| | Opinion |  |
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| | Time for a firm grasp on UK science priorities 743
The Labour party is expected to win the election in the United Kingdom next week, but it has so far provided little to inspire researchers. The challenges that face it are chronic and require management with insight.
doi:10.1038/386743a0
PDF (246K)
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| | Tip of an iceberg? 743
All of Japan's semi-government research and development needs critical re-examination.
doi:10.1038/386743b0
PDF (246K)
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| | News | |
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| | Austrian gene food petition puts pressure on European partners 745
Alison Abbott
doi:10.1038/386745a0
PDF (261K)
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| | US advisory panel backs ITER design 745
David Kramer
doi:10.1038/386745b0
PDF (262K)
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| | Scientists dispute wisdom of Canada reopening fishery 746
David Spurgeon
doi:10.1038/386746a0
PDF (272K)
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| | Accident fall-out threatens Japan's nuclear company 746
David Swinbanks
doi:10.1038/386746b0
PDF (272K)
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| | Baylor backed over 'falsified data' claims 747
Rex Dalton
doi:10.1038/386747a0
PDF (262K)
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| | Patent office replies to fears over ESTs 747
Meredith Wadman
doi:10.1038/386747b0
PDF (262K)
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| | LHC and space station get funding strings 748
Meredith Wadman
doi:10.1038/386748a0
PDF (261K)
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| | Creationist 'Ark' trial closes early after judge narrows focus 748
Peter Pockley
doi:10.1038/386748b0
PDF (261K)
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| | Labour keeps its supporters guessing 749
David Dickson
doi:10.1038/386749a0
PDF (427K)
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| | Return to Unesco beckons for Britain 749
DAVID DICKSON
doi:10.1038/386749b0
PDF (428K)
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| | Computer sanctions 'could affect US weapons research' 750
David Kramer
doi:10.1038/386750a0
PDF (267K)
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| | Human origins centre pulls up roots in move to Arizona 750
Sally Lehrman
doi:10.1038/386750b0
PDF (267K)
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| | India takes French route to genome project 750
K. S. Jayaraman
doi:10.1038/386750c0
PDF (267K)
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| | News Analysis | |
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| | Germany divided on a single academy 751
Germany is developing plans for a national academy of sciences, but the country's regional academies and a learned society have differing ideas.
Quirin Schiermeier
doi:10.1038/386751a0
PDF (264K)
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| | News in Brief | |
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| | News in brief 752
doi:10.1038/386752a0
PDF (265K)
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| | Correspondence | |
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| | No lack of individuality 754
P.-L. Chau & W. Y. Chau
doi:10.1038/386754a0
PDF (328K)
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| | Sequence is all there 754
Takashi Horiuchi
doi:10.1038/386754b0
PDF (328K)
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| | Contract researchers still out in the cold 754
Tina Yates
doi:10.1038/386754c0
PDF (328K)
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| | Value-added Frontiers programme 755
Tom Blundell
doi:10.1038/386755a0
PDF (264K)
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| | Ginkgo thrives 755
Wilhelm Schmid
doi:10.1038/386755b0
PDF (264K)
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| | Todd's achievement 755
Raphael Mechoulam
doi:10.1038/386755c0
PDF (264K)
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| | Commentary |  |
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| | A man for our season 757
Science is in a parlous state − passing fashions, a star system and the new cult of management have combined to strangle originality. The ethics of V. B. Wigglesworth offer a cure.
Peter A. Lawrence & Michael Locke
doi:10.1038/386757a0
PDF (672K)
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| | News and Views |  |
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| | The AM and FM of calcium signalling 759
Cells respond to external signals by transducing the information into internal messengers such as Ca2+. The information-processing capability of the Ca2+ signalling system is enhanced by the well-known engineering principles of amplitude and frequency modulation.
Michael J. Berridge
doi:10.1038/386759a0
PDF (797K)
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| | Magnetic energy release on the Sun 760
James A. Klimchuk
doi:10.1038/386760a0
PDF (667K)
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| | Gatekeepers and caretakers 761
Kenneth W. Kinzler & Bert Vogelstein
doi:10.1038/386761a0
PDF (613K)
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| | Lights turning red on amber 764
Bryan Sykes
doi:10.1038/386764a0
PDF (836K)
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| | Not from books but from dissections 764
Stephen Battersby
doi:10.1038/386764b0
PDF (413K)
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| | Sighting the seas of Europa 765
William B. McKinnon
doi:10.1038/386765a0
PDF (705K)
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| | Breaking the rule of three 767
Jean-Louis Mandel
doi:10.1038/386767a0
PDF (1,231K)
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| | 100 years ago 768
doi:10.1038/386768a0
PDF (676K)
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| | Towards a neuropathology of emotion and mood 769
Antonio R. Damasio
doi:10.1038/386769a0
PDF (819K)
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| | Thought versus feeling 770
David Jones
doi:10.1038/386770a0
PDF (541K)
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| | Scientific Correspondence | |
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| | A fungal minisatellite 771
Thomas H. Andersen & Torsten Nilsson-Tillgren
doi:10.1038/386771a0
PDF (373K)
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| | The one that got away 771
Thomas P. Russell & Sanat K. Kumar
doi:10.1038/386771b0
PDF (791K)
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| | Transcriptional activation functions in BRCA2 772
Jonathan Milner, Bruce Ponder, Luke Hughes-Davies, Matthias Seltmann & Tony Kouzarides
doi:10.1038/386772a0
PDF (840K)
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| | Infrared detection in a beetle 773
Helmut Schmitz, Horst Bleckmann & Manfred Mürtz
doi:10.1038/386773a0
PDF (853K)
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| | Pet cat hair implicates murder suspect 774
Marilyn A. Menotti-Raymond, Victor A. David & Stephen J. O'Brien
doi:10.1038/386774a0
PDF (416K)
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| | Book Reviews | |
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| | Ten ground squirrels dancing 775
Mark Pagel reviews The Kingdom Field Guide to African Mammals
by
Jonathan Kingdon
doi:10.1038/386775a0
PDF (332K)
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| | Does this man ever sleep? 776
Geoffrey K. Pullum reviews Noam Chomsky: A Life of Dissent
by
Robert F. Barsky
doi:10.1038/386776a0
PDF (302K)
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| | Funding fathers 776
Wolf-Hagen Krauth reviews Der Stifterverband für die Deutsche Wissenschaft 1920−1995
by
Winfried Schulze
doi:10.1038/386776b0
PDF (815K)
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| | Cultural cliffhanger 777
doi:10.1038/386777a0
PDF (517K)
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| | Soft cell 778
Jeremy Hyams reviews Life Itself
by
Boyce Rensberger
doi:10.1038/386778a0
PDF (498K)
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| | The little changeling 778
doi:10.1038/386778b0
PDF (498K)
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| | Review Article | |
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| | Nucleocytoplasmic transport: signals, mechanisms and regulation 779
Erich A. Nigg
doi:10.1038/386779a0
PDF (2,457K)
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| | Articles |  |
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| | Effect of orogeny, plate motion and land−sea distribution on Eurasian climate change over the past 30 million years 788
Gilles Ramstein, Frédéric Fluteau, Jean Besse & Sylvie Joussaume
doi:10.1038/386788a0
PDF (1,645K)
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| | Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene 796
Amin Fazeli, Stephanie L. Dickinson, Michelle L. Hermiston, Robert V. Tighe, Robert G. Steen, Clayton G. Small, Esther T. Stoeckli, Kazuko Keino-Masu, Masayuki Masu, Helen Rayburn, Jonathan Simons, Roderick T. Bronson, Jeffrey I. Gordon, Marc Tessier-Lavigne & Robert A. Weinberg
doi:10.1038/386796a0
PDF (3,612K)
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| | Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
804
Shyam K. Sharan, Masami Morimatsu, Urs Albrecht, Dae-Sik Lim, Eva Regel, Christopher Dinh, Arthur Sands, Gregor Eichele, Paul Hasty & Allan Bradley
doi:10.1038/386804a0
PDF (1,921K)
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| | Letters | |
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| | Bi-directional plasma jets produced by magnetic reconnection on the Sun 811
D. E. Innes, B. Inhester, W. I. Axford & K. Wilhelm
doi:10.1038/386811a0
PDF (932K)
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| | An X-ray-induced insulator−metal transition in a magnetoresistive manganite 813
V. Kiryukhin, D. Casa, J. P. Hill, B. Keimer, A. Vigliante, Y. Tomioka & Y. Tokura
doi:10.1038/386813a0
PDF (974K)
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| | Fingering in granular flows 816
O. Pouliquen, J. Delour & S. B. Savage
doi:10.1038/386816a0
PDF (778K)
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| | Rapid climate change in the North Atlantic during the Younger Dryas recorded by deep-sea corals 818
Jodie E. Smith, Michael J. Risk, Henry P. Schwarcz & Ted A. McConnaughey
doi:10.1038/386818a0
PDF (838K)
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| | Hydrothermal gold mineralization in the Witwatersrand basin 820
A. C. Barnicoat, I. H. C. Henderson, R. J. Knipe, B. W. D. Yardley, R. W. Napier, N. P. C. Fox, A. K. Kenyon, D. J. Muntingh, D. Strydom, K. S. Winkler, S. R. Lawrence & C. Cornford
doi:10.1038/386820a0
PDF (2,609K)
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| | Subgenual prefrontal cortex abnormalities in mood disorders 824
Wayne C. Drevets, Joseph L. Price, Joseph R. Simpson Jr, Richard D. Todd, Theodore Reich, Michael Vannier & Marcus E. Raichle
doi:10.1038/386824a0
PDF (1,023K)
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| | Relationship between subjective effects of cocaine and dopamine transporter occupancy 827
N. D. Volkow, G.-J. Wang, M. W. Fischman, R. W. Foltin, J. S. Fowler, N. N. Abumrad, S. Vitkun, J. Logan, S. J. Gatley, N. Pappas, R. Hitzemann & C. E. Shea
doi:10.1038/386827a0
PDF (978K)
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| | Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects 830
N. D. Volkow, G.-J. Wang, J. S. Fowler, J. Logan, S. J. Gatley, R. Hitzemann, A. D. Chen, S. L. Dewey & N. Pappas
doi:10.1038/386830a0
PDF (1,183K)
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| | Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors 833
E. David Leonardo, Lindsay Hinck, Masayuki Masu, Kazuko Keino-Masu, Susan L. Ackerman & Marc Tessier-Lavigne
doi:10.1038/386833a0
PDF (1,602K)
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| | The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein 838
Susan L. Ackerman, Leslie P. Kozak, Stefan A. Przyborski, Laurie A. Rund, Bert B. Boyer & Barbara B. Knowles
doi:10.1038/386838a0
PDF (1,991K)
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| | Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion 843
Marc G. Coppolino, Michael J. Woodside, Nicolas Demaurex, Sergio Grinstein, René St-Arnaud & Shoukat Dedhar
doi:10.1038/386843a0
PDF (1,077K)
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| | Dodecamer repeat expansion in cystatin B gene in progressive myoclonus epilepsy 847
Maria D. Lalioti, Hamish S. Scott, Catherine Buresi, Colette Rossier, Armand Bottani, Michael A. Morris, Alain Malafosse & Stylianos E. Antonarakis
doi:10.1038/386847a0
PDF (2,115K)
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| | An achaete-scute homologue essential for neuroendocrine differentiation in the lung 852
Michael Borges, R. Ilona Linnoila, Helgi J. K. van de Velde, Herbert Chen, Barry D. Nelkin, Mack Mabry, Stephen B. Baylin & Douglas W. Ball
doi:10.1038/386852a0
PDF (1,562K)
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| | Differential activation of transcription factors induced by Ca2+ response amplitude and duration 855
Ricardo E. Dolmetsch, Richard S. Lewis, Christopher C. Goodnow & James I. Healy
doi:10.1038/386855a0
PDF (1,928K)
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| | New on the Market | |
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| | Collected for separation 859
Chromatography selections for this issue include a system designed to increase the productivity of automated microbore analysis, a column for capillary electrochromatography and chromatography data system software.
Brendan Norton
doi:10.1038/386859a0
PDF (1,459K)
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