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Nature 318, 323-329 (28 November 1985) | doi:10.1038/318323a0

Vaccination and herd immunity to infectious diseases

Roy M. Anderson & Robert M. May*

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An understanding of the relationship between the transmission dynamics of infectious agents and herd immunity provides a template for the design of effective control programmes based on mass immunization. Mathematical models of the spread and persistence of infection provide important insights into the problem of how best to protect the community against disease.