| | Opinion |  |
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| | Health reform: reality strikes USA... 173
US President Bill Clinton's proposal for health-care reform is in for tough times now that it is being debated in Congress, because no one is entirely happy with the legislative details.
doi:10.1038/368173a0
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| | ... as UK faces the bill 173
The British government needs to redress its political neglect of health-related research.
doi:10.1038/368173b0
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| | British beef again 174
The possible German ban on British beef cannot be brushed aside, but needs European action.
doi:10.1038/368174a0
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| | News | |
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| | French geneticists split over terms of commercial use of DNA bank 175
Declan Butler
doi:10.1038/368175a0
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| | Maps show gains of reduced S02 emissions 175
Gabrielle Walker
doi:10.1038/368175b0
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| | UK 'must pay up' for costs of hospital merger 176
David Dickson
doi:10.1038/368176a0
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| | Hot-line will answer scientific queries 176
David Dickson
doi:10.1038/368176b0
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| | US universities oppose cap on federal funding 177
Colin Macilwain
doi:10.1038/368177a0
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| | Los Angeles plans for the worst 177
doi:10.1038/368177b0
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| | Germany uses BSE fears to seek ban on British beef 178
Alison Abbott
doi:10.1038/368178a0
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| | Biotechnology alliances set to double 178
Mike Ward
doi:10.1038/368178b0
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| | Delayed pay rises still leave concerns in Hungary 178
Alison Abbott
doi:10.1038/368178c0
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| | High-energy physics faces fight for survival 179
Colin Macilwain
doi:10.1038/368179a0
PDF (165K)
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| | Academic aid sets out for Yugoslavia 179
Declan Butler
doi:10.1038/368179b0
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| | High-energy physics faces fight for survival 179
doi:
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| | Health reforms 'could hit biotech companies' 180
Diane Gershon
doi:10.1038/368180a0
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| | French fossil-hunters defend the value of public support 180
Declan Butler
doi:10.1038/368180b0
PDF (146K)
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| | Japan seeks to reverse drop in interest in science 181
David Swinbanks
doi:10.1038/368181a0
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| | Soros pledges more money to back Russian science 181
Cari Levitin
doi:10.1038/368181b0
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| | Marie Curie 'should rest in Panthéon' 181
Declan Butler
doi:10.1038/368181c0
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| | Correspondence | |
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| | Employment in a rainforest 182
Anne McLaren
doi:10.1038/368182a0
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| | Education in India 182
A. N. Malviya
doi:10.1038/368182b0
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| | Jobs for the girls? 182
Shashi Kant & L. R. Murmu
doi:10.1038/368182c0
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| | Commentary |  |
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| | HIV in Zambia: myth or monster? 183
Despite attempts by a few journalists to portray the spread of AIDS in African countries as fictitious, the situation in Zambia shows that such views are completely misguided.
P. Godfrey-Faussett, R. Baggaley, G. Scott & M. Sichone
doi:10.1038/368183a0
References | PDF (304K)
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| | News and Views |  |
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| | Defending science against anti-science 185
There is a need for concerted action against the forces of anti-science; simply ignoring the critics will not suffice to counter the phenomenon.
John Maddox
doi:10.1038/368185a0
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| | Beauty and the beholder 186
Nancy L. Etcoff
doi:10.1038/368186a0
References | PDF (300K)
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| | Galton and composite portraits. 186
doi:10.1038/368186b0
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| | Safer solutions for chemists 187
K. P. Johnston
doi:10.1038/368187a0
References | PDF (278K)
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| | Unanimity waits in the wings 188
Patrick H. O'Farrell
doi:10.1038/368188a0
References | PDF (310K)
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| | Getting off to a rocky start 190
Steven V. W. Beckwith
doi:10.1038/368190a0
References | PDF (357K)
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| | Flummoxed by fake fruits 191
Peter D. Moore
doi:10.1038/368191a0
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| | Cosmic-ray hotspots 192
A. G. W. Cameron
doi:10.1038/368192a0
References | PDF (145K)
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| | Tracking neurotrophin function 193
Alun M. Davies
doi:10.1038/368193a0
References | PDF (356K)
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| | Fair copy 194
David Jones
doi:10.1038/368194a0
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| | Scientific Correspondence | |
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| | Origin of insect pollination 195
Makoto Kato & Tamiji Inoue
doi:10.1038/368195a0
References | PDF (164K)
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| | Growth rings in Mesozoic birds 196
Anusuya Chinsamy, Luis M. Chiappe & Peter Dodson
doi:10.1038/368196a0
References | PDF (431K)
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| | Cerebral asymmetry and handedness 197
Leonard E. White, Greg Lucas, Ann Richards & Dale Purves
doi:10.1038/368197a0
References | PDF (285K)
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| | Angiogenic activity of enzymes 198
Misako Haraguchi, Kazutaka Miyadera, Katsuo Uemura, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Kazutaka Yamada, Shin-ichi Akiyama & Yuji Yamada
doi:10.1038/368198a0
References | PDF (145K)
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| | Book Reviews | |
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| | Buy now, pay later 199
Tom Kirkwood reviews Human Longevity
By
David W.E. Smith.
doi:10.1038/368199a0
PDF (255K)
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| | Corpuscular science 200
David Knight reviews Robert Boyle Reconsidered
by
Michael Hunter and "Divulging of Useful Truths in Physick": The Medical Agenda of Robert Boyle
By
Barbara Beigun Kaplan.
doi:10.1038/368200a0
PDF (132K)
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| | Stellar beginnings 201
André Maeder reviews The Physics of Stars
By
A. C Philips.
doi:10.1038/368201a0
PDF (164K)
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| | Big bodies, big brains 201
doi:10.1038/368201b0
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| | Old boy 201
Bernard Wood reviews The Nariokotome Homo Erectus Skeleton
By
Alan Walker & Richard Leakey
doi:10.1038/368201c0
PDF (295K)
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| | Creatures deep and small 202
John D. Gage reviews Meiobenthology: The Microscopic Fauna in Aquatic Sediments
By
Olav Giere.
doi:10.1038/368202a0
PDF (148K)
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| | Articles |  |
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| | Ground-based imaging of extrasolar planets using adaptive optics 203
J. R. P. Angel
doi:10.1038/368203a0
Abstract & References | PDF (574K)
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| | Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein 208
Konrad Basler & Gary Struhl
doi:10.1038/368208a0
Abstract & References | PDF (1,024K)
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| | Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide 215
Lawrence J. Stern, Jerry H. Brown, Theodore S. Jardetzky, Joan C. Gorga, Robert G. Urban, Jack L. Strominger & Don C. Wiley
doi:10.1038/368215a0
Abstract & References | PDF (1,178K)
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| | Letters | |
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| | Production of 26A1 and other extinct radionuclides by low-energy heavy cosmic rays in molecular clouds 222
Donald D. Clayton
doi:10.1038/368222a0
First paragraph & References | PDF (376K)
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| | The curvature elastic-energy function of the lipid–water cubic mesophase 224
Hesson Chung & Martin Caffrey
doi:10.1038/368224a0
First paragraph & References | PDF (334K)
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| | Direct imaging of reptation for semiflexible actin filaments 226
J. Käs, H. Strey & E. Sackmann
doi:10.1038/368226a0
First paragraph & References | PDF (467K)
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| | Purification of C60 and C70 by selective complexation with calixarenes 229
Jerry L Atwood, George A. Koutsantonis & Colin L. Raston
doi:10.1038/368229a0
First paragraph & References | PDF (317K)
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| | Homogeneous catalytic hydrogenation of supercritical carbon dioxide 231
Philip G. Jessop, Takao Ikariya & Ryoji Noyori
doi:10.1038/368231a0
First paragraph & References | PDF (346K)
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| | Platform subsidence behind an active subduction zone 233
T. A Stern & W. E Holt
doi:10.1038/368233a0
First paragraph & References | PDF (375K)
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| | The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth 237
Theodore Fotsis, Youming Zhang, Michael S. Pepper, Herman Adlercreutz, Roberto Montesano, Peter Paul Nawroth & Lothar Schweigerer
doi:10.1038/368237a0
First paragraph & References | PDF (460K)
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| | Facial shape and judgements of female attractiveness 239
D. I. Perrett, K. A May & S. Yoshikawa
doi:10.1038/368239a0
First paragraph & References | PDF (500K)
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| | Simultaneous LTP of non-NMDA- and LTD of NMDA-receptor-mediated responses in the nucleus accumbens 242
Samuel B. Kombian & Robert C. Malenka
doi:10.1038/368242a0
First paragraph & References | PDF (458K)
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| | Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene 246
Richard J. Smeyne, Rüdiger Klein, Andreas Schnapp, Linda K. Long, Sherri Bryant, Anne Lewin, Sergio A. Lira & Mariano Barbacid
doi:10.1038/368246a0
First paragraph & References | PDF (615K)
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| | Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements 249
Rüdiger Klein, Inmaculada Silos-Santiago, Richard J. Smeyne, Sergio A. Lira, Riccardo Brambilla, Sherri Bryant, Li Zhang, William D. Snider & Mariano Barbacid
doi:10.1038/368249a0
First paragraph & References | PDF (465K)
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| | Co-evolution of ligand-receptor pairs 251
William R. Moyle, Robert K. Campbell, Rebecca V. Myers, Michael P. Bernard, Yi Han & Xiaoying Wang
doi:10.1038/368251a0
First paragraph & References | PDF (572K)
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| | Recombinant G-protein   -subunits activate the muscarinic-gated atrial potassium channel 255
Kevin D. Wickman, Jorge A. Iñiguez-Lluhi, Philip A. Davenport, Ronald Taussig, Grigory B. Krapivinsky, Maurine E. Linder, Alfred G. Gilman & David E. Clapham
doi:10.1038/368255a0
First paragraph & References | PDF (317K)
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| | Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer 258
C. Eric Bronner, Sean M. Baker, Paul T. Morrison, Gwynedd Warren, Leslie G. Smith, Mary Kay Lescoe, Michael Kane, Christine Earabino, James Lipford, Annika Lindblom, Pia Tannergård, Roni J. Bollag, Alan R. Godwin, David C. Ward, Magnus Nordenskj⊘ld, Richard Fishel, Richard Kolodner & R. Michael Liskay
doi:10.1038/368258a0
First paragraph & References | PDF (563K)
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| | Destabilization of the complete protein secondary structure on binding to the chaperone GroEL 261
Ralph Zahn, Claus Spitzfaden, Marcel Ottiger, Kurt Wüthrich & Andreas Plückthun
doi:10.1038/368261a0
First paragraph & References | PDF (576K)
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| | A large-conductance mechanosensitive channel in E. coli encoded by mscL alone 265
Sergei I. Sukharev, Paul Blount, Boris Martinac, Frederick R. Blattner & Ching Kung
doi:10.1038/368265a0
First paragraph & References | PDF (478K)
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| | Product Reviews | |
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| | Multi-target PCR analysis by capillary electrophoresis and laser-induced fluorescence 269
Quantitative analysis of polymerase chain reaction (PCR) amplified HIV-1 DNA or cDNA fragments is attained using an automated system that combines capillary-gel electrophoresis (CGE) for high-efficiency separation and laser-induced fluorescence (LIF) for high-sensitivity detection. This system enables the detection of PCR-amplified multiple target DNA or cDNA in the same tube by a single injection with high precision.
Wei Lu, Dai-Shu Han, Ju Yuan & Jean-Marie Andrieu
doi:10.1038/368269a0
References | PDF (386K)
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| | Tools of the trade 271
For the immunologist — an in vitro system for studying leukocyte transendothelial migration, assays for free radical markers, antibodies to nitric oxide synthases and an assortment of microplates.
Diane Gershon
doi:10.1038/368271a0
PDF (697K)
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