Table of contents


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Opinion

Progress on patents, but more action is needed p309

Europe's proposed directive on biotechnology patenting has passed its most difficult hurdle. But patent policy still faces problems, such as the way some claims are implemented, and the lack of a 'grace period'.


Planting a sound idea p309

The US Senate should be applauded for rejecting the administration's caution on plant genome sequencing.


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News

Pressure grows for inquiry into welfare of transgenic animals p311

Ehsan Masood


CNRS gets first woman director general p311

Declan Butler


NSF urged to increase plant genome sequencing effort p312

Colin Macilwain


Call for human subjects monitoring body p313

Sally Lehrman


Collins' student sanctioned over 'most severe' case of fraud p313

Rex Dalton


Euro-vote lifts block on biotech patents p314

Alison Abbott


...but parliament wants closer scrutiny p314

Alison Abbott


Swiss researchers facing 'anti-transgenics' vote p315

Quirin Schiermeier


Russian minister tells academy: streamlining must continue p315

Carl Levitin


Tokyo officials are told to agree on carbon strategy p316

Richard Nathan


Australia to rejoin space race with satellite project p316

Peter Pockley


NIH and genome project set for more funds p316

Colin Macilwain


Talks start on policing bio-weapons ban... p317

Declan Butler


...as 'designer weapons' threat is disputed p317

Declan Butler


News in Brief p318


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Correspondence

The serious business of listing authors p320

Christopher Stubbs


Cloning, dignity and ethical revisionism p320

Axel Kahn


Salmonella or Smithella? p320

Friedrich Katscher


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Commentary

Fat rats and carcinogenesis screening p321

It is poor science to use inappropriate strains of rodents in badly designed and inefficient experiments for testing the safety of chemicals. It is also costly and unethical because greater numbers of laboratory animals are needed.


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News and Views

Seeking wisdom in innate immunity p323

Douglas T. Fearon


Solar physics:  Gravity waves with a new spin p324

Douglas Gough


Palaeoanthropology:  Fossil muzzles and other puzzles p327

Meike Köhler and Salvador Moyà-Solà


River management:  What's best on the banks? p328

David R. Montgomery


Protein folding:  The difference with prokaryotes p329

Mary-Jane Gething


Extraterrestrial impacts:  Earth rocked by combination punch p331

Dieter Stöffler and Philippe Claeys


100 and 50 years ago p331


Homogeneous catalysis:  On the trail of dioxygen activation p332

Craig L. Hill and Ira A. Weinstock


An artist of the floating world p333

Kate McGeown


Daedalus:  A personal thermostat p333

David Jones


Obituary:  Jacques-Yves Cousteau (1910-97) p334

Roger Cans


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Scientific Correspondence

Recent subsidence of the northern Suez canal p335

Daniel J. Stanley and Glenn A. Goodfriend


Clouds without supersaturation p336

Markku Kulmala, Ari Laaksonen, Robert J.Charlson and Pekka Korhonen


A new west African chimpanzee subspecies? p337

M. Katherine Gonder, John F. Oates, Todd R. Disotell, Michael R. J. Forstner, Juan Carlos Morales and Don J. Melnick


Imaging individual green fluorescent proteins p338

Daniel W. Pierce, Nora Hom-Booher and Ronald D. Vale


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Book Reviews

On the trail of the transistor p339

Frederick Seitz reviews Crystal Fire: The Birth of the Information Age by Michael Riordan and Lillian Hoddeson


The magic of mushrooms p340


Ceaseless fluctuations p340

Ian Aitchison reviews Conceptual Developments of Twentieth Century Field Theories by Tian Yu Cao


In retrospect chosen by John L. Casti p341

John L. Casti reviews Gödel, Escher, Bach: An Eternal Golden Braid by Douglas Hofstadter


Correction p341

Stuart Sutherland reviews Psychology Astray: Fallacies in Studies of 'Repressed Memory' and Childhood Trauma by Harrison G. Pope, Jr


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Article

Recombination of protein domains facilitated by co-translational folding in eukaryotes p343

William J. Netzer and F. Ulrich Hartl


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Letters to Nature

A magnetic switch that determines the speed of astrophysical jets p350

D. L. Meier, S. Edgington, P. Godon, D. G. Payne and K. R. Lind


A ruthenium-substituted polyoxometalate as an inorganic dioxygenase for activation of molecular oxygen p353

Ronny Neumann and Mazal Dahan


On/off blinking and switching behaviour of single molecules of green fluorescent protein p355

Robert M. Dickson, Andrew B. Cubitt, Roger Y. Tsien and W. E. Moerner


The soil production function and landscape equilibrium p358

Arjun M. Heimsath, William E. Dietrich, Kunihiko Nishiizumi and Robert C. Finkel


Experimental and theoretical identification of a new high-pressure phase of silica p362

L. S. Dubrovinsky, S. K. Saxena, P. Lazor, R. Ahuja, O. Eriksson, J. M. Wills and B. Johansson


The age of the Popigai impact event and its relation to events at the Eocene/Oligocene boundary p365

Richard Bottomley, Richard Grieve, Derek York and Victor Masaitis


Earliest known Old World monkey skull p368

Brenda R. Benefit and Monte L. McCrossin


Apparent competition structures ecological assemblages p371

M. B. Bonsall and M. P. Hassell


Genetic interaction between male mating strategy and sex ratio in a marine isopod p373

Stephen M. Shuster and Clay Sassaman


Different types of fear-conditioned behaviour mediated by separate nuclei within amygdala p377

Simon Killcross, Trevor W. Robbins and Barry J. Everitt


Infants listen for more phonetic detail in speech perception than in word-learning tasks p381

Christine L. Stager and Janet F. Werker


Laminar fine structure of frequency organization in auditory midbrain p383

Christoph E. Schreiner and Gerald Langner


Kinesin hydrolyses one ATP per 8-nm step p386

Mark J. Schnitzer and Steven M. Block


Coupling of kinesin steps to ATP hydrolysis p390

Wei Hua, Edgar C. Young, Margaret L. Fleming and Jeff Gelles


A human homologue of the Drosophila Toll protein signals activation of adaptive immunity p394

Ruslan Medzhitov, Paula Preston-Hurlburt and Charles A. Janeway, Jr


A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA p397

Hlne Tronchre, Jiwu Wang and Xiang-Dong Fu


Correction:  Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation p400

Ed Laufer, Randall Dahn, Olivia E. Orozco, Chang-Yeol Yeo, Jacqueline Pisenti, Domingos Henrique, Ursula K. Abbott, John F. Fallon and Cliff Tabin


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Techniques and Technology

Using GFP to study virus invasion and spread in plant tissues p401

Karl J. Oparka, Alison G. Roberts, Simon Santa Cruz, Petra Boevink, Denton A.M. Prior and Anna Smallcombe


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New on the Market

Microscopy and image analysis p403

With the objective of reviewing recent releases in the field of microscopy, this feature looks at a variety of optical and confocal microscopes, instruments for SPM, SEM, AMF and TEM, as well as accessories and software.

compiled by Brendan Horton from information provided by the manufacturers.


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