| | Opinion |  |
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| | What to do with the former Soviet Union 377
doi:10.1038/355377a0
PDF (251K)
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| | An obdurate recession 378
doi:10.1038/355378a0
PDF (143K)
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| | An obdurate recession 378
doi:10.1038/355378b0
PDF (143K)
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| | News |  |
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| | Roche cuts controversial PCR fees, testing limits 379
Christopher Anderson
doi:10.1038/355379a0
PDF (149K)
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| | Frontiers win 379
David Swinbanks
doi:10.1038/355379b0
PDF (149K)
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| | Shakeup for Royal Observatories 380
Peter Aldhous
doi:10.1038/355380a0
PDF (182K)
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| | Leukaemia linked to radiation 381
Peter Aldhous
doi:10.1038/355381a0
PDF (156K)
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| | Orphan drug windfalls? 381
Diane Gershon
doi:10.1038/355381b0
PDF (156K)
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| | A gene library that goes "moo" 382
Christopher Anderson
doi:10.1038/355382a0
PDF (158K)
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| | Progress on animal patents 382
Peter Aldhous
doi:10.1038/355382b0
PDF (158K)
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| | New broom sweeps cleaner 383
John Maddox
doi:10.1038/355383a0
PDF (161K)
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| | UK sets 'early warning system' 383
Peter Aldhous
doi:10.1038/355383b0
PDF (163K)
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| | Correspondence |  |
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| | Freedom does not bring money 384
ZDENK SESTAK
doi:10.1038/355384a0
PDF (145K)
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| | Freedom does not bring money 384
N. G. BOCHKAREV, A. D. CHERNIN, Yu. N. EFREMOV, N. N. SAMUS' & A. V. ZASOV
doi:10.1038/355384b0
PDF (145K)
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| | Left out 384
RICARDO FERREIRA
doi:10.1038/355384c0
PDF (145K)
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| | Commentaries |  |
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| | Science against the odds in Poland 385
doi:10.1038/355385a0
PDF (419K)
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| | 'Happy accident for technology transfer 385
doi:10.1038/355385b0
PDF (135K)
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| | Grants scheme struggles ahead 386
doi:10.1038/355386a0
PDF (155K)
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| | A lifeline from abroad 387
doi:10.1038/355387a0
PDF (163K)
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| | Monopoly threatens variety 388
doi:10.1038/355388a0
PDF (308K)
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| | Where now for the Academy? 388
doi:10.1038/355388b0
PDF (155K)
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| | Shoestring budget slows reform 389
doi:10.1038/355389a0
PDF (172K)
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| | Democracy a mixed blessing 390
doi:10.1038/355390a0
PDF (147K)
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| | Entrepreneurs look for customers 390
doi:10.1038/355390b0
PDF (147K)
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| | News and Views |  |
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| | Russian science faces economic crisis 391
The Russian part of the ex-Soviet scientific enterprise is facing its
economic crisis with fortitude. But these are only early days, and there is
worse to come.
John Maddox
doi:10.1038/355391a0
PDF (153K)
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| | Growing old before our eyes 392
Achim Weiss
doi:10.1038/355392a0
References | PDF (267K)
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| | Dialogue with the cell cycle 393
Brenda J. Andrews
doi:10.1038/355393a0
References | PDF (277K)
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| | Snakes and female sexuality 395
G. A. Parker
doi:10.1038/355395a0
References | PDF (299K)
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| | New paths for random walkers 396
Michael F. Shlesinger
doi:10.1038/355396a0
References | PDF (302K)
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| | A remote sense for fossils 397
Bernard Wood
doi:10.1038/355397a0
References | PDF (266K)
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| | B destructive 398
doi:10.1038/355398a0
PDF (152K)
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| | Singular work 398
doi:10.1038/355398b0
PDF (152K)
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| | In a twist 398
doi:10.1038/355398c0
PDF (152K)
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| | Is no SNUs good news? 399
Lawrence M. Krauss
doi:10.1038/355399a0
References | PDF (278K)
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| | Black hole is M87's bright spot 399
Robert Poole
doi:10.1038/355399b0
PDF (144K)
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| | Counting stars 400
DAVID JONES
doi:10.1038/355400a0
PDF (152K)
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| | Scientific Correspondence |  |
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| | Doping of C60 with iodine 401
T. R. OHNO, G. H. KROLL, J. H. WEAVER, L. P. F. CHIBANTE & R. E. SMALLEY
doi:10.1038/355401a0
References | PDF (147K)
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| | Kiwi's egg 401
ELAIN MORGAN
doi:10.1038/355401b0
PDF (147K)
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| | Mount Etna C02 may affect climate 401
KEN CALDEIRA & MICHAEL R.
RAMPINO
doi:10.1038/355401c0
References | PDF (274K)
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| | More questions on forest decline 402
R. SIMONAITIS, K. J. OLSZYNA & J. F. MEAGHER
doi:10.1038/355402a0
References | PDF (142K)
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| | Maintenance of MHC polymorphism 402
AUSTIN L. HUGHES & MASTOSHI NEI
doi:10.1038/355402b0
PDF (269K)
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| | News and Views |  |
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| | Maintenance of MHC polymorphism 403
ADRIAN V. S. HILL, DOMINIC KWIATKOWSKI, ANDREW J. McMICHAEL, BRIAN M. GREENWOOD & STEPHEN BENNET
doi:10.1038/355403a0
References | PDF (154K)
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| | Scientific Correspondence |  |
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| | Language gap 403
IAIN DAVIDSON & WILLIAM
NOBLE
doi:10.1038/355403b0
PDF (281K)
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| | Language gap 404
JEREMY J. D. GREENWOOD
doi:10.1038/355404a0
PDF (154K)
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| | Language gap 404
ROBERT FOLEY
doi:10.1038/355404b0
References | PDF (154K)
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| | Book Review |  |
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| | Imperious innovator 405
Leonard Krishtalka reviews An Agenda for Antiquity: Henry Fairfield Osborn and
Vertebrate Paleontology at the American Museum of Natural History,
1890-1935
By
Ronald Rainger
doi:10.1038/355405a0
PDF (406K)
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| | News |  |
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| | Fly River trumpet-eared bat 406
doi:10.1038/355406a0
PDF (236K)
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| | Book Reviews |  |
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| | Duplicating success 406
Sue Wickner reviews DNA Replication, Second EditionArthur Tania KornbergBaker
doi:10.1038/355406b0
PDF (368K)
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| | Coffee-table cosmology 407
Joseph Silk reviews The Natural History of the Universe
By
Colin A. Ronan, Alan Lightman, Jay M.
Pasachoff & Isaac Asimov
doi:10.1038/355407a0
PDF (150K)
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| | Unknotting epistemology 408
John Ziman reviews The Philosophy of Science
By
Richard Philip J. D. BoydGasperTrout
doi:10.1038/355408a0
PDF (151K)
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| | Review Article |  |
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| | Molecular dissection of the secretory pathway 409
A combination of biochemistry in animal cell-free systems and
genetics in yeast is revealing the molecular machinery of the secretory pathway
of eukaryotes. Transporting vesicles have a simple coat structure and employ a
general mechanism for fusion that is conserved in evolution.
James E. Rothman & Lelio Orci
doi:10.1038/355409a0
References | PDF (874K)
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| | News |  |
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| | Evidence from Southern Ocean sediments for the effect of North Atlantic deep-water flux on climate 416
The Southern Ocean is perhaps the only region where fluctuations in the
global influence of North Atlantic Deep Water (NADW) can be monitored
unambiguously in single deep-sea cores. A carbon isotope record from benthic
foraminifera in a Southern Ocean core reveals large and rapid changes in the
flux of NADW during the last deglaciation, and an abrupt increase in the NADW
production rate which immediately preceded large-scale melting of the Northern
Hemisphere ice sheets. This sudden strengthening of the NADW thermoha-line cell
provides strong evidence for the importance of NADW in glacial-interglacial
climate change.
Christopher D. Charles & Richard G. Fairbanks
doi:10.1038/355416a0
References | PDF (577K)
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| | Letters |  |
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| | Identification of features due to H3
+ in the infrared spectrum of supernova 1987A 420
Steven Miller, Jonathan Tennyson, Stephen Lepp & Alexander Dalgarno
doi:10.1038/355420a0
First paragraph & References | PDF (317K)
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| | Observation of gradual brightening of P Cygni due to stellar
evolution 422
Mart J. H. de Groot & Henny J. G. L. M. Lamers
doi:10.1038/355422a0
First paragraph & References | PDF (231K)
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| | Territory covered by N diffusing particles 423
Hernan Larralde, Paul Trunfio, Shlomo Havlin, H. Eugene Stanley & George H. Weiss
doi:10.1038/355423a0
First paragraph & References | PDF (530K)
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| | Crumpled and collapsed conformation in graphite oxide membranes 426
Xin Wen, Carl W. Garland, Terence Hwa, Mehran Kardar, Etsuo Kokufuta, Yong Li, Michal Orkisz & Toyoichi Tanaka
doi:10.1038/355426a0
First paragraph & References | PDF (374K)
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| | Magic numbers and stable structures for fullerenes, fullerides and fullerenium ions 428
Patrick W. Fowler & David E. Manolopoulos
doi:10.1038/355428a0
First paragraph & References | PDF (361K)
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| | Multiple phases of polymer gels 430
Masahiko Annaka & Toyoichi
Tanaka
doi:10.1038/355430a0
First paragraph & References | PDF (312K)
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| | Observation of hypervalent CLi6 by Knudsen-effusion mass
spectrometry 432
Hiroshi Kudo
doi:10.1038/355432a0
First paragraph & References | PDF (332K)
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| | Increase in global atmospheric concentrations of mercury inferred from measurements over the Atlantic Ocean 434
F. Slemr & E. Langer
doi:10.1038/355434a0
First paragraph & References | PDF (446K)
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| | Large-scale mantle convection and the history of subduction 437
Mark A. Richards & David C. Engebretson
doi:10.1038/355437a0
First paragraph & References | PDF (561K)
|
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| | Why do female adders copulate so frequently? 440
Thomas Madsen, Richard Shine, Jon
Loman & Thomas Håkansson
doi:10.1038/355440a0
First paragraph & References | PDF (263K)
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| | Retinoid X receptor is an auxiliary protein for thyroid hormone and
retinoic acid receptors 441
Xiao-kun Zhang, Birgit Hoffmann, Paul B.-V. Tran, Gerhart Graupner & Magnus Pfahl
doi:10.1038/355441a0
First paragraph & References | PDF (878K)
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| | Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling 446
Steven A. Kliewer, Kazuhiko Umesono, David J. Mangelsdorf & Ronald M. Evans
doi:10.1038/355446a0
First paragraph & References | PDF (636K)
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| | Control of DNA synthesis genes in fission yeast by the cell-cycle gene
cdclO
+
449
Noel F. Lowndes, Christopher J. Mclnerny, Anthony L. Johnson, Peter A. Fantes & Leland H. Johnston
doi:10.1038/355449a0
First paragraph & References | PDF (638K)
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| | Expression of members of the putative olfactory receptor gene family in mammalian germ cells 453
Marc Parmentier, Frédéric Libert, Stéphane
Schurmans, Serge Schiffmann, Anne
Lefort, Dominique Eggerickx, Catherine
Ledent, Catherine Mollereau, Catherine Gérard, Jason
Perret, Anton Grootegoed & Gilbert
Vassart
doi:10.1038/355453a0
First paragraph & References | PDF (402K)
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| | Different conformations for the same polypeptide bound to chaperones DnaK and GroEL 455
Samuel J. Landry, Robert Jordan, Roger McMacken & Lila M. Gierasch
doi:10.1038/355455a0
First paragraph & References | PDF (361K)
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| | A transcriptional hierarchy involved in mammalian cell-type
specification 457
Calvin J. Kuo, Pamela B. Conley, Lei
Chen, Frances M. Sladek, James E. Darnell Jr & Gerald R. Crabtree
doi:10.1038/355457a0
First paragraph & References | PDF (618K)
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| | Characterization of cDNA for the large subunit of the transcription
initiation factor TFIIF 461
Teijiro Aso, Haren A. Vasavada, Tatsuo Kawaguchi, F. Joseph Germino, Subinay Ganguly, Shigetaka Kitajima, Sherman M. Weissman & Yukio
Yasukochi
doi:10.1038/355461a0
First paragraph & References | PDF (482K)
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| | A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II 464
Ann Finkelstein, Corwin F. Kostrub, Joyce Li, David P. Chavez, Bo Qing Wang, Shi Min Fang, Jack Greenblatt & Zachary F. Burton
doi:10.1038/355464a0
First paragraph & References | PDF (566K)
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| | Type III restriction enzymes need two inversely oriented recognition sites
for DNA cleavage 467
Andreas Meisel, Thomas A. Bickle, Detlev H. Kriiger & Cornelia Schroeder
doi:10.1038/355467a0
First paragraph & References | PDF (361K)
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| | Novel NADPH-binding domain revealed by the crystal structure of aldose
reductase 469
J.-M. Rondeau, F. Tête-Favier, A Podjarny, J.-M. Reymann, P. Barth, J.-F. Biellmann & D. Moras
doi:10.1038/355469a0
First paragraph & References | PDF (490K)
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| | Free R value: a novel statistical quantity for assessing the accuracy of crystal structures 472
Axel T. Brünger
doi:10.1038/355472a0
First paragraph & References | PDF (433K)
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| | Product Reviews |  |
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| | Antigenized antibodies 476
A new process, antigenization of antibodies, consisting of the expression of oligopeptides in the hypervariable loops of an antibody molecule is described. The potential applications of antigenized antibodies are discussed.
Maurizio Zanetti
doi:10.1038/355476a0
References | PDF (267K)
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| | Immunochemicals to order 478
A new chemiluminescent substrate for alkaline phosphatase, a custom monoclonal anti-peptide antibody service and a host of monoclonal antibodies - research tools for the immunologist.
doi:10.1038/355478a0
PDF (537K)
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