| | Opinion |  |
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| | Is it "Oui or Nous ne savons pas"? 257
The uncertainty caused by the French referendum on Europe last Sunday could threaten many institutions of European collaboration. Responsibility for avoiding that outcome rests with the British.
doi:10.1038/359257a0
PDF (122K)
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| | Saving on health 257
Two prosperous countries in the West — Germany and the United States — are in trouble over health costs.
doi:10.1038/359257b0
PDF (241K)
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| | Rebuild research now 258
The temptation to cut back on research in the current financial crisis should be resisted.
doi:10.1038/359258a0
PDF (136K)
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| | News | |
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| | French court upholds use of animals, fines activists for theft of baboons 259
Declan Butler
doi:10.1038/359259a0
PDF (151K)
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| | Blow struck against US pork-barrel 259
Jeffrey Mervis
doi:10.1038/359259b0
PDF (151K)
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| | Confusion about form and function clouds launch of EC's Decade of the Brain 260
Alison Abbott
doi:10.1038/359260a0
PDF (351K)
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| | Crossing the border, crossing the ocean 260
Alun Anderson
doi:10.1038/359260b0
PDF (351K)
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| | First meeting of commission gives Massey a boost in plotting viable future for NSF 261
Jeffrey Mervis
doi:10.1038/359261a0
PDF (151K)
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| | User fees advance in Congress 261
Diane Gershon
doi:10.1038/359261b0
PDF (151K)
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| | New rules in Britain make it harder for older scientists to use animals 262
lan Mundell
doi:10.1038/359262a0
PDF (143K)
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| | Worthy proposals get second life 262
lan Mundell
doi:10.1038/359262b0
PDF (143K)
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| | US rejects French request to reopen AIDS patent deal 262
Christopher Anderson & Declan Butler
doi:10.1038/359262c0
PDF (143K)
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| | NIH cDNA patent rejected; backers want to amend law 263
Christopher Anderson
doi:10.1038/359263a0
PDF (152K)
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| | Emphasis on research blamed for problems at US universities 263
Traci Watson
doi:10.1038/359263b0
PDF (152K)
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| | Alberts emphasizes education as nominee to head NAS 264
Jeffrey Mervis
doi:10.1038/359264a0
PDF (157K)
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| | OST rows with tide in report on intellectual property 264
lan Mundell
doi:10.1038/359264b0
PDF (157K)
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| | Correspondence | |
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| | Rewriting the history of science 265
Alex Milne
doi:10.1038/359265a0
References | PDF (162K)
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| | Rewriting the history of science 265
Ralph Estling
doi:10.1038/359265b0
PDF (162K)
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| | Brown's observations confirmed 265
Brian J. Ford
doi:10.1038/359265c0
References | PDF (162K)
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| | Remedies for brain disorders 266
Giorglo Blgnami
doi:10.1038/359266a0
References | PDF (147K)
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| | Genetic influence 266
David Wasserman
doi:10.1038/359266b0
PDF (147K)
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| | Adders multiply 266
David C. Jolly
doi:10.1038/359266c0
PDF (147K)
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| | News and Views |  |
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| | The search for dark matter (contd) 267
An article with an arresting title puts forward a novel way of resolving the question whether the matter that holds the Universe together is 'cold' or 'hot' by showing that one kind of particle might fill both roles.
John Maddox
doi:10.1038/359267a0
PDF (149K)
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| | In search of the soluble 268
John Hardy & Mike Mullan
doi:10.1038/359268a0
References | PDF (251K)
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| | Fresh start for photonics 269
Larry R. Dalton
doi:10.1038/359269a0
References | PDF (250K)
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| | For our eyes only 270
Ed Harlow
doi:10.1038/359270a0
References | PDF (268K)
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| | Breaking out in spots 271
Harold Zirin
doi:10.1038/359271a0
PDF (144K)
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| | Barbara McClintock(1902−1992) 272
Gerald R. Fink
doi:10.1038/359272a0
PDF (187K)
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| | Rac and Rho in tune 273
Julian Downward
doi:10.1038/359273a0
References | PDF (268K)
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| | Merely the tip of the ice core 274
David Peel
doi:10.1038/359274a0
References | PDF (264K)
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| | Volcanic aerosols implicated 275
Guy Brasseur
doi:10.1038/359275a0
References | PDF (297K)
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| | Beyond the fringe 275
doi:10.1038/359275b0
PDF (145K)
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| | Eating in 275
doi:10.1038/359275c0
PDF (145K)
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| | Cosmic undoing 275
doi:10.1038/359275d0
PDF (145K)
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| | Sound moves 276
David Jones
doi:10.1038/359276a0
PDF (133K)
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| | Scientific Correspondence | |
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| | Rabies in wild dogs 277
Roger Burrows
doi:10.1038/359277a0
References | PDF (132K)
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| | Origin of rodents and guinea-pigs 277
Wen-Hslung Li, Winston A. Hide & Dan Graur
doi:10.1038/359277b0
References | PDF (251K)
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| | No Palaeocene 'mammal-like reptile' 278
Hans-Dieter Sues
doi:10.1038/359278a0
References | PDF (137K)
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| | Book Reviews |  |
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| | A trot through time 279
Patrick Cunningham reviews Horse Power: A History of the Horse and the Donkey in Human Societies
By
Juliet Glutton-Brock
doi:10.1038/359279a0
PDF (114K)
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| | Animist debate 280
Mark Ridley reviews The New Anthropomorphism
By
J. S. Kennedy
doi:10.1038/359280a0
PDF (179K)
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| | Animist debate 280
doi:10.1038/359280b0
PDF (179K)
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| | Critical days 281
David Shoenberg reviews Superconductivity: Its Historical Roots and Development from Mercury to the Ceramic Oxides
By
Per Fridtjof Dahl
doi:10.1038/359281a0
PDF (275K)
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| | Zeroing in on the cold 282
A. J. Leggett reviews Low Temperature Physics: An Introduction for Scientists and Engineers
By
P. V. E. McClintock, D. Meredith & J. K. Wigmore
doi:10.1038/359282a0
PDF (167K)
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| | Articles |  |
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| | Observation and possible causes of new ozone depletion in Antarctica in 1991 283
D. J. Hofmann, S. J. Oltmans, J. M. Harris, S. Solomon, T. Deshler & B. J. Johnson
doi:10.1038/359283a0
Abstract & References | PDF (775K)
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| | Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis 288
Eva Y.-H. P. Lee, Chi-Yao Chang, Nanpin Hu, Yi-Chun J. Wang, Chen-Ching Lai, Karl Herrup, Wen-Hwa Lee & Allan Bradley
doi:10.1038/359288a0
Abstract & References | PDF (1,257K)
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| | Effects of an Rb mutation in the mouse 295
Tyler Jacks, Amin Fazeli, Earlene M. Schmitt, Roderick T. Bronson, Margaret A. Goodell & Robert A. Weinberg
doi:10.1038/359295a0
Abstract & References | PDF (1,050K)
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| | Letters | |
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| | X-ray detection of the eclipsing millisecond pulsar PSR1957 +20 300
S. R. Kulkarni, E. S. Phinney, C. R. Evans & G. Hasinger
doi:10.1038/359300a0
First paragraph & References | PDF (537K)
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| | X-rays from the eclipsing pulsar 1957 +20 303
A. S. Fruchter, J. Bookbinder, M. R. Garcia & C. D. Bailyn
doi:10.1038/359303a0
First paragraph & References | PDF (231K)
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| | Star formation and the origin of stellar masses 305
Philipp Podsiadlowski & Nigel M. Price
doi:10.1038/359305a0
First paragraph & References | PDF (501K)
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| | Resolution of magnetic flux tubes on the Sun 307
C. U. Keller
doi:10.1038/359307a0
First paragraph & References | PDF (274K)
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| | Excited-state enhancement of optical nonlinearities in linear conjugated molecules 309
D. C. Rodenberger, J. R. Heflin & A. F. Garrto
doi:10.1038/359309a0
First paragraph & References | PDF (442K)
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| | Irregular glacial interstadials recorded in a new Greenland ice core 311
S. J. Johnsen, H. B. Clausen, W. Dansgaard, K. Fuhrer, N. Gundestrup, C. U. Hammer, P. Iversen, J. Jouzel, B. Stauffer & J. P. steffensen
doi:10.1038/359311a0
First paragraph & References | PDF (438K)
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| | Reconciling particulate organic carbon flux and sediment community oxygen consumption in the deep North Pacific 313
K. L. Smith Jr, R. J. Baldwin & P. M. Williams
doi:10.1038/359313a0
First paragraph & References | PDF (566K)
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| | Lack of nitrogen cycling in the Atacama Desert 316
James R. Ehleringer, Harold A. Mooney, Philip W. Rundel, R. David Evans, Beatrice Palma & Jose Delatorre
doi:10.1038/359316a0
First paragraph & References | PDF (470K)
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| | Predictable eye-head coordination during driving 318
Michael F. Land
doi:10.1038/359318a0
First paragraph & References | PDF (442K)
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| | Deficiency of the 50K dystrophin-associated glycoprotein in severe childhood autosomal recessive muscular dystrophy 320
Kiichiro Matsumura, Fernando M. S. Tomé, Huguette Collin, Kemal Azibi, Malika Chaouch, Jean-Claude Kaplan, Michel Fardeau & Kevin P. Campbell
doi:10.1038/359320a0
First paragraph & References | PDF (493K)
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| | Amyloid  -peptide is produced by cultured cells during normal metabolism 322
Christian Haass, Michael G. Schlossmacher, Albert Y. Hung, Carmen Vigo-Pelfrey, Angela Mellon, Beth L. Ostaszewski, Ivan Lieberburg, Edward H. Koo, Dale Schenk, David B. Teplow & Dennis J. Selkoe
doi:10.1038/359322a0
First paragraph & References | PDF (603K)
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| | Isolation and quantification of soluble Alzheimer's -peptide from biological fluids 325
Peter Seubert, Carmen Vigo-Pelfrey, Fred Esch, Michael Lee, Harry Dovey, Dave Davis, Sukanto Sinha, Michael Schiossmacher, Justine Whaley, Cathy Swindlehurst, Robert McCormack, Robert Wolfert, Dennis Selkoe, Ivan Lieberburg & Dale Schenk
doi:10.1038/359325a0
First paragraph & References | PDF (485K)
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| | Requirement for a functional Rb-1 gene in murine development 328
Alan R. Clarke, Els Robanus Maandag, Marian van Roon, Nathalie M. T. van der Lugt, Martin van der Valk, Martin L. Hooper, Anton Berns & Hein te Rielef
doi:10.1038/359328a0
First paragraph & References | PDF (533K)
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| | Inefficient positive selection of T cells directed by haematopoietic cells 330
Mark Bix & David Raulet
doi:10.1038/359330a0
First paragraph & References | PDF (649K)
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| | Elongation factor-1 gene determines susceptibility to transformation 333
Masaaki Tatsuka, Hiromi Mitsui, Morimasa Wada, Akihisa Nagata, Hiroshi Nojima & Hiroto Okayama
doi:10.1038/359333a0
First paragraph & References | PDF (638K)
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| | Cell transformation and activation of pp60
c-src
by overexpression of a protein tyrosine phosphatase 336
Xin Min Zheng, Yue Wang & Catherine J. Fallen
doi:10.1038/359336a0
First paragraph & References | PDF (711K)
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| | The candidate oncoprotein Bcl-3 is an antagonist of pSO/NF- B-mediated inhibition 339
Guido Franzoso, Vincent Bours, Sun Park, Michiyo Tomfta-Yamaguchi, Kathleen Kelly & Ulrich Siebenlist
doi:10.1038/359339a0
First paragraph & References | PDF (692K)
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| | Product Review | |
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| | The computing edge 343
Featured this week — a pocket-sized PC, workstations and a host of software programs for protein research, and graphics and data analysis.
doi:10.1038/359343a0
PDF (535K)
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| | Guide to Authors | |
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| | Guide to Authors 346
doi:10.1038/359346a0
PDF (144K)
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