| | Opinion |  |
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| | Where research creates prosperity 591
An international comparison of research spending by companies confirms the correlation between success and research spending and raises questions about the capacity of British companies to face the future.
doi:10.1038/369591a0
PDF (253K)
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| | News | |
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| | US puts large-scale AIDS vaccine trials on ice as 'premature' 593
Colin Macilwain
doi:10.1038/369593a0
PDF (190K)
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| | Mixed fortunes strike big spenders 593
doi:10.1038/369593b0
PDF (190K)
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| | NASA puts the squeeze on low-cost missions 594
Tony Reichhardt
doi:10.1038/369594a0
PDF (157K)
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| | Scientists urge peer review on historians 594
doi:10.1038/369594b0
PDF (157K)
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| | Germany names candidate site for ITER fusion reactor 595
Alison Abbott
doi:10.1038/369595a0
PDF (183K)
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| | France in bid to avoid deadlock over LHC decision 595
doi:10.1038/369595b0
PDF (183K)
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| | Fast reactor delays lead to Plutonium cutbacks in Japan 596
David Swinbanks
doi:10.1038/369596a0
PDF (147K)
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| | Computer networks break new ground in agency cooperation 596
David Swinbanks
doi:10.1038/369596b0
PDF (147K)
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| | Court orders DNA test over chemical claims 597
Sally Lehrman
doi:10.1038/369597a0
PDF (152K)
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| | Trials 'must compete for new funds' 597
Helen Gavaghan
doi:10.1038/369597b0
PDF (152K)
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| | Lords fail to reverse move to ban embryo treatment 598
Maggie Verrall
doi:10.1038/369598a0
PDF (136K)
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| | Double helix goes on public display 598
doi:10.1038/369598b0
PDF (136K)
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| | NCI restores funding to gene therapist seen as 'too
hasty' 598
Diane Gershon
doi:10.1038/369598c0
PDF (136K)
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| | French minister outlines research proposals 599
Declan Butler
doi:10.1038/369599a0
PDF (151K)
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| | Compromise reached on bioethics bill 599
doi:10.1038/369599b0
PDF (151K)
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| | East Europe 'needs sustainable universities' 600
Alison Abbott
doi:10.1038/369600a0
PDF (143K)
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| | Chemist to head Canadian science council 600
David Spurgeon
doi:10.1038/369600b0
PDF (143K)
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| | Correspondence | |
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| | European brain research 601
Jean-Pierre Changeux, P. Andersen, M. J. Berridge, C. Blakemore, T. Bliss, Alberto Ferrus Gamero, T. Freund, R. Grantyn, S. Grillner, K. Hepp, T. Hökfelt, J. Hounsgaard, H. Korn, R. Levi-Montalcini, R. Miles, J.-C. Schwartz, W. Singer, P. Strata, E.
S. Vizi, W. Wadman & S. Zeki
doi:10.1038/369601a0
PDF (141K)
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| | No hitch-hikers 601
Robert Brown
doi:10.1038/369601b0
PDF (141K)
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| | Many thanks 601
A. R. Kacimov
doi:10.1038/369601c0
PDF (141K)
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| | Commentary |  |
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| | If it ain't fixed, don't break it ... 602
Value-judgements about the need for more
'goal-directed' or 'basic' scientific
research beg the question of how the publicly funded scientific
enterprise works. An efficient management would start to put things
right.
Cecil H. Fox
doi:10.1038/369602a0
References | PDF (143K)
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| | News and Views |  |
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| | Can anyons be made more tractable? 603
Particles that are neither fermions nor bosons, but
something in between, appear to exist only fitfully, in special
circumstances, but may now have been made more easily
calculable.
John Maddox
doi:10.1038/369603a0
PDF (153K)
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| | Cycling splicing factors 604
David L. Spector
doi:10.1038/369604a0
References | PDF (153K)
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| | Memories are made of this? 605
Polly Matzinger
doi:10.1038/369605a0
References | PDF (298K)
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| | Stirring times for Mars 606
Sean C. Solomon
doi:10.1038/369606a0
References | PDF (286K)
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| | Hubble looks at a stellar nursery 607
Leslie Sage
doi:10.1038/369607a0
PDF (140K)
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| | Pitcairn before the Bounty
608
Jared M. Diamond
doi:10.1038/369608a0
PDF (280K)
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| | Bleaching catalyst revealed 609
Alan E. Comyns
doi:10.1038/369609a0
References | PDF (157K)
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| | Well-timed words 610
doi:10.1038/369610a0
PDF (209K)
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| | Pack deaths 610
doi:10.1038/369610b0
PDF (209K)
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| | Orbital link 610
doi:10.1038/369610c0
PDF (209K)
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| | Footprints in the dust 610
Charles M. Telesco
doi:10.1038/369610d0
References | PDF (356K)
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| | The importance of being GTP 611
Henry R. Bourne
doi:10.1038/369611a0
References | PDF (304K)
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| | The long view 612
David Jones
doi:10.1038/369612a0
PDF (157K)
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| | Scientific Correspondence | |
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| | How to observe comet impact 613
Peter J. T. Leonard
doi:10.1038/369613a0
References | PDF (142K)
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| | Mercury in Brazil 613
David Cleary, Iain Thornton, Nigel Brown, George Kazantzis, Trevor Delves & Simon Worthington
doi:10.1038/369613b0
References | PDF (281K)
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| | DNA recognition and the code 614
Benno Müller-Hill & Peter Kolkhof
doi:10.1038/369614a0
References | PDF (158K)
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| | Steadying the rates 615
C. G. Langereis, A. A. M van Hoof & F. J. Hilgen
doi:10.1038/369615a0
References | PDF (135K)
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| | Sea-level rise 615
Wouter Greuell
doi:10.1038/369615b0
PDF (277K)
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| | Sea-level rise 616
D. L. Sahagian, D.
K. Jacobs & F.
W. Schwartz
doi:10.1038/369616a0
References | PDF (159K)
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| | Pore region of K+ channel RACTK1 616
M. J. Sutcliffe & P.
R. Stanfield
doi:10.1038/369616b0
References | PDF (162K)
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| | Book Reviews | |
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| | If this be magic. 617
A. Rupert Hall reviews Science and the Secrets of Nature: Books of Secrets
in Medieval and Early Modern Culture
By
W. Eamon
doi:10.1038/369617a0
PDF (160K)
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| | Tracks in time 618
Douglas Palmer reviews The Palaeobiology of Trace Fossils
by
Stephen K. Donovan
doi:10.1038/369618a0
PDF (144K)
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| | Cosmic integers 618
John Polkinghorne reviews Is There A Universe?
by
Stanley L. Jaki
doi:10.1038/369618b0
PDF (144K)
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| | Environmental stewardship 619
R. J. Berry reviews Caring for Creation: An Ecumenical Approach to the
Environmental Crisis
By
Max Oelschlaeger and The Earth, Humanity
and God
by
Colin
A. Russell
doi:10.1038/369619a0
PDF (316K)
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| | The man in the ice 619
doi:10.1038/369619b0
PDF (188K)
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| | Fuelling the engines of growth 620
Kristie Macrakis reviews Opting for Oil: The Political Economy of
Technological Change in the West German Chemical Industry,
1945−1961
by
Raymond
G. Stokes
doi:10.1038/369620a0
PDF (145K)
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| | Article |  |
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| | Structural determinants for activation of the  -subunit of
a heterotrimeric G protein 621
David G. Lambright, Joseph
P. Noel, Heidi
E. Hamm & Paul
B. Sigler
doi:10.1038/369621a0
Abstract & References | PDF (1,300K)
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| | Letters | |
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| | Dust depletion in the inner disk of  Pictoris as a
possible indicator of planets 628
P. O. Lagage & E. Pantin
doi:10.1038/369628a0
First paragraph & References | PDF (366K)
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| | High-power laser diodes based on InGaAsP alloys 631
Manijeh Razeghi
doi:10.1038/369631a0
First paragraph & References | PDF (351K)
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|
| | Density-driven liquid−liquid phase separation in the
system
AI2O3−Y2O3
633
S. Aasland & P.
F. McMillan
doi:10.1038/369633a0
First paragraph & References | PDF (498K)
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| | Efficient manganese catalysts for low-temperature
bleaching 637
Ronald Hage, Jan
E. Iburg, Judith Kerschner, Jean
H. Koek, Edwin L.
M. Lempers, Rudi
J. Martens, Uday
S. Racherla, Stephen
W. Russell, Ton Swarthoff, M.
Robert P. van Vliet, Johann
B. Warnaar, Lodewijk van
der Wolf & Bert Krijnen
doi:10.1038/369637a0
First paragraph & References | PDF (332K)
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| | Pollen in marine sediments as an indicator of oxidation of
organic matter 639
Richard G. Keil, Feng Sheng Hu, Elizabeth
C. Tsamakis & John
I. Hedges
doi:10.1038/369639a0
First paragraph & References | PDF (369K)
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|
| | Subduction of Asian lithospheric mantle beneath Tibet inferred
from models of continental collision 642
Sean D. Willett & Christopher Beaumont
doi:10.1038/369642a0
First paragraph & References | PDF (911K)
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|
| | Implications of early hominid labyrinthine morphology for
evolution of human bipedal locomotion 645
Fred Spoor, Bernard Wood & Frans Zonneveld
doi:10.1038/369645a0
First paragraph & References | PDF (433K)
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|
| | Cytotoxic T-cell memory without antigen 648
Lisa. L. Lau, Beth D. Jamieson, T. Somasundaram & Rafi Ahmed
doi:10.1038/369648a0
First paragraph & References | PDF (545K)
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|
| | Virus-specific CD8+ T-cell memory determined by
clonal burst size 652
Sam Hou, Lisa Hyland, Kevin
W. Ryan, Allen Portner & Peter
C. Doherty
doi:10.1038/369652a0
First paragraph & References | PDF (374K)
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|
| | Immunoglobulin synthesis and generalized autoimmunity in mice
congenitally deficient in (+) T cells 654
Li Wen, Scott
J. Roberts, Joanne
L. Viney, F.
Susan Wong, Caroline Mallick, R.
Craig Findly, Qingshuang Peng, Joseph
E. Craft, Michael
J. Owen & Adrian
C. Mayday
doi:10.1038/369654a0
First paragraph & References | PDF (564K)
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|
| | Severe sensory and sympathetic deficits in mice lacking
neurotrophin-3 658
Isabel Fariñas, Kevin
R. Jones, Carey Backus, Xiao-Yun Wang & Louis
F. Reichardt
doi:10.1038/369658a0
First paragraph & References | PDF (631K)
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|
| | Flower colour intensity depends on specialized cell shape
controlled by a Myb-related transcription factor 661
Ken-ichi Noda, Beverley
J. Glover, Paul Linstead & Cathie Martin
doi:10.1038/369661a0
First paragraph & References | PDF (613K)
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|
| | Sp1/egr-like zinc-finger protein required for endoderm
specification and germ-layer formation in Drosophila
664
Günter Brönner, Quynh Chu-LaGraff, Chris
Q. Doe, Barbara Cohen, Detlef Weigel, Heike Taubert & Herbert Jäckle
doi:10.1038/369664a0
First paragraph & References | PDF (732K)
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|
| | Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic
mice 669
Timothy C. Wang, Robert D. Cardiff, Lawrence Zukerberg, Emma Lees, Andrew Arnold & Emmett V. Schmidt
doi:10.1038/369669a0
First paragraph & References | PDF (589K)
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| | Solution structure of a pleckstrin-homology domain 672
Ho Sup Yoon, Philip J. Hajduk, Andrew M. Petros, Edward T. Olejniczak, Robert P. Meadows & Stephen W. Fesik
doi:10.1038/369672a0
First paragraph & References | PDF (445K)
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|
| | Structure of the pleckstrin homology domain from
-spectrin 675
Maria J. Macias, Andrea Musacchio, Hannes Ponstingl, Michael Nilges, Matti Saraste & Hartmut Oschkinat
doi:10.1038/369675a0
First paragraph & References | PDF (469K)
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|
| | A serine kinase regulates intracellular localization of splicing
factors in the cell cycle 678
Jian-Fang Gui, William
S. Lane & Xiang-Dong Fu
doi:10.1038/369678a0
First paragraph & References | PDF (766K)
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| | Guide to Authors | |
|
| | 683
doi:10.1038/369683a0
PDF (145K)
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| | Product Reviews | |
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| | Long PCR 684
As increasingly longer DNA targets are amplified reliably, new applications for PCR are becoming possible.
Suzanne Cheng, Sheng-Yung Chang, Patti Gravitt & Richard Respess
doi:10.1038/369684a0
References | PDF (268K)
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| | Tools of the research trade 686
New reagents to watch out for include 'live' cell
nucleic acid stains, a yeast transformation kit, a chemiluminescent
immunoblotting system and an expression system for the production of
soluble proteins in E. coli.
Diane Gershon
doi:10.1038/369686a0
PDF (467K)
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| | Employment Review | |
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| | The use of temporary laboratory scientists 689
A comparison of trends and costs between two European Union
countries, the United Kingdom and France, and the impact that
regulation can have on employment opportunities.
Ben Blackden
doi:10.1038/369689a0
PDF (232K)
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