Table of contents


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Opinion

Flawed understanding of the scientific process p607

Scientific robustness — not certainty — is the key to good environmental regulation. Only when this is recognized will debates about the soundness of scientific advice or access to data be properly resolved.


Taking on the barons p607

Italy must grasp a unique chance to reform its grant system before the window of opportunity closes.


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News

Fight over Italian research policy threatens chance for reform p609

Alison Abbott


Government considers plans to create biomedical research institute p609

Alison Abbott


Universities rally against cuts in Pentagon-funded research p610

Colin Macilwain


US to tighten protection of medical data p611

Meredith Wadman


After Dolly, meet Gene, the cloned calf p611


Pathfinder probes the weather on Mars p612

Stephen Battersby


'Neutral' mechanism sought to fund environmental research p612

Tony Reichhardt


Independence, but no Nobel winners for India since then p613

K. S. Jayaraman


Make marijuana research easier, panel urges NIH p613

Sally Lehrman


Greenhouse talks edge towards targets p614

Quirin Schiermeier and Robert Triendl


Head of French leukaemia inquiry quits after partisan remarks p614

Eric Glover


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News Analysis

Japan tightens focus in space research p615

Cuts in Japan's space programme indicate a shift towards users' needs, rather than providing broad-based support for space technology.

Robert Triendl


News in Brief p616


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Correspondence

A permanent decline in oil production? p618

Hendrik S. Houthakker and Craig Bond Hatfield


Russian science misrepresented p618

Eugen F. Makarov


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Commentary

What cannot be said in science p619

The scientific enterprise is full of experts on specialist areas but woefully short of people with a unified world-view. This state of affairs can only inhibit progress, and could threaten political and financial support for research.


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News and Views

Will solid hydrogen ever be a metal? p621

Peter P. Edwards and Friedrich Hensel


Evolutionary biology:  Even-toed fingerprints on whale ancestry p622

Michel C. Milinkovitch and J. G. M. Thewissen


100 and 50 years ago p623


Adenosine receptors:  Knockouts anxious for new therapy p624

Solomon H. Snyder


Atmospheric chemistry:  Ozone clouds over the Atlantic p625

Paul Crutzen and Mark Lawrence


Immunotherapy:  Fusion induces tumour rejection p626

Ian Hart and Camilo Colaco


Biodiversity:  Global change through invasion p627

Gábor L. Lövei


Acoustics:  Unwanted and wanted sound p628

Thomas D. Rossing


LDL-receptor structure:  Calcium cages, acid baths and recycling receptors p629

Michael S. Brown, Joachim Herz and Joseph L. Goldstein


Daedalus:  Command performance p630

David Jones


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Scientific Correspondence

Framboidal pyrites in antique books p631

Javier Garcia-Guinea, Jesus Martinez-Frias, Rafael Gonzalez-Martin and Luis Zamora


Intercropping increases parasitism of pests p631

Z. R. Khan, K. Ampong-Nyarko, P. Chiliswa, A. Hassanali, S. Kimani, W. Lwande, W. A. Overholt, W. A. Overholt, J. A. Picketta, L. E. Smart and C. M. Woodcock


Stochastic resonance at the single-cell level p632

R. Dean Astumian, R. K. Adair and James C. Weaver


Reply:  Stochastic resonance at the single-cell level p633

Sergey M. Bezrukov and Igor Vodyanoy


Sequence-specific RNA binding by Bicoid p634

Siu-Kwong Chan and Gary Struhl


Correction:  Metallothionein in snail CD and Cu metabolism p634


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Book Reviews

I'll be judge, I'll be jury p635

Sheila Jasanoff


On the horns of a dilemma p636

Brian Bertram


Motion of the heavens p636

Jacques Laskar


Film review:  Aliens, lies and videotape p637

Leslie Sage is an assistant editor of Nature.


Outdoor man p638


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Review

Fossils, genes and the evolution of animal limbs p639

Neil Shubin, Cliff Tabin and Sean Carroll


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Letters to Nature

Deep winds on Jupiter as measured by the Galileo probe p649

David H. Atkinson, Andrew P. Ingersoll and Alvin Seiff


Wind speeds measured in the deep jovian atmosphere by the Galileo probe accelerometers p650

A. Seiff, R. C. Blanchard, T. C. D. Knight, G. Schubert, D. B. Kirk, D. Atkinson, J. D. Mihalov and R. E. Young


Spontaneous polarization in dense hydrogen p652

B. Edwards and N. W. Ashcroft


Resonant pattern formation in achemical system p655

Valery Petrov, Qi Ouyang and Harry L. Swinney


Plasticity and avalanche behaviour in microfracturing phenomena p658

Stefano Zapperi, Alessandro Vespignani and H. Eugene Stanley


Ozone-rich transients in the upper equatorial Atlantic troposphere p661

K. Suhre, J.-P. Cammas, P. Nédelec, R. Rosset, A. Marenco and H. G. J. Smit


Conspecific sperm precedence in Drosophila p663

Catherine S. C. Price


Molecular evidence from retroposons that whales form a clade within even-toed ungulates p666

Mitsuru Shimamura, Hiroshi Yasue, Kazuhiko Ohshima, Hideaki Abe, Hidehiro Kato, Toshiya Kishiro, Mutsuo Goto, Isao Munechika and Norihiro Okada


Formation of olfactory memories mediated by nitric oxide p670

K. M. Kendrick, R. Guevara-Guzman, J. Zorrilla, M. R. Hinton, K. D. Broad, M. Mimmack and S. Ohkura


Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor p674

Catherine Ledent, Jean-Marie Vaugeois, Serge N. Schiffmann, Thierry Pedrazzini, Malika El Yacoubi, Jean-Jacques Vanderhaeghen, Jean Costentin, John K. Heath, Gilbert Vassart and Marc Parmentier


Altered pain perception and inflammatory response in mice lacking prostacyclin receptor p678

Takahiko Murata, Fumitaka Ushikubi, Toshiyuki Matsuoka, Masakazu Hirata, Atsushi Yamasaki, Yukihiko Sugimoto, Atsushi Ichikawa, Yoshiya Aze, Takashi Tanaka, Nobuaki Yoshida, Akinori Ueno, Sachiko Oh-ishi and Shuh Narumiya


Crustacean appendage evolution associated with changes in Hox gene expression p682

Michalis Averof and Nipam H. Patel


Recruitment of functional GABAA receptors to postsynaptic domains by insulin p686

Q. Wan, Z. G. Xiong, H. Y. Man, C. A. Ackerley, J. Braunton, W. Y. Lu, L. E. Becker, J. F. MacDonald and Y. T. Wang


Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module p691

Deborah Fass, Stephen Blacklow, Peter S. Kim and James M. Berger


Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP p693

Katrin Rittinger, Philip A. Walker, John F. Eccleston, Kurshid Nurmahomed, Darerca Owen, Ernest Laue, Steven J. Gamblin and Stephen J. Smerdon


Correction:  A new chromosomal protein essential for mitotic spindle assembly p697

Jing-Ping Yeo, Frank Alderuccio and Ban-Hock Toh


Correction:  RNA recognition and translational regulation by a homeodomain protein p697

Josh Dubnau and Gary Struhl


Erratum:  Synapse specificity of long-term potentiation breaks down at short distances p698

Florian Engert and Tobias Bonhoeffer


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