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Nature , 531-533 (8 October 1992) | doi:10.1038/359531a0;

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Evolution of sex determination and the Y chromosome: SRY-related sequences in marsupials

IN mammals, testis determination is under the control of the testis-determining factor borne by the Y chromosome1,2. SRY, a gene cloned from the sex-determining region of the human Y chromosome, has been equated with the testis-determining factor in man3–5 and mouse6,7.

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