| | Opinion |  |
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| | Valediction from an old hand 521
John Maddox steps down as editor of Nature from this issue, to be replaced by Dr Philip Campbell.
John Maddox
doi:10.1038/378521a0
PDF (691K)
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| | News | |
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| | Climate panel confirms human role in warming, fights off oil states 524
Ehsan Masood
doi:10.1038/378524a0
PDF (256K)
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| | Argentina may host cosmic ray detector 524
doi:10.1038/378524b0
PDF (256K)
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| | Scientists 'must assert their independence' 525
David Dickson
doi:10.1038/378525a0
PDF (304K)
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| | ClA's psychic spies under scrutiny 525
Sally Lehrman
doi:10.1038/378525b0
PDF (304K)
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| | Report on US nuclear repository 'needs effective peer review' 526
Colin Macilwain
doi:10.1038/378526a0
PDF (270K)
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| | Planetary defence mission to yield pay-off for research 526
Tony Reichhardt
doi:10.1038/378526b0
PDF (270K)
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| | Italian science gains budget boost, still awaits reform 527
Alison Abbott
doi:10.1038/378527a0
PDF (289K)
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| | Stardust mission will collect comet dust 527
doi:10.1038/378527b0
PDF (289K)
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| | Japan launches plans for Moon probe and new satellite vehicle 527
Stephen Barker
doi:10.1038/378527c0
PDF (289K)
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| | School standards stress scientific literacy 528
Colin Macilwain
doi:10.1038/378528a0
PDF (260K)
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| | School standards stress scientific literacy 528
Colin Macilwain
doi:10.1038/378528b0
PDF (260K)
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| | Genome research risks abuse, panel warns 529
doi:10.1038/378529a0
PDF (317K)
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| | Medical rivals consider joint operations 529
Sally Lehrman
doi:10.1038/378529b0
PDF (317K)
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| | Leipzig professor's death stirs bitter feeling 530
Alison Abbott
doi:10.1038/378530a0
PDF (291K)
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| | AIDS survey traces shifting attitudes 530
Catherine Tastemain
doi:10.1038/378530b0
PDF (291K)
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| | UK science budget avoids the spending axe 531
Ehsan Masood
doi:10.1038/378531a0
PDF (266K)
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| | Rabbit virus threatens ecology after leaping the fence 531
Mark Lawson
doi:10.1038/378531b0
PDF (266K)
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| | Correspondence | |
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| | Patents and indigenous lore 532
D. Balasubramanian
doi:10.1038/378532a0
PDF (439K)
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| | Patents and indigenous lore 532
Harrry Miller
doi:10.1038/378532b0
PDF (439K)
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| | Anticancer drugs 532
David M. Reese
doi:10.1038/378532c0
References | PDF (440K)
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| | Science in an occupied country 533
PÉteris Ozolin
doi:10.1038/378533a0
References | PDF (288K)
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| | Restoring good manners 533
Michael J. Morgan
doi:10.1038/378533b0
PDF (288K)
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| | Commentary |  |
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| | The case for genomic patenting 534
Opposition to the patenting of genomic inventions threatens to erode the foundation of intellectual property rights needed to convert innovative research into new drugs, vaccines and diagnostic tests.
George Posts
doi:10.1038/378534a0
References | PDF (836K)
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| | Science in China | |
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| | China still hopeful ten years on 537
China's science is in much better shape than a decade ago, but there is still a long way to go. A cumbersome language and the prospect of political instability are amongst the problems to be overcome
doi:10.1038/378537a0
PDF (6,732K)
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| | News and Views |  |
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| | Contention over growth promoters 553
Unwelcome technical findings can cause ructions when they are made public, for which reason the technical community has a responsibility to its findings to argue its case in advance with their opponents.
John Maddox
doi:10.1038/378553a0
PDF (280K)
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| | Power laws and universality 554
H.Eugene Stanley
doi:10.1038/378554a0
References | PDF (284K)
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| | A nice ring to the centrosome 555
Berl R. Oakley
doi:10.1038/378555a0
References | PDF (624K)
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| | Jeffries Wyman (1901-95) 556
John T. Edsall
doi:10.1038/378556a0
PDF (254K)
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| | Mapping to the point 557
Richard Korn & Yashin Ramkissoon
doi:10.1038/378557a0
References | PDF (658K)
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| | A driver of glaciation cycles? 558
Donald E. Brownlee
doi:10.1038/378558a0
References | PDF (278K)
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| | From out of the blue 559
George Sugihara
doi:10.1038/378559a0
References | PDF (615K)
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| | At the roots of nutrition 560
Julian I. Schroeder
doi:10.1038/378560a0
References | PDF (610K)
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| | An elusive soluble suppressor 561
Anthony S. Fauci
doi:10.1038/378561a0
References | PDF (279K)
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| | Probing times for Jupiter 562
Andrew P. Ingersoll
doi:10.1038/378562a0
References | PDF (286K)
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| | Reformed rubbish 562
David Jones
doi:10.1038/378562b0
PDF (286K)
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| | Scientific Correspondence | |
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| | HIV suppression by interleukin-16 563
Michael Baier, Albrecht Werner, Norbert Bannert, Karin Metzner & Reinhard Kurth
doi:10.1038/378563a0
References | PDF (472K)
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| | Tetrodotoxin as a pheromone 563
Kendo Matsumura
doi:10.1038/378563b0
References | PDF (810K)
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| | Ovalocytosis and cerebral malaria 564
Blaise Genton, Fadwa AI-Yaman, Charles S. Mgone, Neal Alexander, Michael M. Paniu, Michael P. Alpers & David Mokela
doi:10.1038/378564a0
References | PDF (576K)
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| | Extrapolation or attention shift? 565
Marcus Vinicius C. Baldo & Stanley A. Klein
doi:10.1038/378565a0
PDF (475K)
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| | Extrapolation or attention shift? 566
Beena Khurana & Romi Nijhawan
doi:10.1038/378566a0
References | PDF (254K)
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| | Book Reviews | |
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| | Chemistry imagined 567
Peter Atkins reviews Force of Nature: The Life of Linus Pauling
Thomas Hager and Linus Pauling: A Life in Science and Politics
By
Ted Goertzel & Ben Goertzel and Linus Pauling in His Own Words: Selections from His Writings, Speeches, and
Interviews
Edited by
B. Marinacci
doi:10.1038/378567a0
PDF (539K)
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| | Knowledge in the making 568
Edward J. Hackett reviews Places of Inquiry: Research and Advanced Education in Modern Universities
by
Burton R. Clark.
doi:10.1038/378568a0
PDF (618K)
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| | Deadly excuses 570
Kristle Macrakis reviews Death and Deliverance: Euthanasia in Germany, 1900-1945.
by
Michael Burleigh.
doi:10.1038/378570a0
PDF (277K)
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| | Review Article | |
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| | Making continental crust 571
Roberta L. Rudnick
doi:10.1038/378571a0
Abstract & References | PDF (2,227K)
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| | Articles |  |
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| | Nucleation of microtubule assembly by a  -tubulin-containing ring complex 578
Yixian Zheng, Mei Lie Wong, Bruce Alberts & Tim Mitchison
doi:10.1038/378578a0
Abstract & References | PDF (1,778K)
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| | Structure and ligand recognition of the phosphotyrosine binding domain of Shc 584
Ming-Ming Zhou, Kodimangalam S. Ravichandran, Edward T. Olejniczak, Andrew M. Petros, Robert P. Meadows, Michael Sattler, John E. Harlan, Warren S. Wade, Steven J. Burakoff & Stephen W. Fesik
doi:10.1038/378584a0
Abstract & References | PDF (2,923K)
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| | Letters | |
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| | Generation of lightning in Jupiter's water cloud 592
S. Gibbard, E. H. Levy & J. I. Lunine
doi:10.1038/378592a0
First paragraph & References | PDF (825K)
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| | Evidence from molecular dynamics simulations for non-metallic behaviour of solid hydrogen above 160 GPa 595
John S. Tse & Dennis D. Klug
doi:10.1038/378595a0
First paragraph & References | PDF (650K)
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| | Experimental confirmation of universality for a phase transition in two dimensions 597
C. H. Back, Ch. Würsch, A. Vaterlaus, U. Ramsperger, U. Maier & D. Pescia
doi:10.1038/378597a0
First paragraph & References | PDF (966K)
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| | A 100-kyr periodicity in the flux of extraterrestrial 3He to the sea floor
600
K. A. Parley & D. B. Patterson
doi:10.1038/378600a0
First paragraph & References | PDF (924K)
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| | Atmospheric carbon dioxide concentrations before 2.2 billion years ago 603
Rob Rye, Phillip H. Kuo & Heinrich D. Holland
doi:10.1038/378603a0
First paragraph & References | PDF (674K)
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| | An exceptionally widespread ignimbrite with implications for pyroclastic flow emplacement 605
C. J. N. Wilson, B. F. Houghton, P. J. J. Kampt & M. O. McWilliamst
doi:10.1038/378605a0
First paragraph & References | PDF (702K)
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| | Possible flush instability in mantle convection at the Archaean−Proterozoic transition 608
D. Breuer & T. Spohn
doi:10.1038/378608a0
First paragraph & References | PDF (938K)
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| | Unexpected dominance of high frequencies in chaotic nonlinear population models 610
Joel E. Cohen
doi:10.1038/378610a0
First paragraph & References | PDF (586K)
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| | Visually evoked calcium action potentials in cat striate cortex 612
Judith A. Hirsch, José-Manuel Alonso & R. Clay Reid
doi:10.1038/378612a0
First paragraph & References | PDF (896K)
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| | Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand 617
Iqbal S. Grewal, Jianchao Xu & Richard A. Flavell
doi:10.1038/378617a0
First paragraph & References | PDF (693K)
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| | CD40 ligand-transduced co-stimulation of T cells in the development of helper function 620
Dominic van Essen, Hitoshi Kikutani & David Gray
doi:10.1038/378620a0
First paragraph & References | PDF (1,143K)
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| | Functional impact of syntaxin on gating of N-type and Q-type calcium channels 623
I. Bezprozvanny, R.H. Scheller & R.W. Tsien
doi:10.1038/378623a0
First paragraph & References | PDF (884K)
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| | A phosphate transporter from the mycorrhizal fungus Glomus versiforme
626
Maria J. Harrison & Marianne L. van Buuren
doi:10.1038/378626a0
First paragraph & References | PDF (1,040K)
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| | A channel-like transporter for NH4
+ on the symbiotic interface of N2-fixing plants 629
Stephen D. Tyerman, Lynne F. Whitehead & David A. Day
doi:10.1038/378629a0
First paragraph & References | PDF (842K)
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| | Role of auxilin in uncoating clathrin-coated vesicles 632
Ernst Ungewickell, Huberta Ungewickell, Susanne E.H. Holstein, Robert Lindner, Kondury Prasad, Winifred Barouch, Brian Martini, Lois E. Greene & Evan Eisenberg
doi:10.1038/378632a0
First paragraph & References | PDF (1,062K)
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| | Actin-based motility of vaccinia virus 636
Sally Cudmore, Pascale Cossart, Gareth Griffiths & Michael Way
doi:10.1038/378636a0
First paragraph & References | PDF (908K)
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| | Microtubule nucleation by -tubulin-containing rings in the centrosome 638
Michelle Moritz, Michael B. Braunfeld, John W. Sedat, Bruce Alberts & David A. Agard
doi:10.1038/378638a0
First paragraph & References | PDF (1,169K)
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| | Crystal structures of human calcineurin and the human FKBP12−FK506−calcineurin complex 641
Charles R. Kissinger, Hans E. Parge, Daniel R. Knighton, Cristina T. Lewis, Laura A. Pelletier, Anna Tempczyk, Vincent J. Kalish, Kathleen D. Tucker, Richard E. Showalter, Ellen W. Moomaw, Louis N. Gastinel, Noriyuki Habuka, Xinghai Chen, Fausto Maldonado, John E. Barker, Russell Bacquet & J. Ernest Villafranca
doi:10.1038/378641a0
First paragraph & References | PDF (1,057K)
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| | Errata | |
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| | A protein catalytic framework with an N-terminal nucleophile is capable of self-activation 644
James A. Brannigan, Guy Dodson, Helen J. Duggleby, Peter C.E. Moody, Janet L. Smith, Diana R. Tomchick & Alexey G. Murzin
doi:10.1038/378644a0
PDF (233K)
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| | Predation risk and the cost of being fat 644
Andrew G. Cosier, Jeremy J. D. Greenwood & Christopher Perrins
doi:10.1038/378644b0
PDF (233K)
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| | Control of p70 S6 kinase by kinase activity of FRAP in vivo
644
Eric J. Brown, Peter A. Beal, Curtis T. Keith, Jie Chen, Tae Bum Shin & Stuart L. Schreiber
doi:10.1038/378644c0
PDF (233K)
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| | Product Reviews | |
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| | Non-invasive ion probes — tools for measuring transmembrane ion flux 645
lonophores, used in non-invasive vibrating electrodes, can directly monitor steady-state ion flux from single cells, even when the source is non-electrogenic.
Peter J. S. Smith
doi:10.1038/378645a0
References | PDF (1,351K)
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| | Cell studies 647
New research tools for the cell biologist include a fermenter, serum-free medium for insect cell lines, inverted research microscopes, and intracellular ion measurement and digital video microscopy systems.
Brendan Horton
doi:10.1038/378647a0
PDF (933K)
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