| | Opinion |  |
 |
| | Another anniversary to celebrate 1
Nature's pride in its survival this far should not be mistaken for evidence that the future can prudently be an extrapolation of the past. There are challenges and opportunities ahead.
doi:10.1038/372001a0
PDF (274K)
|
|
| | All change in Brussels 2
The European Commission in the New Year will influence European science, but nobody can yet tell how.
doi:10.1038/372002a0
PDF (130K)
|
|
| | News | |
|
| | NIH drops survey on discrimination, claiming questions 'ill-designed' 3
Colin Macilwain
doi:10.1038/372003a0
PDF (122K)
|
|
| | Tsunami experts left high and dry 3
David Swinbanks
doi:10.1038/372003b0
PDF (123K)
|
|
| | Germany debates future of research centres 4
Alison Abbott
doi:10.1038/372004a0
PDF (295K)
|
|
| | UK labs to stay in public ownership 4
David Dickson
doi:10.1038/372004b0
PDF (295K)
|
|
| | Frank Press to head new inquiry into US science policy 5
Colin Macilwain
doi:10.1038/372005a0
PDF (136K)
|
|
| | US to use science links to meet foreign policy goals 5
Colin Macilwain
doi:10.1038/372005b0
PDF (136K)
|
|
| | Scientists support expelled researcher 5
Declan Butler
doi:10.1038/372005c0
PDF (136K)
|
|
| | Institute to boost Japan sequencing efforts 6
David Swinbanks
doi:10.1038/372006a0
PDF (177K)
|
|
| | Euro-lobby backs animal research 6
Toni Feder
doi:10.1038/372006b0
PDF (177K)
|
|
| | Britain backs off compulsory year prior to PhD work 7
Maggie Verrall
doi:10.1038/372007a0
PDF (136K)
|
|
| | New EC appointees 'will seek to bind research to industry' 7
Declan Butler
doi:10.1038/372007b0
PDF (136K)
|
|
| | Meeting celebrates 125th birthday 7
doi:10.1038/372007c0
PDF (136K)
|
|
| | Republican gains could mean tighter budgets for science 8
Tony Reichhardt
doi:10.1038/372008a0
PDF (144K)
|
|
| | US to fund project to develop desk-top DNA screening tool 8
Sally Lehrmann
doi:10.1038/372008b0
PDF (144K)
|
|
| | Compromise sought over germplasm access 9
Daniel Putterman
doi:10.1038/372009a0
PDF (129K)
|
|
| | Road cuts urged to combat warming 9
Maggie Verrall
doi:10.1038/372009b0
PDF (129K)
|
|
| | Correspondence | |
|
| | Ownership and human genome 10
Alan R. Williamson & Keith O. EIIiston
doi:10.1038/372010a0
PDF (139K)
|
|
| | Drug testing 10
L. Uzych
doi:10.1038/372010b0
References | PDF (139K)
|
|
| | FRONTIERS OF IGNORANCE | |
|
| | How to mark 125 years of discovery 11
doi:10.1038/372011a0
PDF (301K)
|
|
| | The endless frontier 12
doi:10.1038/372012a0
PDF (271K)
|
|
| | Questions yet unanswered 13
doi:10.1038/372013a0
PDF (343K)
|
|
| | NATURE 14
doi:10.1038/372014a0
PDF (207K)
|
|
| | COSMOLOGY — FRONTIERS OF IGNORANCE | |
|
| | The best cosmology there is 15
doi:10.1038/372015a0
PDF (311K)
|
|
| | FRONTIERS OF IGNORANCE — COSMOLOGY | |
|
| | Holes in the Big Bang 16
doi:10.1038/372016a0
References | PDF (281K)
|
|
| | COSMOLOGY — FRONTIERS OF IGNORANCE | |
|
| | What the ancients believed 17
doi:10.1038/372017a0
References | PDF (543K)
|
|
| | MATTER — FRONTIERS OF IGNORANCE | |
|
| | One discovery inside another 19
doi:10.1038/372019a0
References | PDF (392K)
|
|
| | FRONTIERS OF IGNORANCE — MATTER | |
|
| | Building-blocks of matter 20
doi:10.1038/372020a0
PDF (116K)
|
|
| | MATTER — FRONTIERS OF IGNORANCE | |
|
| | The ghosts in the machine? 20
doi:10.1038/372020b0
References | PDF (330K)
|
|
| | The left-handed Universe 21
doi:10.1038/372021a0
PDF (330K)
|
|
| | FRONTIERS OF IGNORANCE — MATTER | |
|
| | The glue within the nucleus 22
doi:10.1038/372022a0
PDF (480K)
|
|
| | MATTER — FRONTIERS OF IGNORANCE | |
|
| | Vital yardstick hidden still 23
doi:10.1038/372023a0
PDF (365K)
|
|
| | Putting four forces together 23
doi:10.1038/372023b0
PDF (475K)
|
|
| | FRONTIERS OF IGNORANCE — MATTER | |
|
| | Bad press, bad luck 24
doi:10.1038/372024a0
PDF (112K)
|
|
| | OBJECTS IN THE GALAXY — FRONTIERS OF IGNORANCE | |
|
| | Stars, planets and the Earth 25
doi:10.1038/372025a0
PDF (310K)
|
|
| | FRONTIERS OF IGNORANCE — OBJECTS IN THE GALAXY | |
|
| | Laboratories for the future? 26
doi:10.1038/372026a0
PDF (282K)
|
|
| | OBJECTS IN THE GALAXY — FRONTIERS OF IGNORANCE | |
|
| | The technical dimension 27
doi:10.1038/372027a0
PDF (382K)
|
|
| | FRONTIERS OF IGNORANCE — OBJECTS IN THE GALAXY | |
|
| | How did the Earth form? 28
doi:10.1038/372028a0
PDF (161K)
|
|
| | HOW DID LIFE BEGIN — FRONTIERS OF IGNORANCE | |
|
| | Which is the chicken, and which the egg? 29
doi:10.1038/372029a0
PDF (161K)
|
|
| | RNA in primaeval genetics 29
doi:10.1038/372029b0
References | PDF (294K)
|
|
| | FRONTIERS OF IGNORANCE — HOW DID LIFE BEGIN | |
|
| | Guesswork and randomness (for now at least) 30
doi:10.1038/372030a0
References | PDF (132K)
|
|
| | EVOLUTION OF PEOPLE — FRONTIERS OF IGNORANCE | |
|
| | The age of australopithecines 31
doi:10.1038/372031a0
References | PDF (406K)
|
|
| | FRONTIERS OF IGNORANCE — HOW DID LIFE BEGIN | |
|
| | Our ancestors' ancestors 32
doi:10.1038/372032a0
References | PDF (224K)
|
|
| | HOW DID LIFE BEGIN — FRONTIERS OF IGNORANCE | |
|
| | Migration out of Africa 32
doi:10.1038/372032b0
PDF (224K)
|
|
| | BIOLOGY — FRONTIERS OF IGNORANCE | |
|
| | Gaps in molecular biology 33
doi:10.1038/372033a0
PDF (131K)
|
|
| | The mechanics of life 33
doi:10.1038/372033b0
PDF (275K)
|
|
| | FRONTIERS OF IGNORANCE — BIOLOGY | |
|
| | The great leap forward 34
doi:10.1038/372034a0
PDF (273K)
|
|
| | BIOLOGY — FRONTIERS OF IGNORANCE | |
|
| | Is the brain a computer? 35
doi:10.1038/372035a0
PDF (564K)
|
|
| | FRONTIERS OF IGNORANCE — BIOLOGY | |
|
| | Promise of biodiversity 36
doi:10.1038/372036a0
PDF (307K)
|
|
| | Energy source for cells 36
doi:10.1038/372036b0
PDF (308K)
|
|
| | Molecules in embryology 36
doi:10.1038/372036c0
PDF (308K)
|
|
| | News and Views |  |
|
| | In praise of the scientist as writer 37
Prizes of �500 are awarded to Dr Paul Grant and Dr Dan Hultmark, each of whom has provided Nature with an outstanding News and Views article during its 125th anniversary year.
Tim Lincoln
doi:10.1038/372037a0
PDF (130K)
|
|
| | Unveiling a new galaxy 38
David Burstein
doi:10.1038/372038a0
References | PDF (172K)
|
|
| | Hammerhead nailed down 39
Thomas R. Cech & Olke C. Uhlenbeck
doi:10.1038/372039a0
References | PDF (304K)
|
|
| | Conveying past climates 41
Ed Boyle & Andrew Weaver
doi:10.1038/372041a0
References | PDF (578K)
|
|
| | The economics of extinction 42
Robert M. May
doi:10.1038/372042a0
References | PDF (325K)
|
|
| | Overturning mantle models 43
William M. White
doi:10.1038/372043a0
References | PDF (451K)
|
|
| | Death in the thymus 44
Ken Shortman & Roland Scotlay
doi:10.1038/372044a0
References | PDF (281K)
|
|
| | Risky apolipoprotein in brain 45
Michel Goedert, Warren J. Strittmatter & Alien D. Roses
doi:10.1038/372045a0
References | PDF (283K)
|
|
| | Real recycling 46
David Jones
doi:10.1038/372046a0
PDF (135K)
|
|
| | Scientific Correspondence | |
|
| | Hotspots of benthic production 47
Eric W. Vetter
doi:10.1038/372047a0
References | PDF (158K)
|
|
| | Spatiotemporal chaos 48
Tomas Bohr & Eric Bosch Willem van de Water
doi:10.1038/372048a0
References | PDF (115K)
|
|
| | Standard weights in ancient Andes 49
Stephen M. Epstein
doi:10.1038/372049a0
References | PDF (139K)
|
|
| | The 'St Jude' gambit 49
Ian Dunn
doi:10.1038/372049b0
PDF (139K)
|
|
| | Renal endothelin and hypertension 50
Aaron Hoffman, Ehud Grossman, Zaid A. Abassi & Harry R. Keiser
doi:10.1038/372050a0
References | PDF (119K)
|
|
| | Renal endothelin and hypertension 50
Koji Maemura, Yukiko Kurihara, Hiroyuki Morita, Hiroki Kurihara & Yoshio Yazaki
doi:10.1038/372050b0
References | PDF (119K)
|
|
| | Book Reviews |  |
|
| | The rise and fall of science 51
A. Rupert Hall reviews The Scientific Revolution
By
H Floris Cohen
doi:10.1038/372051a0
PDF (419K)
|
|
| | Dispensing a dose of common sense 52
Alison Abbott reviews Forbidden Drugs: Understanding Drugs and Why People Take Them
By
Philip Robson
doi:10.1038/372052a0
PDF (327K)
|
|
| | Thinking on one's feet 53
Annette Karmiloff-Smith & Mark H. Johnson reviews A Dynamic Systems Approach to the Development of Cognition and Action
By
Esther
Thelen & Linda B. Smith
doi:10.1038/372053a0
PDF (262K)
|
|
| | A PENCHANT for penguins 53
doi:10.1038/372053b0
PDF (142K)
|
|
| | Being clever and knowing it 54
Marian Stamp Dawkins reviews The Animal Mind
By
James L. Gould & Carol Grant Gould
doi:10.1038/372054a0
PDF (123K)
|
|
| | Review Article | |
|
| | Mechanisms of intracellular protein transport 55
James E. Rothman
doi:10.1038/372055a0
Abstract & References | PDF (1,299K)
|
|
| | Articles |  |
|
| | Mantle plumes and episodic crustal growth 63
M. Stein & A. W. Hofmann
doi:10.1038/372063a0
Abstract & References | PDF (729K)
|
|
| | Three-dimensional structure of a hammerhead ribozyme 68
Heinz W. Pley, Kevin M. Flaherty & David B. McKay
doi:10.1038/372068a0
Abstract & References | PDF (895K)
|
|
| | Letters | |
|
| | The large-scale distribution of X-ray clusters of galaxies 75
A. K. Romer, C. A. Collins, H. Böhringer, R. G. Cruddace, H. Ebeling, H. T. MacGillivray & W. Voges
doi:10.1038/372075a0
First paragraph & References | PDF (330K)
|
|
| | Discovery of a nearby spiral galaxy behind the Milky Way 77
R. C. Kraan-Korteweg, A. J. Loan, W. B. Burton, O. Lahav, H. C. Ferguson, P. A. Henning & D. Lynden-Bell
doi:10.1038/372077a0
First paragraph & References | PDF (380K)
|
|
| | Photothermal spectroscopy with femtojoule sensitivity using a micromechanical device 79
J. R. Barnes, R. J. Stephenson, M. E. Welland, Ch. Gerber & J. K. Gimzewski
doi:10.1038/372079a0
First paragraph & References | PDF (332K)
|
|
| | Rapid climate transitions in a coupled ocean–atmosphere model 82
Stefan Rahmstorf
doi:10.1038/372082a0
First paragraph & References | PDF (515K)
|
|
| | Experimental simulations of explosive degassing of magma 85
H. M. Mader, Y. Zhang, J. C. Phillips, R. S. J. Sparks, B. Sturtevant & E. Stolper
doi:10.1038/372085a0
First paragraph & References | PDF (477K)
|
|
| | Optimal harvesting, economic discounting and extinction risk in fluctuating populations 88
Russell Lande, Steinar Engen & Bernt-Erik Saether
doi:10.1038/372088a0
First paragraph & References | PDF (356K)
|
|
| | Attentive novelty detection in humans is governed by pre-attentive sensory memory 90
H. Tiitinen, P. May, K. Reinikainen & R. Näätänen
doi:10.1038/372090a0
First paragraph & References | PDF (358K)
|
|
| | Amyloid-associated proteins  1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer  -protein into filaments 92
Jianyi Ma, Ann Yee, H. Bryan Brewer Jr, Saumya Das & Huntington Potter
doi:10.1038/372092a0
First paragraph & References | PDF (402K)
|
|
| | Pinopsin is a chicken pineal photoreceptive molecule 94
Toshiyuki Okano, Toru Yoshizawa & Yoshitaka Fukada
doi:10.1038/372094a0
First paragraph & References | PDF (442K)
|
|
| | Molecular determinants of voltage-dependent inactivation in calcium channels 97
Ji-Fang Zhang, Patrick T. Ellinor, Richard W. Aldrich & Richard W. Tsien
doi:10.1038/372097a0
First paragraph & References | PDF (418K)
|
|
| | T-cell apoptosis detected in situ during positive and negative selection in the thymus 100
Charles D. Surh & Jonathan Sprent
doi:10.1038/372100a0
First paragraph & References | PDF (671K)
|
|
| | New member of the winged-helix protein family disrupted in mouse and rat nude mutations 103
Michael Nehls, Dietmar Pfeifer, Michael Schorpp, Hans Hedrich & Thomas Boehm
doi:10.1038/372103a0
First paragraph & References | PDF (632K)
|
|
| | A new class of retinoids with selective inhibition of AP-1 inhibits proliferation 107
Andrea Fanjul, Marcia I. Dawson, Peter D. Hobbs, Ling Jong, James F. Cameron, Eli Harlev, Gerhart Graupner, Xian-Ping Lu & Magnus Pfahl
doi:10.1038/372107a0
First paragraph & References | PDF (440K)
|
|
| | Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix 111
Heinz W. Pley, Kevin M. Flaherty & David B. McKay
doi:10.1038/372111a0
First paragraph & References | PDF (270K)
|
|
| | Structural biology | |
|
| | First–line defence 114
Structural insight into the trimeric organization of the human mannose-binding protein sheds light on the workings of the non-clonal, innate immune response in vertebrates.
Guy Riddihough
doi:10.1038/372114a0
References | PDF (165K)
|
|
