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Review
Nature 344, 503-508 (5 April 1990) | doi:10.1038/344503a0
Universal control mechanism regulating onset of M-phase
Paul Nurse
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Abstract
The onset of M-phase is regulated by a mechanism common to all eukaryotic cells. Entry into M-phase is determined by activation of the p34cdc2 protein kinase which requires p34cdc2 dephosphorylation and association with cyclin.
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