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Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis

Abstract

We have cloned the paired gene of Drosophila melanogaster, a pair-rule gene required for the establishment of proper segmentation. The transcriptional pattern in young embryos shows developmental polarities along the antero-posterior and dorso-ventral axes. Transcripts, initially expressed with a double-segment periodicity, switch to a single-segment repeat during syncytial blastoderm.

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Kilchherr, F., Baumgartner, S., Bopp, D. et al. Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis. Nature 321, 493–499 (1986). https://doi.org/10.1038/321493a0

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