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Article
Nature 310, 203-207 (19 July 1984) | doi:10.1038/310203a0; Accepted 18 June 1984
From grasshopper to Drosophila: a common plan for neuronal development
John B. Thomas*, Michael J. Bastiani*, Michael Bate† & Corey S. Goodman*
- *Department of Biological Sciences, Stanford University, Stanford, California 94305, USA
- †Department of Zoology, Cambridge University, Downing Street, Cambridge CB2 3EJ, UK
Abstract
Little is known about the mechanisms that generate neuronal specificity during development. Whereas the grasshopper embryo has been an ideal system for a cellular analysis of neuronal development, the Drosophila embryo has obvious attributes for a molecular genetic analysis. Here we show that the early Drosophila embryo is a miniature replica of the grasshopper embryo in terms of its identified neurones, their growth cones and their selective fasciculation choices, thus opening the way for a combined cellular and molecular genetic analysis of cell recognition during neuronal development in Drosophila.
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