Table of contents


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Opinion

Cooperation can help get the message across p1

Those who study natural phenomena that pose risks to society need to work more closely with social scientists to ensure their science is put into practice. Such cooperation could also boost their funding prospects.


Coming down to earth p1

Last week's UN meeting in New York was a salutary lesson in the realities if environmental politics


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News

Molecular biologists in Asia and Pacific plan research network p3

David Swinbanks


Promising signs for NSF budget increase p3

Colin Macilwain


Quake panel admits prediction is 'difficult' p4

David Swinbanks


German law could boost prospects for organ transplants p4

Alison Abbott


US air pollution rules stir up a stink about research p5

Tony Reichhardt


President of UN summit 'sobered' by outcome p5

Colin Macilwain


Cloning for research 'should be allowed' p6

Meredith Wadman


European biotech industry plans ethics panel p6

Declan Butler


France puts big science under scrutiny p7

Declan Butler


Uncertainty over fate of Mir experiments p8

Tony Reichhardt


Australian science review defends diversity and overlaps p8

Peter Pockley


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News Analysis

Asian tiger claws its way up the ratings p9

Taiwan has ambitious plans to achieve international stature in science, and is investing accordingly. It is pursuing long-term national goals for technology development and to boost support for its best scientists.

Philip Campbell


News in Brief p11


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Correspondence

Even sociologists need science p13

Jonathan R. Ellis


More danger in doctrine than in genetics p13

Christopher Badcock


George Wald believed in Apocalypse now p13

Thomas H. Jukes


Alphabetical listing and citation rates p14

Mark Shevlin and Mark N. O. Davies


CJD transmission p14

F.-X. Meslin


Greek is the word p15

Andreas Arvanitogiannis


Don't leave dignity out of the cloning debate p15

Karim Labib


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Commentary

The reform of Russian science p16

Six years after the end of Communist rule in Russia, attempts to reform Russian science have produced a mixed scorecard. There have been some substantial achievements, but there is still need for further changes.


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News and Views

Predicting where we walk p19

Michael Batty


Membrane fusion:  Bridging the gap by AAA ATPases p20

Tony Rowe and William E. Balch


Chemistry:  Oddly ordinary seaborgium p21

Ron Lougheed


Visual neurobiology:  Colouring the cortex p23

Karl R. Gegenfurtner


Astrophysics:  Not-so-cosmic rays p24

Peter L. Biermann


Palaeoclimatology:  Back at the last interglacial p25

Joël Guiot


Environmental engineering p27

Tim Lincoln


100 and 50 years ago p28


Signal transduction:  Mad about SMADs p28

Jeff Wrans and Tony Pawson


Semiconductors:  Do the twist to get fit p29

Pauline Rigby


Daedalus:  The watch on the line p30

David Jones


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Scientific Correspondence

Inhibition of ICE slows ALS in mice p31

Robert M. Friedlander, Robert H. Brown, Valeria Gagliardini, Joy Wang and Junying Yuan


Electronic properties of carbon toroids p31

R. C. Haddon


Vision in dim light p32

David H. Hubel


A polymerase I palm in adenylyl cyclase? p33

Peter J. Artymiuk, Andrew R. Poirrette, David W. Rice and Peter Willett


Reply:  A polymerase I palm in adenylyl cyclase? p34

Stephen H. Bryant, Tom Madej, Joel Janin, Yu Liu, Arnold E. Ruoho, Gongyi Zhang and James H. Hurley


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Book Reviews

The health of a nation p35

W. F. Bynum


France's famous scientific immortal p35


New in paperback p36


The higher idiocy p36

Walter Gratzer


Riddles in the sky p37

Wendy Freedman


The lure of the red planet p37


Science and salvation p38

George Marsden


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Article

Evidence for human influence on climate from hemispheric temperature relations p39

Robert K. Kaufmann and David I. Stern


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Letters to Nature

Detection of ozone on Saturn's satellites Rhea and Dione p45

K. S. Noll, T. L. Roush, D. P. Cruikshank, R. E. Johnson and Y. J. Pendleton


Modelling the evolution of human trail systems p47

Dirk Helbing, Joachim Keltsch and Péter Molnár


Current switching of resistive states in magnetoresistive manganites p50

A. Asamitsu, Y. Tomioka, H. Kuwahara and Y. Tokura


Controlled production of aligned-nanotube bundles p52

M. Terrones, N. Grobert, J. Olivares, J. P. Zhang, H. Terrones, K. Kordatos, W. K. Hsu, J. P. Hare, P. D. Townsend, K. Prassides, A. K. Cheetham, H. W. Kroto and D. R. M. Walton


Chemical properties of element 106 (seaborgium) p55

M. Schädel, W. Brüchle, R. Dressler, B. Eichler, H. W. Gäggeler, R. Günther, K. E. Gregorich, D. C. Hoffman, S. Hübener, D. T. Jost, J. V. Kratz, W. Paulus, D. Schumann, S. Timokhin, N. Trautmann, A. Türler, G. Wirth and A. Yakuschev


Vegetation and climate change in northwest America during the past 125 kyr p57

Cathy Whitlock and Patrick J. Bartlein


Endemic African mammals shake the phylogenetic tree p61

Mark S. Springer, Gregory C. Cleven, Ole Madsen, Wilfried W. de Jong, Victor G. Waddell, Heather M. Amrine and Michael J. Stanhope


Hypothermia in foraging king penguins p64

Y. Handrich, R. M. Bevan, J.-B. Charrassin, P. J. Butler, K. Ptz, A. J. Woakes, J. Lage and Y. Le Maho


Colour tuning in human visual cortex measured with functional magnetic resonance imaging p68

Stephen Engel, Xuemei Zhang and Brian Wandell


Hippocampal GABAAchannel conductance increased by diazepam p71

M. Eghbali, J. P. Curmi, B. Birnir and P. W. Gage


p47 is a cofactor for p97-mediated membrane fusion p75

Hisao Kondo, Catherine Rabouille, Richard Newman, Timothy P. Levine, Darryl Pappin, Paul Freemont and Graham Warren


Cofilin promotes rapid actin filament turnover in vivo p78

Pekka Lappalainen and David G. Drubin


Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 p82

Akiko Hata, Roger S. Lo, David Wotton, Giorgio Lagna and Joan Massagué


A structural basis for mutational inactivation of the tumour suppressor Smad4 p87

Yigong Shi, Akiko Hata, Roger S. Lo, Joan Massagué and Nikola P. Pavletich


DNA-replication checkpoint control at the Drosophila midblastula transition p93

Ody C. M. Sibon, Victoria A. Stevenson and William E. Theurkauf


Structure of the multimodular endonuclease FokI bound to DNA p97

David A. Wah, Joel A. Hirsch, Lydia F. Dorner, Ira Schildkraut and Aneel K. Aggarwal


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New on the Market

Taking inventory of biological reagents p101

Whether you are combing the shelves or digging in the back of the freezer, that missing reagent might just be here, such as cell-cycle antibodies, peptide controls, CO and haem oxygenases and those elusive FISH probes.

compiled by Brendan Horton from information provided by the manufacturers.


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