Nature Publishing Group, publisher of Nature, and other science journals and reference works
Nature
my account e-alerts subscribe register
   
Tuesday 27 June 2017
Journal Home
Current Issue
AOP
Archive
Download PDF
References
Export citation
Export references
Send to a friend
More articles like this

Article
Nature 359, 380 - 387 (01 October 1992); doi:10.1038/359380a0

Continuum of overlapping clones spanning the entire human chromosome 21q

Ilya Chumakov*, Philippe Rigault, Sophie Guillou, Pierre Ougen*, Alain Billaut*, Ghislaine Guasconi, Patricia Gervy, Isabelle LeGall*, Pascal Soularue*, Laurent Grinas, Lydie Bougueleret*, Christine Bellanné-Chantelot*, Bruno Lacroix*, Emmanuel Barillot, Philippe Gesnouin, Stuart Pook, Guy Vaysseix*, Gerard Frelat, Annette Schmitz, Jean-Luc Sambucy*, Assumpcio Bosch§, Xavier Estivill§, Jean Weissenbach, Alain Vignal, Harold Riethman, David Cox£, David Patterson**, Kathleen Gardiner**, Masahira Hattori, Yoshiyuki Sakaki, Hitoshi Ichikawa, Misao Ohki, Denis Le Paslier*, Roland Heilig§§, Stylianos Antonarakis & Daniel Cohen*¶¶

* Centre d'Etude du Polymorphisme Humain (CEPH), 27 rue Juliette Dodu, 75010 Paris, France
Genethon, 1 rue de I'lnternationale, BP 59, 91002 Evry Cedex, France
Centre d'Energie Atomique, 68 Avenue Division LeClerc, 92260 Fontenay aux Roses, France
§Institut de Recerca Oncologica, Hospital Duran i Reynals Ctra Castelldefels, KM 2.7, Barcelona 08907, Spain
CNRS URA 1445, Institut Pasteur, 28 rue Docteur Roux, 75724 Paris, France
The Wistar Institute, 36th Street and Spruce, Philadelphia, Pennsylvania 19104, USA
£Neurogenetics Laboratory, University of California, 401 Parnassus Avenue, San Francisco, California 94143, USA
**Eleanor Roosevelt Institute, 1899 Gaylord Street, Denver, Colorado 80206, USA
The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai Minatoku, Tokyo 108, Japan
Saitama Cancer Center Research Institute, Ina-machi, Kitaadachi-gun, Saitama-ken 362, Japan
§§INSERM U184, Laboratoire de Génétique Moléculaire de Eucaryotes, 11 rue Humann, Strasbourg, France
Center for Medical Genetics, The Johns Hopkins University School of Medicine, 600 North Wolfe Street CMSC 1003, Baltimore, Maryland 21205, USA
¶¶To whom correspondence should be addressed.

A continuous array of overlapping clones covering the entire human chromosome 21q was constructed from human yeast artificial chromosome libraries using sequence-tagged sites as landmarks specifically detected by polymerase chain reaction. The yeast artificial chromosome contiguous unit starts with pericentromeric and ends with subtelomeric loci of 21q. The resulting order of sequence-tagged sites is consistent with other physical and genetic mapping data. This set of overlapping clones will promote our knowledge of the structure of this chromosome and the function of its genes.

------------------

References

1. Montanaro, V. et al. Am. J. hum. Genet. 48, 183−194 (1991). | PubMed | ChemPort |
2. Korenberg, J. R. & Tykowski, M. C. Cell 53, 391−400 (1988). | Article | PubMed | ChemPort |
3. Cox, D. R. et al. Science 250, 245−250 (1990). | PubMed | ISI | ChemPort |
4. Gardiner, K. et al. Somat. Cell molec. Genet. 14, 623−638 (1988). | PubMed | ChemPort |
5. Coulson, A., Sulston, J., Brenner, S. & Kam, J. Proc. natn. Acad. Sci. U.S.A. 83, 7821−7825 (1986). | ChemPort |
6. Olson, M. et al. Proc. natn. Acad. Sci. U.S.A. 83, 7826−7830 (1986). | ChemPort |
7. Evans, G. A. & Lewis, K. A. Proc. natn. Acad. Sci. U.S.A. 86, 5030−5034 (1989). | ChemPort |
8. Craig, G. et al. Nucleic Acids Res. 18, 2653−2660 (1990). | PubMed | ISI | ChemPort |
9. Stallings, R. L. et al. Proc. natn. Acad. Sci. U.S.A. 87, 6218−6222 (1990). | ChemPort |
10. Schlessinger, D. et al. Genomics 11, 783−793 (1991). | Article | PubMed | ISI | ChemPort |
11. Botstein, D. et al. Am. J. hum. Genet. 32, 314−331 (1980). | PubMed | ISI | ChemPort |
12. Cox, D. R. et al. Cytogenet. Cell Genet. 58, 800−826 (1991). | ISI |
13. Green, E. D. & Green, P. PCR Meth. Appl. 1, 77−90 (1991). | ChemPort |
14. Burke, D. T., Carle, G. F. & Olson, M. V. Science 236, 806−812 (1987). | PubMed | ISI | ChemPort |
15. Anand, R., Villasente, A. & Tyler-Smith, C. Nucleic Acids Res. 17, 4325−4333 (1989).
16. Larin, Z., Monaco, A. P. & Lehrach, H. Proc. natn. Acad. Sci. U.S.A. 88, 4123−4127 (1991). | ChemPort |
17. Albertsen, H. M. et al. Proc. natn. Acad. Sci. U.S.A. 87, 4256−4260 (1990). | ChemPort |
18. Chumakov, I. M. et al. Nature Genet. 1, 222−225 (1992). | Article | PubMed | ISI | ChemPort |
19. Olson, M. V. et al. Science 245, 1434−1435 (1989). | PubMed | ISI | ChemPort |
20. Ichikawa, H. et al. Proc. natn. Acad. Sci. U.S.A. 89, 23−27 (1992). | ChemPort |
21. Tanzi, R. E. et al. Genomics (in the press).
22. Van Keuren, M. et al. Am. J. med. Genet. 38, 793−804 (1989).
23. Gardiner, K. et al. EMBO J. 9, 25−34 (1990). | PubMed | ISI | ChemPort |
24. Riethman, H. et al. Proc. natn. Acad. Sci. U.S.A. 86, 991−995 (1989).
25. Rigault, P. Int. J. Genome Res. (in the press).
26. Warburton, P. E. et al. Genomics 11, 324−333 (1991). | Article | PubMed | ISI | ChemPort |
27. Assum, G. et al. Genomics 11, 397−404 (1991). | PubMed | ChemPort |
28. Petersen, M. B. et al. Genomics 9, 407−419 (1991). | Article | PubMed | ISI | ChemPort |



© 1992 Nature Publishing Group
Privacy Policy