima, Toshiyuki Tanaka, Jeffrey I. Gordon, Lubert Stryer and Mitsuhiko Ikura

doi:10.1038/38310


Arrangement of rhodopsin transmembrane alpha-helices p203

Vinzenz M. Unger, Paul A. Hargrave, Joyce M. Baldwin and Gebhard F. X. Schertler

doi:10.1038/38316


Surface of bacteriorhodopsin revealed by high-resolution electron crystallography p206

Yoshiaki Kimura, Dmitry G. Vassylyev, Atsuo Miyazawa, Akinori Kidera, Masaaki Matsushima, Kaoru Mitsuoka, Kazuyoshi Murata, Teruhisa Hirai and Yoshinori Fujiyoshi

doi:10.1038/38323


erratum:  Cofilin promotes rapid actin filament turnover in vivo p211

Pekka Lappalainen and David G. Drubin

doi:10.1038/38330


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