Figures and Tables
From the following article:
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
Marina Cella, Anneke Engering, Valerie Pinet, Jean Pieters and Antonio Lanzavecchia
Nature 388, 782-787(21 August 1997)
Figure 1
Increased expression of surface and total class II molecules in DC stimulated with LPS or TNF-
.
Figure 2
Extensive internalization and recycling of MHC class II molecules in immature DC is progressively lost together with endocytic activity following maturation.
Full size figure and legend (120K)
Figure 3
Immature DC can efficiently load antigenic peptides on both recycling and newly synthesized MHC class II molecules.
Full size figure and legend (123K)
Figure 4
Transient upregulation of MHC class II synthesis in maturing DC.
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Figure 5
Maturation increases generation of SDS-stable class II dimers containing antigenic peptides.
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Figure 6
Maturation stimuli increase the half-life of class II molecules from 
10 to >100 hours.
Figure 7
Maturation allows DC to maintain memory of antigens encountered.
Full size figure and legend (75K)