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Nature 388, 519-521 (7 August 1997) |
Signal transduction: I
B kinase all zipped up
Alain Israë1
NF-
B is a transcription factor that plays a central role in the immune and inflammatory response, and is also involved in controlling the expression of human immunodeficiency virus. A few years after this factor was identified1, it became clear that its activity is controlled by a previously unknown mechanism.
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