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Scientific Correspondence
Nature 379, 682 (22 February 1996) | doi:10.1038/379682a0
CD95 ligand in graft rejection
Hideo Yagita, Ken-ichiro Seino, Nobuhiko Kayagaki & Ko Okumura
SIR - Bellgrau et al.1 suggested that testi-cular allografts expressing functional CD95 ligand (CD95L) evade rejection by inducing apoptotic death of CD95-expressing recipient T cells activated in response to graft antigens. This implied that CD95L might be useful for creating immune-privileged tissue for a variety of transplant uses (see also ref.
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