Table of contents


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Opinion

When steady state is no longer good enough p501

The US Department of Energy will have to build something soon if it is to retain its role as provider of state-of-the-art scientific facilities. It should draw up a realistic medium-term plan for facility construction.


Double trouble p501

Unesco should think again before endorsing an outright condemnation of human cloning.


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News

Delays at Brookhaven reactor worsen US 'neutron drought' p503

Colin Macilwain


Women researchers take on 'old boys' network' p504

Colin Macilwain


Backing for anti-cloning bill reopens embryo debate p505

Meredith Wadman


Japan leads rise in research budgets in OECD countries p505


US grants support teraflop computing simulations p506

David Kramer


Endangered species bill faces battle against property lobby p506

Tony Reichhardt


Modest increase proposed for EU research budget p506

Alison Abbott


New DFG head vows to back Germany's young scientists — and genetics research p507

Alison Abbott


Energy laboratories to open joint DNA sequence 'factory' p507

Sally Lehrman


Unesco text will target gene techniques p508

Meredith Wadman


Australian policy review backs huge cuts in research funding p509

Peter Pockley


News in Brief p510


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Correspondence

Cloning, dignity and ethical reasoning p511

David Shapiro


Back to basics p511

Jukka Heinonen


Alphabetical orders p511

Tom Tregenza


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Commentary

Turning back the harmful red tide p513

Harmful algal blooms are a serious and increasing problem in marine waters, yet scientists and funding agencies have been slow to investigate possible control strategies.


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News and Views

A bug with excess gastric avidity p515

Russell F. Doolittle


Asteroids:  Eros's extended family p516

Richard P. Binzel


Mycorrhizal fungi:  The ties that bind p517

David Read


Fluid dynamics:  A fractal world of cloistered waves p518

Peter G. Baines


Signal transduction:  IkappaB kinase all zipped up p519

Alain Israë


100 and 50 years ago p520


Climate change:  Is the ocean at the helm? p521

Mike McCartney


Carbon cycle:  Inside the black box p522

Richard Norby


Erratum:  How one Galaxy can be a cluster p523


Daedalus:  Counting on the truth p523

David Jones


Obituary:  Drummond Hoyle Matthews (1931-97) p524

Robert S. White


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Scientific Correspondence

Acoustic alarms reduce porpoise mortality p525

Scott D. Kraus, Andrew J. Read, Andrew Solow, Ken Baldwin, Trevor Spradlin, Eric Anderson and John Williamson


UK birds are laying eggs earlier p526

Humphrey Q. P. Crick, Caroline Dudley, David E. Glue and David L. Thomson


CO2 increases oceanic primary production p526

Mette Hein and Kaj Sand-Jensen


Structural biology and phylogenetic estimation p527

Gavin J. P. Naylor and Wesley M. Brown


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Book Reviews

The planetary piggy bank p529

Mary Power reviews Nature's Services: Societal Dependence on Natural Ecosystems edited by Gretchen C. Daily and The Work of Nature: How the Diversity of Life Sustains Us by Yvonne Baskin


Life in the freezer p529


Science in the service of the Raj p530

Ehsan Masood reviews The Science of Empire: Scientific Knowledge, Civilization, and Colonial Rule in India by Zaheer Baber and Mapping an Empire: The Geographical Construction of British India, 1765-1843 by Matthew H. Edney


A private function p532

Alison Jolly reviews Why is Sex Fun? The Evolution of Human Sexuality by Jared Diamond


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Articles

The role of nitrogen fixation in biogeochemical cycling in the subtropical North Pacific Ocean p533

D. Karl, R. Letelier, L. Tupas, J. Dore, J. Christian and D. Hebel


The complete genome sequence of the gastric pathogen Helicobacter pylori p539

Jean-F. Tomb, Owen White, Anthony R. Kerlavage, Rebecca A. Clayton, Granger G. Sutton, Robert D. Fleischmann, Karen A. Ketchum, Hans Peter Klenk, Steven Gill, Brian A. Dougherty, Karen Nelson, John Quackenbush, Lixin Zhou, Ewen F. Kirkness, Scott Peterson, Brendan Loftus, Delwood Richardson, Robert Dodson, Hanif G. Khalak, Anna Glodek, Keith McKenney, Lisa M. Fitzegerald, Norman Lee, Mark D. Adams, Erin K. Hickey, Douglas E. Berg, Jeanine D. Gocayne, Teresa R. Utterback, Jeremy D. Peterson, Jenny M. Kelley, Matthew D. Cotton, Janice M. Weidman, Claire Fujii, Cheryl Bowman, Larry Watthey, Erik Wallin, William S. Hayes, Mark Borodovsky, Peter D. Karp, Hamilton O. Smith, Claire M. Fraser and J. Craig Venter


A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB p548

Joseph A. DiDonato, Makio Hayakawa, David M. Rothwarf, Ebrahim Zandi and Michael Karin


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Letters to Nature

A rotating disk of gas and dust around a young counterpart to beta Pictoris p555

Vincent Mannings, David W. Koerner and Anneila I. Sargent


Observation of an internal wave attractor in a confined, stably stratified fluid p557

Leo R. M. Maas, Dominique Benielli, Joël Sommeria and Frans-Peter A. Lam


Discovery of a reactive azeotrope p561

W. Song, R. S. Huss, M. F. Doherty and M. F. Malone


Decadal predictability of North Atlantic sea surface temperature and climate p563

R. T. Sutton and M. R. Allen


Orbitally paced climate oscillations across the Oligocene/Miocene boundary p567

James C. Zachos, Benjamin P. Flower and Hilary Paul


Geodynamic estimates of the viscosity of the Earth's inner core p571

Bruce A. Buffett


Deep marine biosphere fuelled by increasing organic matter availability during burial and heating p573

Peter Wellsbury, Kim Goodman, Tanja Barth, Barry A. Cragg, Stephen P. Barnes and R. John Parkes


The fate of carbon in grasslands under carbon dioxide enrichment p576

Bruce A. Hungate, Elisabeth A. Holland, Robert B. Jackson, F. Stuart Chapin, III, Harold A. Mooney and Christopher B. Field


Net transfer of carbon between ectomycorrhizal tree species in the field p579

Suzanne W. Simard, David A. Perry, Melanie D. Jones, David D. Myrold, Daniel M. Durall and Randy Molina


Dissociating prefrontal and hippocampal function in episodic memory encoding p582

R. J. Dolan and P. C. Fletcher


Absence of opiate rewarding effects in mice lacking dopamine D2 receptors p586

Rafael Maldonado, Adolfo Saiardi, Olga Valverde, Tarek A. Samad, Bernard P. Roques and Emiliana Borrelli


Rab3A is essential for mossy fibre long-term potentiation in the hippocampus p590

Pablo E. Castillo, Roger Janz, Thomas C. Sdhof, Thanos Tzounopoulos, Robert C. Malenka and Roger A. Nicoll


Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion p593

Yun Wang, Masaya Okamoto, Frank Schmitz, Kay Hofmann and Thomas C. Südhof


Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II p598

Patrick D. Varga-Weisz, Matthias Wilm, Edgar Bonte, Katia Dumas, Matthias Mann and Peter B. Becker


Modelling teleconnections between the North Atlantic and North Pacific during the Younger Dryas p602

Uwe Mikolajewicz, Thomas J. Crowley, Andreas Schiller and Reinhard Voss


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New on the Market

The breakdown on bioinformatics p603

Hardware and software make up this survey — items include software for genomics work, DNA and protein sequence analysis, protein viewing, and a number of products for drug discovery and drug screening applications.

compiled by Brendan Horton from information provided by the manufacturers.


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